CV Lattes
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Centro Universitário FIEO (2006), master's at Imunologia from Instituto de Ciências Biomédicas (2010) and doctorate at Programa de Pós-graduação em Imunologia from Instituto de Ciências Biomédicas IV (2014). Has experience in Immunology, focusing on Immunology, acting on the following subjects: imunossupressão, receptores de reconhecimento., purificação celular and proliferação celular. (Source: Lattes Curriculum)
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Secretory/excretory products from helminths exert a suppressive effect on the immune system, ensuring its survival in the host. High molecular weight components from Ascaris suum extract (PI) directly modulate the dendritic cells (DCs) maturation, inhibiting the expression of costimulatory and MHC-II molecules and consequent lymphocytes T proliferation. This PI effect on DCs is independen…
Helminths, and their products are potent immunomodulators. Work carried out with extract of Ascaris suum showed that the high molecular weight components (PI) contained in it suppress the immune response induced by ovalbumin (OVA). PI inhibits the expression of MHC-II molecules and costimulatory antigen presenting cells (APCs) such as dendritic cells (DCs) and thus its ability to induce p…
| 4 / 2 | Completed scholarships in Brazil |
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