Azair Liane Matos Do Canto de Souza

• Abstract

  Pain is a complex response with social implications that can influence the behavior of individuals socializing with an individual in distress. Understanding and experiencing the emotions of others is known as empathy, a phenomenon observed in humans and other species, including rodents. Studies have shown that mice cohabiting with conspecifics experiencing chronic pain, in pairs or qu…

  Evaluation of a model to study Autism Spectrum Disorder: investigating the role of the interaction between endocannabinoid and oxytocinergic neurotransmissions in anxiety and nociception induced by the neuropathic pain model in male and female mice, BP.IC

• Abstract

  The success of social interaction is a necessary condition for human survival anddepends on the ability to comprehend the intentions and emotions of others. Empathy isan important interpersonal phenomenon that allows understanding and experiencingemotions that the other is feeling. Like human, empathy can be observed in other animalspecies, such as rodents. Recent studies have shown that …

  Assessment of a model to study Autism Spectrum Disorder: Investigation of the role of oxytocin in neuropathic pain-induced nociception in male and female mice., BP.IC

• Abstract

  Social interaction is a necessary factor for human survival and depends on the ability tounderstand the intentions and emotions of others, characteristics associated withempathy, which can be observed in humans and other animals. Living with aconspecific with neuropathic pain increased anxiety and hypernociception in observermice (Ob). The amygdala, one of the structures involved in the m…

  Evaluation of the involvement of amygdala vasopressinergic neurotransmission in nociception-related empathy in male and female mice, BP.MS

(Only some records are available in English at this moment)

• Abstract

  Chronic pain often leads to severe impairment of patient's normal psychological and physical functions. Models of hyperalgesic priming, which can be established with paradigms such as the mouse incision model, provide important insight about the nature of persistent neuronal plasticity that causes these impairments. This model is also an important tool for understanding the molecular mech…

  The role of central nucleus of amygdaloid complex in hyperalgesic priming, BE.EP.PD

• Abstract

  Clinical and experimental evidence suggest an intrinsic relationship between some pain condition and emotional disturbances. Therefore patients in cancer treatment are extremely vulnerable group affective disorders due their pathological condition, or as a consequence of therapies use in treatment. Oxaliplatin (OXL) is a second-line chemotherapy agent, has been used as first-line for some…

  Role of serotoninergic neurotransmission on oxaliplatin-induced neuropathy in mice, BE.EP.DD

• Abstract

  O projeto procura identificar os mecanismos centrais responsáveis pela perda da eficácia dos benzodiazepínicos (BDZ) e daqueles que medeiam à resposta de ansiedade em animais ingênuos e com experiência prévia no labirinto em cruz elevado. Injeções intra-cerebrais de agonistas e antagonistas de receptores BDZ e 5-HT1A serão feitas nos núcleos da rafe, amígdala, hipocampo e septo. Os efeito…

  Efeitos da administração central de ansiolíticos sobre a ansiedade de camundongos reexpostos ao labirinto em cruz elevado, BE.PQ