Ana Carolina Ramos Moreno
CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
FAPESP Young Investigator Fellow at the Department of Microbiology of the Institute of Biomedical Sciences of the University of São Paulo (2016 - current). She is graduated in Pharmacy and Biochemistry at the University of São Paulo (1996-2000), and holds a master's degree (2001-2004) and a PhD (2004-2008) in Microbiology at the Graduate Program in Clinical Analyzes, Faculty of Pharmaceutical Sciences, University from São Paulo. She was a postdoctoral fellow in different areas of health, being Biochemistry of Tumors (melanomas and glioblastomas) at the Faculty of Pharmaceutical Sciences, University of São Paulo (2008-2013); Cancer Cell Biology, at the National Center for Oncological Research (CNIO), Madrid, Spain (2012); Microbiology, focusing on the development of therapeutic vaccines for HPV-associated tumors, at the Institute of Biomedical Sciences of the University of São Paulo (2014-2017). Currently, she is Researcher-Collaborator at the Department of Microbiology of the Institute of Biomedical Sciences of the University of São Paulo. Her research area is based on Microbiology, Immunology and Cell Biology, focusing on the study of pathogen-host cell interaction, bacterial pathogenicity, and immunotherapies for tumors associated with HPV.. (Source: Lattes Curriculum)
- Indoleamine 2,3 dioxygenase in the biology of papillomaviruses-induced tumors: neoadjuvant effects on the immunetherapy of tumors, AP.JP
Abstract
In the last twelve years, solid evidence showed that the enzyme Indoleamine 2,3 dioxygenase-1 (IDO) is an important mediator of immune tolerance. While the similarities between IDO regulatory mechanisms and the molecular signature associated with cervical cancer and other tumors induced by human papillomavirus (HPV), the active role of IDO in these tumors has not been studied. Here, we ...
- Role of indoleamine 2,3 dioxygenase (IDO) in oncogenesis and immunosuppression of tumors associated with human papillomavirus (HPV), BP.MS
Abstract
Human Papillomavirus (HPV) is the etiologic agent of a variety of diseases, such as benign epithelial lesions, genital warts, laryngeal papillomas, and other diseases that are difficult to manage. In recent years, the role of HPV in triggering different types of tumors has been highlighted. It is known that HPV is responsible for more than 99% of cervical tumors, most of the anal tumors...
- Signaling pathways of melanoma regression: focus on melatonin, BE.EP.PD
Abstract
Faithful to its inherent aggressive, melanomas are remarkably resistant to all forms of cancer therapies. The combination of chemotherapy with biomolecules such as IL-2 and IFN-alpha does not appear to be an effective management. However, clinical trials are underway to evaluate new therapeutic strategies. In this context, melatonin (MLT) has been shown to be an excellent adjunct to con...
| 1 / 1 | Ongoing research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 2 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 4 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 6 |
| Citations | 18 |
| Cit./Article | 3.0 |
| Data from Web of Science | |
MORENO, ANA C. R.; PORCHIA, BRUNA F. M. M.; PAGNI, ROBERTA L.; SOUZA, PATRICIA DA CRUZ; PEGORARO, RAFAEL; RODRIGUES, KARINE B.; BARROS, TACITA B.; DE MELO MORAES APS, LUANA R.; DE ARAUJO, ELISEU F.; CALICH, VERA L. G.; et al. The Combined Use of Melatonin and an Indoleamine 2,3-Dioxygenase-1 Inhibitor Enhances Vaccine-Induced Protective Cellular Immunity to HPV16-Associated Tumors. FRONTIERS IN IMMUNOLOGY, v. 9, AUG 22 2018. Web of Science Citations: 0. (16/23189-0, 11/20917-0, 16/00708-1, 15/16505-0, 13/15360-2, 17/25544-4)
SILVA, JAMILE R.; SALES, NATIELY S.; SILVA, MARIANGELA O.; APS, LUANA R. M. M.; MORENO, ANA C. R.; RODRIGUES, ELAINE G.; FERREIRA, LUIS C. S.; DINIZ, MARIANA O.. Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model. CANCER IMMUNOLOGY IMMUNOTHERAPY, v. 68, n. 5, p. 753-763, MAY 2019. Web of Science Citations: 0. (16/14344-1, 14/11073-1, 11/51218-0, 16/00708-1, 13/15360-2, 15/16505-0, 16/11397-7)
OKADA, SABRINA SAYORI; DE OLIVEIRA, EDSON MENDES; DE ARAUJO, TOMAZ HENRIQUE; RODRIGUES, MARIA RITA; ALBUQUERQUE, RENATA CHAVES; MORTARA, RENATO ARRUDA; TANIWAKI, NOEMI NOSOMI; NAKAYA, HELDER IMOTO; CAMPA, ANA; RAMOS MORENO, ANA CAROLINA. Myeloperoxidase in human peripheral blood lymphocytes: Production and subcellular localization. Cellular Immunology, v. 300, p. 18-25, FEB 2016. Web of Science Citations: 5. (10/18498-7, 09/14632-3)
PORCHIA, BRUNA F. M. M.; MORENO, ANA CAROLINA R.; RAMOS, RODRIGO N.; DINIZ, MARIANA O.; DE ANDRADE, LAIS HELENA T. M.; ROSA, DANIELA S.; BARBUTO, JOSE ALEXANDRE M.; BOSCARDIN, SILVIA B.; FERREIRA, LUIS CARLOS S.. Herpes Simplex Virus Glycoprotein D Targets a Specific Dendritic Cell Subset and Improves the Performance of Vaccines to Human Papillomavirus-Associated Tumors. MOLECULAR CANCER THERAPEUTICS, v. 16, n. 9, p. 1922-1933, SEP 1 2017. Web of Science Citations: 2. (09/54599-5, 14/15061-8, 11/51218-0, 11/20917-0, 16/00708-1, 11/08905-7, 15/16505-0)
MORENO, ANA C. R.; CLARA, RENAN O.; COIMBRA, JANINE B.; JULIO, ARIANE R.; ALBUQUERQUE, RENATA C.; OLIVEIRA, EDSON M.; MARIA-ENGLER, SILVYA S.; CAMPA, ANA. The expanding roles of 1-methyl-tryptophan (1-MT): in addition to inhibiting kynurenine production, 1-MT activates the synthesis of melatonin in skin cells. FEBS Journal, v. 280, n. 19, p. 4782-4792, OCT 2013. Web of Science Citations: 10. (09/53800-9, 09/14632-3, 10/15919-1)
CLARA, RENAN ORSATI; ASSMANN, NADINE; RAMOS MORENO, ANA CAROLINA; COIMBRA, JANINE BAPTISTA; NURENBERGER, NADINE; DETTMER-WILDE, KATJA; OEFNER, PETER JOSEF; CAMPA, ANA. Melanocytes are more responsive to IFN-gamma and produce higher amounts of kynurenine than melanoma cells. Biological Chemistry, v. 397, n. 1, p. 85-90, JAN 2016. Web of Science Citations: 1. (10/18477-0)