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Alexis de Sá Ribeiro do Bonfim de Melo

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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

PhD in Sciences and Master in Microbiology and Immunology both in Dept. of Micro, Immunology and Parasitology of Federal University of São Paulo (UNIFESP). Bachelor in Marine Biology at State University of São Paulo (UNESP). In recent years I studied the role of host cell signaling pathways responsible for the regulation of actin dynamics during invasion of Trypanosoma cruzi extracellular amastigotes (EAs). I am used to techniques such as confocal microscopy, western blotting and overexpression / depletion of proteins by lentiviral transduction. Currently, i am seeking new mediators of actin cytoskeleton during EA host invasion using biochemical techniques coupled to mass spectrometry. Keywords: Trypanosoma cruzi, extracellular amastigotes, actin cytoskeleton, host cell invasion, host cell signaling (Source: Lattes Curriculum)

Scholarships in Brazil
FAPESP support in numbers * Updated September 14, 2019
Total / Available in English
5 / 3 Completed scholarships in Brazil

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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (3)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications3
Citations17
Cit./Article5.7
Data from Web of Science

BONFIM-MELO, ALEXIS; FERREIRA, EDEN R.; MORTARA, RENATO A.. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. FRONTIERS IN MICROBIOLOGY, v. 9, . Web of Science Citations: 6. (12/21335-8, 11/51475-3)

BONFIM-MELO, ALEXIS; FERREIRA, EDEN R.; FLORENTINO, PILAR T. V.; MORTARA, RENATO A.. Amastigote Synapse: The Tricks of Trypanosoma cruzi Extracellular Amastigotes. FRONTIERS IN MICROBIOLOGY, v. 9, . Web of Science Citations: 2. (11/03357-1, 12/25282-6, 12/21335-8, 11/51475-3)

BONFIM-MELO, ALEXIS; ZANETTI, BIANCA FERRARINI; FERREIRA, EDEN RAMALHO; VANDONINCK, SANDY; HAN, SANG WON; VAN LINT, JOHAN; MORTARA, RENATO ARRUDA; BAHIA, DIANA. Trypanosoma cruzi extracellular amastigotes trigger the protein kinase D1-cortactin-actin pathway during cell invasion. Cellular Microbiology, v. 17, n. 12, p. 1797-1810, . Web of Science Citations: 9. (10/14190-8)

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