- Research Grants
FAPESP Young Investigator Fellow at the Department of Microbiology of the Institute of Biomedical Sciences of the University of São Paulo (2016 - current). She is graduated in Pharmacy and Biochemistry at the University of São Paulo (1996-2000), and holds a master's degree (2001-2004) and a PhD (2004-2008) in Microbiology at the Graduate Program in Clinical Analyzes, Faculty of Pharmaceutical Sciences, University from São Paulo. She was a postdoctoral fellow in different areas of health, being Biochemistry of Tumors (melanomas and glioblastomas) at the Faculty of Pharmaceutical Sciences, University of São Paulo (2008-2013); Cancer Cell Biology, at the National Center for Oncological Research (CNIO), Madrid, Spain (2012); Microbiology, focusing on the development of therapeutic vaccines for HPV-associated tumors, at the Institute of Biomedical Sciences of the University of São Paulo (2014-2017). Currently, she is Researcher-Collaborator at the Department of Microbiology of the Institute of Biomedical Sciences of the University of São Paulo. Her research area is based on Microbiology, Immunology and Cell Biology, focusing on the study of pathogen-host cell interaction, bacterial pathogenicity, and immunotherapies for tumors associated with HPV.. (Source: Lattes Curriculum)
In the last twelve years, solid evidence showed that the enzyme Indoleamine 2,3 dioxygenase-1 (IDO) is an important mediator of immune tolerance. While the similarities between IDO regulatory mechanisms and the molecular signature associated with cervical cancer and other tumors induced by human papillomavirus (HPV), the active role of IDO in these tumors has not been studied. Here, we ...
Human Papillomavirus (HPV) is the etiologic agent of a variety of diseases, such as benign epithelial lesions, genital warts, laryngeal papillomas, and other diseases that are difficult to manage. In recent years, the role of HPV in triggering different types of tumors has been highlighted. It is known that HPV is responsible for more than 99% of cervical tumors, most of the anal tumors...
Faithful to its inherent aggressive, melanomas are remarkably resistant to all forms of cancer therapies. The combination of chemotherapy with biomolecules such as IL-2 and IFN-alpha does not appear to be an effective management. However, clinical trials are underway to evaluate new therapeutic strategies. In this context, melatonin (MLT) has been shown to be an excellent adjunct to con...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|