Abstract
Thiazolidinediones (TZDs) are drugs used to treat type 2 diabetes mellitus (DM2), its mechanism of action occurs by activating PPAR-³ (peroxisome proliferator activated receptors)receptors in the cell nucleus which regulates the expression of genes that affect glucose and lipid metabolism, affects anti-inflammatory activity, decrease blood pressure, cholesterol and triglycerides as well a…