Lauro Thiago Turaça

He holds a bachelor's degree in Biomedicine from the Federal University of São Paulo - UNIFESP (2009). He holds a master's degree (2011) and a doctorate (2018) from UNIFESP for the Molecular Biology program and guidance from prof. joão bosco Pesquero. He is currently a post doctoral student at the University of California - San Diego in the laboratory of prof. Alysson R. Muotri - Dept. of Pediatrics & Cellular Molecular Medicine | UCSD-Sanford Consortium School of Medicine I. He worked for 12 years at the Federal University of São Paulo with genetic diseases involving lysosomal storage diseases and leptin-deficiency obesity. He also developed a treatment with 3D structures of adipose tissue that was able to reverse obesity in leptin-deficient obese mice with cell therapy. For 6 years he worked at the Instituto do Coração (INCOR) with the development of hiPSC-derived cardiomyocytes, electrophysiological analysis and cell therapy in infarcted animals. Currently, as a postdoctoral fellow, he works with neurons derived from reprogrammed stem cells as models for a better understanding of the development of autism. To do this, he is producing mini-brains carrying mutations in the FOXG1 gene. Within the in vitro modeling of autism, he is standardizing electrophysiological data from neurons, molecular signatures through RNAseq Single Cell, mutation correction using CRISPR, and drug screening to identify possible phenotypic reversals. He has experience with induced pluripotent stem cells (IPS), organoids, drug screens, genetic diseases, CRISPR and cell therapy. (Source: Lattes Curriculum)