CV Lattes
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Pontifícia Universidade Católica de Campinas (PUC-CAMP). Centro de Ciências da Vida (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from Paulista State University Júlio de Mesquita Filho (1994), Master in Biological Sciences (Pharmacology) from Paulista State University Júlio de Mesquita Filho (1997) and PhD in Pharmacology from University of São Paulo (2001). Develop research in the field of Gastrointestinal Iinflammation, Obesity, Aging and Functional/Health Food. (Source: Lattes Curriculum)
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The elderly population with or without associated comorbidities, such as diabetes and cardiovascular disease is the most vulnerable group to COVID-19 mortality. Cell senescence is the process of cell aging that increases during the progression of chronic diseases (such as diabetes) and with aging, resulting in irreversible arrest of the cell cycle controlled by the p53 / p21 and p16 / Rb …
Structured lipids are triacylglycerols restructured in relation to their composition or distribution of fatty acids in the glycerol backbone in order to modify physicochemical or nutritional properties. Structured lipids containing behenic acid, a long chain saturated fatty acid, are partially absorbed and can act as inhibitors of pancreatic lipase in the intestine, reducing lipid absorpt…
Weight loss dieting and bariatric surgery remains the choice for the obese individuals that needs weight loss. However, the most part of patients that lose weight present weight regain, phenomenon named weight cycling. Not all obesity alterations were reverted during weight loss and after a weight regain, some inflammatory markers were worsened when compared with mice that were all time o…
Adipose tissue macrophage infiltration and pro-inflammatory adipokine production contribute to chronic low grade inflammation observed during obesity and it initiates peripheral tissue insulin resistance. The increase in free fatty acids level due insulin resistance in adipose tissue seems to be responsible to the accumulation of free fatty acids in muscle, liver, pancreas and heart resul…
(Only some records are available in English at this moment)
Biometals such as iron, zinc and chromium exhibit important metabolic effects and may alter metabolic homeostasis and/or interfere with the progression of metabolic diseases as diabetes. These biometals must be consumed in the diet, absorbed, stored and distributed appropriately to the target tissues, to perform their biological function, because failures in this process result in deficie…
Ischemia and reperfusion develops when there is an obstruction of blood vessels with subsequent restoration of flow, and its occurs in cases of myocardial ischemia, shock, trauma, hemorrhagic injury, surgery and transplantation. During hepatic ischemia, for example, there is production of free radicals that activate Kuppfer cells (macrophages residing in the liver) resulting in proinflamm…
It has recently been shown that free fatty acids (FFA) can act directly on receptors that act as nutrient sensors signaling sensory (taste) and non-sensory information, such as releasing enteroendocrine and inflammation hormones. The FFA1 / GPR40 was identified as the fatty acid receptor of long chain/medium chain, the FFA2 / GPR43 and FFA3 / GPR41 as a receptor for short-chain fatty acid…
(Only some records are available in English at this moment)
Apelin is an adipokine acting on APJ receptor, regulated by insulin and tumor necrosis factor (TNF)-alpha in adipose tissue. APJ receptor is expressed in intraperitoneal and cultured macrophage. But, there is no data about apelinergic system (apelin/APJ receptor) in macrophage from adipose tissue. If macrophage activity could be modified by apelin, it could have a role in inflammation sta…
| 1 / 1 | Ongoing research grants |
| 10 / 8 | Completed research grants |
| 17 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 29 / 20 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 8 |
| Citations | 42 |
| Cit./Article | 5.2 |
| Data from Web of Science | |
CARIA, CINTIA RABELO E PAIVA; FERREIRA GOTARDO, ERICA MARTINS; SANTOS, PAOLA SOUZA; ACEDO, SIMONE COGHETTO; DE MORAIS, THAINA RODRIGUES; RIBEIRO, MARCELO LIMA; GAMBERO, ALESSANDRA. Extracellular matrix remodeling and matrix metalloproteinase inhibition in visceral adipoSe during weight cycling in mice. Experimental Cell Research, v. 359, n. 2, p. 431-440, OCT 15 2017. Web of Science Citations: 0. (14/10141-3)
DA SILVA, REGINALDO MARQUES; TAKETA MOREIRA, DEBORA KONO; ZARRICUETA, MELINA LUZZI; RABELO E PAIVA CARIA, ANTIA; MACEDO, JULIANA ALVES; MACEDO, GABRIELA ALVES; GAMBERO, ALESSANDRA. The postprandial inflammatory response is attenuated by a dietary structured lipid containing behenic acid. Journal of Functional Foods, v. 58, p. 350-354, JUL 2019. Web of Science Citations: 0. (17/00457-1)
CINTIA RABELO E PAIVA CARIA; CAMILA HENRIQUE MOSCATO; RENATA BORTOLIN GUERRA TOMÉ; JOSÉ PEDRAZZOLI JR; MARCELO LIMA RIBEIRO; ALESSANDRA GAMBERO. NITRIC OXIDE INTERFERES WITH HYPOXIA SIGNALING DURING COLONIC INFLAMMATION. Arq. Gastroenterol., v. 51, n. 4, p. -, Dez. 2014. (10/02991-6)
FERREIRA GOTARDO, ERICA MARTINS; RIBEIRO, GILBERTO DE ALMEIDA; LEITE CLEMENTE, THAYANE RODRIGUES; MOSCATO, CAMILA HENRIQUE; GUERRA TOME, RENATA BORTOLIN; ROCHA, THALITA; PEDRAZZOLI, JR., JOSE; RIBEIRO, MARCELO LIMA; GAMBERO, ALESSANDRA. Hepcidin expression in colon during trinitrobenzene sulfonic acid-induced colitis in rats. WORLD JOURNAL OF GASTROENTEROLOGY, v. 20, n. 15, p. 4345-4352, APR 21 2014. Web of Science Citations: 2. (10/02991-6)
DEOLIVEIRA, CAROLINE CANDIDA; CARIA, CINTIA RABELO E. PAIVA; FERREIRA GOTARDO, ERICA MARTINS; RIBEIRO, MARCELO LIMA; GAMBERO, ALESSANDRA. Role of A(1) and A(2A) adenosine receptor agonists in adipose tissue inflammation induced by obesity in mice. European Journal of Pharmacology, v. 799, p. 154-159, MAR 15 2017. Web of Science Citations: 11. (12/13193-9)
ACEDO, SIMONE COGHETTO; CARIA, CINTIA RABELO E PAIVA; FERREIRA GOTARDO, ERICA MARTINS; PEREIRA, JOSE AIRES; PEDRAZZOLI, JOSE; RIBEIRO, MARCELO LIMA; GAMBERO, ALESSANDRA. Role of pentoxifylline in non-alcoholic fatty liver disease in high-fat diet-induced obesity in mice. WORLD JOURNAL OF HEPATOLOGY, v. 7, n. 24, p. 2551-2558, OCT 28 2015. Web of Science Citations: 7. (11/00518-4)
DE MORAIS, THAIND RODRIGUES; GAMBERO, ALESSANDRA. Iron chelators in obesity therapy - Old drugs from a new perspective?. European Journal of Pharmacology, v. 861, OCT 15 2019. Web of Science Citations: 0. (18/03665-7)
DA SILVA, REGINALDO MARQUES; ZARRICUETA, MELINA LUZZI; TAKETA MOREIRA, DEBORA KONO; DE MORAIS, THAINA RODRIGUES; RIZZARDI, KARINA FERREIRA; PARISOTTO, THAIS MANZANO; DE PADUA GANDRA, RENATA LUANA; ZUIN, JULIA CRISTINA; RABELO E PAIVA CARIA, CINTIA; MACEDO, JULIANA ALVES; et al. STRUCTURED LIPID CONTAINING BEHENIC ACID VERSUS ORLISTAT FOR WEIGHT LOSS: AN EXPERIMENTAL STUDY IN MICE. PHARMANUTRITION, v. 14, DEC 2020. Web of Science Citations: 0. (17/00457-1)
PINTO, LIVIA DE FRAIA; COMPRI, CECILIA MELLETI; FORNARI, JOAO VICTOR; BARTCHEWSKY, WALDEMAR; CINTRA, DENNYS EDUARDO; TREVISAN, MIRIAM; CARVALHO, PATRICIA DE OLIVEIRA; RIBEIRO, MARCELO LIMA; VELLOSO, LICIO A.; SAAD, MARIO J.; et al. The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice. LIVER INTERNATIONAL, v. 30, n. 4, p. 603-610, APR 2010. Web of Science Citations: 22. (07/07735-5)
(References retrieved automatically from State of São Paulo Research Institutions)
MORAIS, Thainá Rodrigues de. Uso dos quelantes como alternativa no tratamento da obesidade : ações sobre o remodelamento do tecido adiposo. Dissertação (Mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas. (18/03665-7)
BATISTA, Simone Coghetto Acedo. Atuação do sistema imune inato e do tecido adiposo e, caracterização farmacológica da pentoxifilina na inflamação hepática. Tese (Doutorado) - Faculdade de Ciências Médicas. Universidade Estadual de Campinas. (11/00518-4)
GAMBERO, Alessandra. Avaliação de compostos de extratos da Anchietia salutaris como possíveis antagonistas de mediadores químicos de processos alérgicos. 62 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências (Campus de Botucatu). Botucatu. (94/03907-4)