Caio Henrique Yokoyama Mazucanti
CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Farmácia-Bioquímica from Universidade de São Paulo (2011) and master's at Pharmacology from Universidade de São Paulo (2013). Has experience in Physiology, focusing on Neorofisiology, acting on the following subjects: neurodegeneration, Alzheimer's disease, streptozotocin and energy metabolism. (Source: Lattes Curriculum)
- Klotho effects on insulin signaling and energetic metabolism in the central nervous system, BP.DR
Abstract
Ageing process was always investigated in C. elegans due to its reproductive cycle (they are hermaphrodites) and short lifespan (they live about 2 months). C. elegans life cycle can be indefinitely expanded once animals enter a phase known as dauer. Several genes altering this stage formation were identified and many codify for proteins associated with the only tyrosine kinase expressed...
- Effects of streptozotocin-induced neurodegeneration in neuro2A cells: in vitro model of neurodegeneration associated to Alzheimer's disease, BP.MS
- Characterization of Alzheimer's model in rats induced by streptozotocin: assessment of marker proteins of the neurodegeneration, of the cytoskeleton and related to the cholinergic system, BP.IC
- Klotho protein and neuronal energy metabolism, BE.EP.DR
Abstract
Aging process was always investigated in C. elegans due to its reproductive cycle (they are hermaphrodites) and short lifespan (they live about 2 months). C. elegans life cycle can be indefinitely expanded once animals enter a phase known as dauer. Several genes altering this stage formation were identified and many of these genes codify proteins associated with the only tyrosine kinase...
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 3 |
| Citations | 15 |
| Cit./Article | 5.0 |
| Data from Web of Science | |
MAZUCANTI, CAIO H.; KAWAMOTO, ELISA M.; MATTSON, MARK P.; SCAVONE, CRISTOFORO; CAMANDOLA, SIMONETTA. Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, v. 39, n. 8, p. 1544-1556, AUG 2019. Web of Science Citations: 0.
CRUNFLI, FERNANDA; MAZUCANTI, CAIO HENRIQUE; MACEDO DE MORAES, RUAN CARLOS; COSTA, ANDRESSA PEREIRA; RODRIGUES, ALICE CRISTINA; SCAVONE, CRISTOFORO; TORRAO, ANDREA DA SILVA. NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance. JOURNAL OF ALZHEIMER'S DISEASE, v. 65, n. 4, p. 1427-1443, 2018. Web of Science Citations: 2.
CARARO-LOPES, MARINA MINTO; YOKOYAMA MAZUCANTI, CAIO HENRIQUE; SCAVONE, CRISTOFORO; KAWAMOTO, ELISA MITIKO; BERWICK, DANIEL CHARLES. The relevance of alpha-KLOTHO to the central nervous system: Some key questions. AGEING RESEARCH REVIEWS, v. 36, p. 137-148, JUL 2017. Web of Science Citations: 13.
(References retrieved automatically from State of São Paulo Research Institutions)
MAZUCANTI, Caio Henrique Yokoyama. Efeitos da proteína Klotho sobre a sinalização de insulina e metabolismo energético no sistema nervoso central.. 2018. Tese (Doutorado) – Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo.
MAZUCANTI, Caio Henrique Yokoyama. Sinalização intracelular desencadeada por concentrações subtóxicas de estreptozotocina em células neuro-2A: modelo in vitro de neurodegeneração associada à doença de Alzheimer.. 2013. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo.