Flávia Luciana Beltrame
CV Lattes
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Universidade Paulista (UNIP). Vice-Reitoria de Pós-Graduação e Pesquisa (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Biomedicina from Universidade Estadual de Londrina (2005), master's at Morphology from Universidade Federal de São Paulo (2009) and doctorate at Morphology from Universidade Federal de São Paulo (2014). Has experience in Morphology, focusing on Histology, acting on the following subjects: ratos, testículos, álcool, estresse and imobilização. (Source: Lattes Curriculum)
- Effect of cimetidine on the epididymal histoarchitecture and evaluation of sperm DNA of rats treated with cimetidine and supplemented with B12, BP.PD
Abstract
Cimetidine is clinically used as antiulcer, competing for histamine H2 receptors in gastric parietal cells. Nowadays, this drug has also been used as an adjuvant in some types of cancer therapy because its antiangiogenic effect. This drug also seems to antagonize androgen receptors, exerting an antiandrogenic effect, which has been strongly related to changes in the male reproductive sy...
- Histopathological evaluation of interstitial tissue in cimetidine-treated rats and role of Vitamin B12 on the spermatogenic repair, BP.DR
| 1 / 0 | Ongoing research grants |
| 3 / 2 | Completed scholarships in Brazil |
| 4 / 2 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 6 |
| Citations | 48 |
| Cit./Article | 8.0 |
| Data from Web of Science | |
KOSHIMIZU, JULIANA Y.; BELTRAME, FLAVIA L.; DE PIZZOL, JR., JOSE P.; CERRI, PAULO S.; CANEGUIM, BRENO H.; SASSO-CERRI, ESTELA. NF-kB overexpression and decreased immunoexpression of AR in the muscular layer is related to structural damages and apoptosis in cimetidine-treated rat vas deferens. Reproductive Biology and Endocrinology, v. 11, APR 9 2013. Web of Science Citations: 14.
BELTRAME, FLAVIA L.; SASSO-CERRI, ESTELA. Vitamin B-12-induced spermatogenesis recovery in cimetidine-treated rats: effect on the spermatogonia number and sperm concentration. ASIAN JOURNAL OF ANDROLOGY, v. 19, n. 5, p. 567-572, SEP-OCT 2017. Web of Science Citations: 3.
BELTRAME, FLAVIA L.; YAMAUTI, CAROLINE T.; CANEGUIM, BRENO H.; CERRI, PAULO S.; MIRAGLIA, SANDRA M.; SASSO-CERRI, ESTELA. Cimetidine-induced vascular cell apoptosis impairs testicular microvasculature in adult rats. HISTOLOGY AND HISTOPATHOLOGY, v. 27, n. 10, p. 1343-1351, OCT 2012. Web of Science Citations: 12.
BELTRAME, FLAVIA L.; CANEGUIM, BRENO H.; MIRAGLIA, SANDRA M.; CERRI, PAULO S.; SASSO-CERRI, ESTELA. Vitamin B-12 Supplement Exerts a Beneficial Effect on the Seminiferous Epithelium of Cimetidine-Treated Rats. Cells Tissues Organs, v. 193, n. 3, p. 184-194, 2011. Web of Science Citations: 12.
BELTRAME, FLAVIA LUCIANA; DE SANTI, FABIANE; VENDRAMINI, VANESSA; LOURENCO CABRAL, REGINA ELIZABETH; MIRAGLIA, SANDRA MARIA; CERRI, PAULO SERGIO; SASSO-CERRI, ESTELA. Vitamin B-12 Prevents Cimetidine-Induced Androgenic Failure and Damage to Sperm Quality in Rats. FRONTIERS IN ENDOCRINOLOGY, v. 10, JUL 10 2019. Web of Science Citations: 0.
BELTRAME, FLAVIA L.; CERRI, PAULO S.; SASSO-CERRI, ESTELA. Cimetidine-induced Leydig cell apoptosis and reduced EG-VEGF (PK-1) immunoexpression in rats: Evidence for the testicular vasculature atrophy. REPRODUCTIVE TOXICOLOGY, v. 57, p. 50-58, NOV 2015. Web of Science Citations: 7.