graduate at Odontologia from Universidade de São Paulo Faculdade de Odontologia de Bauru (1993), master's at Farmacologia from Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto (1997) and ph.d. at Farmacologia from Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto (2002). Has experience in Pharmacology, focusing on Clinical Farmacology, acting on the following subjects: elastase-2, analgesia, angiotensin ii, escova dental and flúor. (Source: Lattes Curriculum)
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The individualization of drug prescription has increasingly become the focus of current research in pharmacology so that the adverse effects of drugs are minimized whenever possible. Some studies in the current literature show the relationship that cytochrome P450 polymorphisms, more specifically CYP3A4 and CYP1A2, exert on the metabolism of lidocaine into its main metabolite, monoethyl-g…
Polysomnography is the gold standard assessment for the diagnosis of sleep-disordered breathing. Obstructive sleep apnea (OSA) is a public health problem with serious consequences and its prevalence increases in the cleft lip and palate population. It is estimated that approximately 25% of patients with cleft lip and palate present polysomnographic finding compatible with OSA, which may i…
After a substancial renovation with institutional funding, the animal research facility of the Bauru School of Dentistry will be air-conditioned in order to assure the ideal conditions for the maintenance of animals used in research projects. (AU)
Electric power supply is mandatory to keep equipments working constantly in an animal facility in order to guarantee ideal conditions for the animals. Through this grant a power generator will be purchased so that such ideal conditions will be kept during electric power failures. (AU)
(Only some records are available in English at this moment)
The study about the scarring process allowed the understanding of the molecular events that take place during wound healing. In this process, the local Renin Angiotensin System (RAS), present in the tissues, helps to balance the pro and anti-inflammatory response through bounding of Angiotensin (Ang) II to AT1 and AT2 receptors, and of Ang 1-7 to MAS receptor. In addition, some proteins s…
Periontal disease (PD) comprises a group of lesions that affect periodontal tissues of protection (gingivitis) and support (periodontitis) that may lead to tooth loss. Interactions between microbial pathogens and various systems play a critical role in the development and progression of PD through the release of many inflammatory and immunologic mediators. Recent experiments of our labora…
The aim of any restorative procedure is to reestablish/maintain function, aesthetics, phonetics and periodontal tissues health. In fixed prosthodontics, the main reason of biological failure is caries as 32% of the cases, while periodontal disease cause 4% of such failures, the frequency for endodontic problems. The objective of the present study is to determine whether the blockage of re…
(Only some records are available in English at this moment)
A rare genetic condition known as Treacher Collins Syndrome (TCS) mostly affects the development of the craniofacial region, resulting in a variety of physical abnormalities such lower eyelid colobomas, external ear deformities, and mandibular and zygomatic hypoplasia. These abnormalities impede ribosome biogenesis and neural crest cell (NCC) development during embryogenesis. They are pri…
In the field of dentistry, there is an intense search for better understanding of the relationship between the inflammatory response and bone metabolism, in chronic and infectious diseases scenario. The Renin-Angiotensin System (RAS), in addition to regulating various physiological functions such as those related to blood pressure and cardiovascular system, has been reported as an importa…
The MBGR Orofacial Myology Evaluation Protocol with Scores was developed to diagnose orofacial myology disorders in Portuguese-speaking patients. The MBGR Protocol with Scores used at the Speech-Language Pathology Clinic of the Bauru School of Dentistry has a non-systematized translation into English language that has been previously published. Considering cultural variations between Port…
Non-steroidal anti-inflammatory drugs (NSAIDs) are over-the-counter agents frequently consumed by the population in order to control chronic pain and also acute pain after inflammatory processes. Extraction of lower third molars is recommended for evaluation of the NSAIDs effect since it generates pain, swelling and trismus. Metabolism of NSAIDs is mainly dependent on the family of cytoch…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 23 / 19 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 32 / 19 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 5 / 5 | Completed scholarships abroad |
| 63 / 46 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID