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Fernanda Faião Flores

CV Lattes ResearcherID


Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Dr. Fernanda Faião Flores worked as a postdoctoral fellow at Moffitt Cancer Center, Tampa, Florida, United States (2017-2019) and at School of Pharmaceutical Sciences - University of São Paulo, Brazil (2013-2017). She obtained her PhD in 2013 at School of Medicine - University of São Paulo, Brazil (2009-2013) on the investigation of the antiproliferative and cytotoxic effects of new compounds and therapies for cancer treatment. She held three months of her PhD at the University of Barcelona (Spain). Her career focus on the development and application of new therapies to cancer treatment and in vitro alternative methods to replace animal testing, human skin biology, mechanistic cell signaling and evaluation of pathways in distinct cell types. As a Postdoc in 2013-2017 at the University of Sao Paulo, at the Skin Biology group, the development of "in vivo like" human skin was her major interest with drug target therapies aiming melanoma treatment. In 2015-2016, she became a visiting Postdoc at the Moffitt Cancer Center in USA, and then in 2017-2019 as a Postdoctoral fellow of the same institution. Her main goal was to expand the research on melanoma therapy and the study of uveal melanoma, the most common and devastating form of eye cancer. She has also participated actively in the training of a number of junior lab members and a number of Moffitt, University of South Florida and University of Sao Paulo graduate students who have rotated through the labs. (Source: Lattes Curriculum)

Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated December 07, 2019
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications10
Citations122
Cit./Article12.2
Data from Web of Science

FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; PIRES CAMILLO, MARIA APARECIDA; MARIA-ENGLER, SILVYA STUCHI; GRASSI RICI, ROSE ELI; SOUZA SARKIS, JORGE EDUARDO; MARIA, DURVANEI AUGUSTO. Boron uptake in normal melanocytes and melanoma cells and boron biodistribution study in mice bearing B16F10 melanoma for boron neutron capture therapy. RADIATION AND ENVIRONMENTAL BIOPHYSICS, v. 51, n. 3, p. 319-329, . Web of Science Citations: 4.

SANDRI, SILVANA; FAIAO-FLORES, FERNANDA; TIAGO, MANOELA; PENNACCHI, PAULA COMUNE; MASSARO, RENATO RAMOS; ALVES-FERNANDES, DEBORA KRISTINA; BERARDINELLI, GUSTAVO NORIZ; EVANGELISTA, ADRIANE FEIJO; VAZQUEZ, VINICIUS DE LIMA; REIS, RUI MANUEL; et al. Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation. PHARMACOLOGICAL RESEARCH, v. 111, p. 523-533, . Web of Science Citations: 22.

FAIAO-FLORES, F.; ALVES-FERNANDES, D. K.; PENNACCHI, P. C.; SANDRI, S.; VICENTE, A. L. S. A.; SCAPULATEMPO-NETO, C.; VAZQUEZ, V. L.; REIS, R. M.; CHAUHAN, J.; GODING, C. R.; et al. Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells. Oncogene, v. 36, n. 13, p. 1849-1861, . Web of Science Citations: 22.

MASSARO, R. R.; FAIAO-FLORES, F.; REBECCA, V. W.; SANDRI, S.; ALVES-FERNANDES, D. K.; PENNACCHI, P. C.; SMALLEY, K. S. M.; MARIA-ENGLER, S. S.. Inhibition of proliferation and invasion in 2D and 3D models by 2-methoxyestradiol in human melanoma cells. PHARMACOLOGICAL RESEARCH, v. 119, p. 242-250, . Web of Science Citations: 6.

FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; MARIA-ENGLER, SILVYA STUCHI; SOTO-CERRATO, VANESSA; PEREZ-TOMAS, RICARDO; MARIA, DURVANEI AUGUSTO. The curcumin analog DM-1 induces apoptotic cell death in melanoma. TUMOR BIOLOGY, v. 34, n. 2, p. 1119-1129, . Web of Science Citations: 15.

FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; SOTO-CERRATO, VANESSA; ESPONA-FIEDLER, MARGARITA; PEREZ-TOMAS, RICARDO; MARIA, DURVANEI AUGUSTO. Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells. TUMOR BIOLOGY, v. 34, n. 2, p. 1235-1243, . Web of Science Citations: 10.

FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; PARDI, PAULO CELSO; MARIA, DURVANEI AUGUSTO. DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phe nolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment. TUMOR BIOLOGY, v. 33, n. 3, SI, p. 775-785, . Web of Science Citations: 13.

FAIÃO-FLORES‚ F.; SUAREZ‚ J.A.Q.; PARDI‚ P.C.; MARIA‚ D.A.. DM-1‚ sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1‚ 4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment. TUMOR BIOLOGY, p. 1-11, .

FAIAO-FLORES, FERNANDA; EMMONS, MICHAEL F.; DURANTE, MICHAEL A.; KINOSE, FUMI; SAHA, BISWARUP; FANG, BIN; KOOMEN, JOHN M.; CHELLAPPAN, SRIKUMAR P.; MARIA-ENGLER, SILVYA STUCHI; RIX, UWE; et al. HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical Cancer Research, v. 25, n. 18, p. 5686-5701, . Web of Science Citations: 2.

FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; FRUET, ANDREA COSTA; MARIA-ENGLER, SILVYA STUCHI; PARDI, PAULO CELSO; MARIA, DURVANEI AUGUSTO. Curcumin Analog DM-1 in Monotherapy or Combinatory Treatment with Dacarbazine as a Strategy to Inhibit In Vivo Melanoma Progression. PLoS One, v. 10, n. 3, . Web of Science Citations: 14.

FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; MARIA-ENGLER, SILVYA STUCHI; TIAGO, MANOELA; CAPELOZZI, VERA LUIZA; GIORGI, RICARDO RODRIGUES; MARIA, DURVANEI AUGUSTO. Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy. PLoS One, v. 8, n. 3, . Web of Science Citations: 14.

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