graduate at Medicina from Faculdade de Medicina da Universidade de São Paulo (1986) and ph.d. at Medicina from Faculdade de Medicina da Universidade de São Paulo (1998). Has experience in Medicine, acting on the following subjects: superoxide, nad p h oxidase, endothelium, vascular and injury. (Source: Lattes Curriculum)
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The emergency physician's ability to quickly diagnose and make a prognosis about the evolution of a seriously ill patient can not only save lives but also help to reduce the burden on medical services. Unfortunately, not all diseases have specific markers that can help physicians in this decision (as is the case of troponin in patients with acute myocardial infarction). So our main goal i…
Obesity affects more than 400 million subjects in the world and projections for the next 15 years predict an overall prevalence of up to 20%. In developing countries, such as Brazil a rapid nutritional transition provided by the recent economical growth has led to a unique condition on which the malnourished persist in parallel with an increasing number of obese subjects. It is expected t…
The current Covid-19 pandemic has affected more than 920,000 people and killed more than 46,000 worldwide. Most affected patients have a mild condition, but a small percentage, from the percentage point of view, but large in absolute numbers, may have a severe acute respiratory syndrome (SARS), with fever, cough, pulmonary infiltrates and hypoxemia, and may progress for respiratory failur…
There is evidence that obesity complications such as type 2 diabetes and dyslipidemia can be attributed, at least partially, to the inflammatory response that occurs within adipose tissue.However, it is still unclear whether inflammation alone may play a role in the genesis of obesity. We also do not know the influence of an acute inflammatory event, such as that observed in sepsis, on en…
The family of transcriptional coactivators PGC-1 comprises three members (PGC-1±, PGC-1² and PRC), with extensive homology, but with different functions and expression patterns. Their main function is related to mitochondrial biogenesis and function. Moreover, they play key roles in controlling energy homeostasis, including hepatic gluconeogenesis, lipoprotein metabolism, thermogenesis, c…
(Only some records are available in English at this moment)
There is a huge shortage of data on emergency care patient care throughout Brazil. This lack of data is even more evident when we focus attention on the elderly population.In this project, we aim to identify the population of patients seeking an Emergency Service, particularly those over 60, their clinical and laboratory differences from younger populations, and to assess whether severity…
Delirium is defined as a state of a lowered level of consciousness, with a sudden onset or rapid evolution, which may be associated with agitation and hallucinations. It occurs more commonly in the elderly, as a complication of other disorders, whether infectious, toxic, or metabolic. Its diagnosis is based on the clinical picture that may be difficult to be perceived initially. There is …
In recent years we have witnessed an exponential increase in data processing and storage capacity in digital form, as well as statistical analysis capable of making the analysis of this data useful information.From a generic point of view, the concept of Big Data refers to the daily generation of a huge and very diverse amount of data that can no longer be analyzed by humans alone. One of…
The increase in the adipose subcutaneous tissue is related to very prevalent diseases such as obesity and the lymphedema secondary to lymphatic obstruction (most commonly associated to cancer treatment). Recently, it was developed an experimental model in which the lymphatic vessels blockage in the proximal portion of mice tails leads to the development of subcutaneous deposits of fat, ve…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 7 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 7 / 5 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 18 / 13 | All research grants and scholarships |
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CV Lattes
ORCID