graduate at Faculdade de Odontologia de Bauru from Universidade de São Paulo (1980), master's at Odontology from Universidade de São Paulo (1993) and ph.d. at Endodontology from Universidade Estadual Paulista Júlio de Mesquita Filho (1995). Has experience in Odontology, focusing on Endodontology, acting on the following subjects: canais radiculares, medicamento intracanal, peróxido de hidrogênio, endodontia and clareamento dental. (Source: Lattes Curriculum)
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This randomized study will evaluate in teeth with apical periodontitis the antimicrobial activity and the effect on bacterial products of treatment protocols using intracanal medications with calcium hydroxide [Ca(OH)2], N-acetyl cysteine (NAC) and chlorhexidine (CHX) and their associations. It will be subdivided into 2 subprojects. Subproject 1: It will evaluate the effect of intracanal …
The aim of this study are: a) to quantify endotoxins (EU/mL), lipoteichoic acid (LTA) and microbial load in teeth with primary and secondary endodontic infections, before and after biomechanical preparation and after the use of different intracanal medications; b) to analyze the levels of IL-1, IL-6, IL-10 and TNF-±, Resolvina E1, Resolvina E2 and Lipoxin A4 of the interstitial fluid in …
The objectives of the present study are the following: a) to quantify endotoxins and bacterial load in primary endodontic infections before and after biomechanical preparation (BMP) and use of different intracanal medications (ICMs) in the case of multiple-session therapy; b) to relate levels of endotoxins and cultivable microorganisms to periapical lesion volume by using cone beam comput…
The aim of this study is to evaluate the effects of intracanal medication on microbial biofilms located in resorptions of apical external root surface of extracted human teeth. 90 roots of extracted human teeth with apical external root surface will be submitted to standardized instrumentation. The roots will be randomly divided into 6 groups of 15 roots each (n=15).The roots will be expo…
(Only some records are available in English at this moment)
Molecular events involving periapical lesions are fundamental to both the developmentand repair of these lesions after endodontic treatment. Thus, the aim of this study willbe to evaluate the action of intracanal medications containing calcium hydroxide[Ca(OH)2] and N-acetylcysteine (NAC) on inflammatory and lipid mediators, as well astheir influence on bone markers in patients with prima…
The aim of this study will be to clinically evaluate teeth with pulpal necrosis and apical periodontitis (AP), antimicrobial activity, levels of inflammatory markers (IL-1B and TNF-a), and metalloproteinase (MMPs) before and after the use of intracanal medications based on chlorhexidine. For this purpose, 24 teeth from patients with primary endodontic infection and AP will beselected. The…
The purpose of endodontic treatment in cases of apical periodontitis (AP) is to reducemicroorganisms in the root canal system in order to reduce the periapical inflammatory process, favoring repair in the region. This randomized clinical study aims to evaluate, in teeth with pulp necrosis and apical periodontitis, the levels of lipid mediators - specifically Resolvin D2 and Maresina MaR1 …
(Only some records are available in English at this moment)
This randomized clinical trial will avaluate the inflammatory profile and bone metabolismo in single-rooted teeth with Pulp necrosis and apical periodontitis (AP) after biomechanical preparation and the use of diferente intracanal medications. To achieve this, 45 single-rooted permanent teeth from patients with primary endodontic infection and AP will be selected. The shaping will be perf…
The anatomical complexity and limitation of biomechanical preparation (PBM) make it necessary to use different intracanal medications (MIC) in order to combat resistant microorganisms and intraradicular biofilm. Therefore, this research project aims to trace the microbiological profile, quantify LPS and LTA during endodontic treatment using intracanal medication with chlorhexidine associa…
Calcium hydroxide is the most commonly used intracanal medication. However, its actionthe microbial biofilm is limited. N-acetyl cysteine (NAC), which has been shown to be effective on bacterial biofilms in addition to having action in the resolution of the inflammatory process. At the However, alone, it has a limited effect on the endodontic microbiota. Thus, this study randomized trial …
(Only some records are available in English at this moment)
The aim of this project is to synthesize and characterize simvastatin incorporated nanofibers scaffolds, evaluating its properties and biological response. The experiments will happen in in two phases: The first phase will involve the synthesis and characterization (i.e., morphology, mechanical strength, and drug release) of simvastatin incorporated nanofibers scaffolds using two biodegra…
| 1 / 1 | Ongoing research grants |
| 10 / 4 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 79 / 34 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 95 / 44 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID