- Research Grants
Daniela Luz Hessel da Cunha in research grants and scholarships supported by FAPESP.
Shiga toxins (Stx1 and Stx2) produced by Shiga toxin-producing Escherichia coli (STEC) are potent AB5 type cytotoxins. This toxin family is characterized by a structure formed by two characteristic functional domains: the B subunit forms a pentamer responsible to bind to its receptor, GB3; while the A subunit has a catalytic action, whose mechanism is N-glycosidase, removing an adenine ...
Shiga toxins (Stx1 and Stx2) produced by Shiga toxin-producing Escherichia coli (STEC), are potent AB5 type cytotoxins that cause a hemolytic uremic syndrome (HUS), generally leading intoxicated individuals to death, being an important public health problem. As existing therapies are not effective, a neutralization of Stx toxicity is the most indicated treatment. Antibodies high specifi...
Shiga toxin-producing Escherichia coli is responsible for hemorrhagic colitis and hemolytic-uremic syndrome, which aggravates the condition of the infected patients. The diagnosis of this pathogen is not included in routine laboratories in developing countries. The development of tools for detecting these toxins becomes very relevant to their diagnosis. Antibodies have proven to be an e...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
CUNHA, Daniela Luz Hessel da. Estudo do papel do sistema de captação de fosfato inorgânico (Pst) na fisiologia e patogênese de Streptococcus mutans.. 2011. Dissertação (Mestrado) - Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (08/55389-1)