Roberta Sessa Stilhano Yamaguchi
CV Lattes
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Fundação Arnaldo Vieira de Carvalho. Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Has experience in Genetics, focusing on Human and Medical Genetics, acting on the following subjects: phic31, mucopolissacaridosis I, terapia gênica, vetores não-virais and plasmídeo. (Source: Lattes Curriculum)
- Study of AT1a receptor silencing in autophagy and mitophagy in primary culture from skeletal muscle cells, BP.IC
Abstract
Cells have their own mechanisms to maintain the homeostasis. Autophagy is based on self-destruction and selective elimination of dysfunctional intracellular components, in which the cell relocates unneeded nutrients to more essential processes. Mitophagy is the sequestration of the mitochondria by the autophagosome followed by its degradation in the lysosomes. Both autophagy and mitopha...
- Muscle injury treatment by gene therapy associated with alginate hydrogel and autophagy induction, BP.PD
Abstract
Fibrosis is characterized by an excessive accumulation of extracellular matrix components and is one of the main sequelae acquired after muscle injury. It is most prevalent in severe injuries in which healing occurs slowly and prevents proper muscle contraction - which can lead to muscle contractures and chronic pain. Besides being an important aggravating factor of muscular dystrophies...
- Gene therapy for reduction of fibrosis in a model of SPONTENOUSLY hypertensive rats, BP.DR
Abstract
Fibrosis is a major acquired sequel after muscle injury. In more severe injuries, in which healing occurs slowly, fibrosis prevents the proper muscle contraction and can lead to chronic pain and muscle contractures. In addition to functional loss, scar tissue tends to suffer further injury due to the changing of nature of tissue. These events lead professional athletes to abandon their ...
(Only some records are available in English at this moment)
- Gene therapy for reduction of fibrosis in a model of spontenously hypertensive rats, BE.EP.DR
Abstract
Fibrosis is a major acquired sequel after muscle. The fibrotic process prevents proper muscle contraction and can lead to muscle contractures and chronic pain. In more severe injuries, in which healing occurs slowly, fibrosis prevents the proper muscle contraction and can lead to chronic pain and muscle contractures. In addition to functional loss, scar tissue tends to suffer further in...
| 5 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 6 / 5 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 3 |
| Citations | 17 |
| Cit./Article | 5.7 |
| Data from Web of Science | |
STILHANO, ROBERTA SESSA; SAMOTO, VIVIAN YOCHIKO; SILVA, LEONARDO MARTINS; PEREIRA, GUSTAVO JOSE; ERUSTES, ADOLFO GARCIA; SMAILI, SORAYA SOUBHI; HAN, SANG WON. Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor. PLoS One, v. 12, n. 10, OCT 23 2017. Web of Science Citations: 1. (15/20206-8, 12/00753-6)
MADRIGAL, JUSTIN L.; STILHANO, ROBERTA S.; SILTANEN, CHRISTIAN; TANAKA, KIMBERLY; REZVANI, SABAH N.; MORGAN, RYAN P.; REVZIN, ALEXANDER; HAN, SANG W.; SILVA, EDUARDO A.. Microfluidic generation of alginate microgels for the controlled delivery of lentivectors. JOURNAL OF MATERIALS CHEMISTRY B, v. 4, n. 43, p. 6989-6999, NOV 21 2016. Web of Science Citations: 10. (15/20206-8, 12/00753-6)
MATSUMOTO MARTIN, PRISCILA KEIKO; STILHANO, ROBERTA SESSA; SAMOTO, VIVIAN YOCHIKO; TAKIYA, CHRISTINA MAEDA; PERES, GIOVANI BRAVIN; CORREA DA SILVA MICHELACCI, YARA MARIA; DA SILVA, FLAVIA HELENA; PEREIRA, VANESSA GONCALVES; D'ALMEIDA, VANIA; NAVARRO MARQUES, FABIO LUIZ; et al. Mesenchymal Stem Cells Do Not Prevent Antibody Responses against Human alpha-L-Iduronidase when Used to Treat Mucopolysaccharidosis Type I. PLoS One, v. 9, n. 3, MAR 18 2014. Web of Science Citations: 6. (08/56529-1, 09/52235-6, 08/56530-0)