CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Baixada Santista. Instituto de Saúde e Sociedade (ISS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Full Professor at Federal University of São Paulo (UNIFESP), Campus Baixada Santista. Bachelor in Philosophy (2006) and Psychology (1991) (University of São Paulo), PhD in Psychobiology (University of São Paulo, 1996) and Philosophy (Federal University of São Paulo, 2010) and Post-Doctorate at Institute of Molecular Medicine (IMM) (University of Lisbon, 2019). Current line of research: anxiety, stress, animal models, serotonin, and behavior. Associate editor for Frontiers in Human Neuroscience. Co-responsible for the research group entitled "Neurobiology of stress, anxiety and substance use". Member of the following scientific societies: Sociedade Brasileira para o Progresso da Ciência (SBPC), Sociedade Brasileira de Neurociências (SBNeC) and Sociedade Brasileira de Psicologia (SBP). (Source: Lattes Curriculum)
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Epilepsy is a chronic neurologic disease, characterized by recurrent seizures, which are a result of excessive electrical discharges in a group of brain cells. Potential dysregulation in glutamatergic mechanisms has been a longstanding proposed mechanism in epilepsy. Increases in extracellular glutamate can lead to a buildup of glutamate in the synapse and overactivation of the glutamate …
The concept of stress is based on the observation that different types of stimuli (endogenous or extern to the subject), that might threaten the organism homeostasis, activate a series of physiological alterations named "general adaptation syndrome". The term stimulus (or stressor) corresponds to the events or circunstances that are perceived as aversive by the subject and that generate…
Studies aimed at the neurobiology of anxiety have, during the last years, dedicated considerable attention to the role played by different neurochemical systems on the modulation of defensive responses to aversive stimuli. In this sense, the important role played by serotonin (5-HT) has been emphasized by the clinical efficacy of serotonergic drugs for the treatment of different anxiety…
The concept of stress is based on the observation that any environmental change, either external or internal, can disturb the maintenance of homeostasis/allostasis, causing a series of physiological alterations, the so-called "general adaptation syndrome". The purpose of the stress reaction is to maintain homeostasis/allostasis, which includes physiological reactions such as endocrine act…
(Only some records are available in English at this moment)
Epilepsy is a chronic neurologic disease, characterized by recurrent seizures, which are a result of excessive electrical discharges in a group of brain cells. Potential dysregulation in glutamatergic mechanisms has been a longstanding proposed mechanism in epilepsy. Increases in extracellular glutamate can lead to a buildup of glutamate in the synapse and overactivation of the glutamate …
Among the main constituents of the plant Cannabis sativa are the so-called phytocannabinoids. These substances interact with two kinds of receptors, CB1 and CB2 that are distributed in the nervous system and different organs and peripheral tissues. CB1 receptors are densely expressed on GABAergic interneurons, glutaminergic and serotonergic, in crucial encephalic regions which are respons…
Previous results obtained using Deep Brain Stimulation (DBS) applied to the dorsal portion of the dorsal raphe nucleus (DDR) and to the lateral wings (alDRN) of the same structure in rats showed anxiolytic-like effects of DRD stimulation and panicolytic-like effects of the stimulation of the alDRN in the elevated T-maze model (ETM). In addition, the DBS technique also increased c-Fos prot…
One of the main neurochemical systems related to anxiety and panic responses is the serotonergic system, arising from the Dorsal Raphe nucleus (DR). Previous evidence suggests that the DR is not homogeneous, but a group of distinct neuronal subpopulations, with morphological and functional differences. The serotonergic (5-HT) neurons of the dorsal region of the dorsal raphe (DRD) seem to …
(Only some records are available in English at this moment)
One of the main neurochemical systems related to anxiety and panic responses is the serotonergic system, arising from the dorsal raphe nucleus (DR). Previous evidence suggests that the DR is not homogeneous, but a group of distinct neuronal subpopulations, with morphological and functional differences. The dorsal region of the dorsal raphe (DRD) seems to be critically involved with the re…
| 1 / 1 | Ongoing grants |
| 11 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 17 / 11 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 32 / 19 | All research grants and scholarships |
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