- Research Grants
graduate at Licenciatura Plena em Educação Física from Universidade Estadual Paulista Júlio de Mesquita Filho (2003). Has experience in Fitness, focusing on Fitness (Source: Lattes Curriculum)
The study concerning on how cells adapt to distinct mechanical forces, translating physical stimulus in to chemical signals, is such a remarkable issue from mechanobiology, with direct implications on pathophysiology, particularly cardiovascular diseases. Growing evidences point out that redox pathways of cell signaling are fundamental mediators of mechanoadaptive responses. However, th...
Adaptation to mechanical forces is a particularly relevant theme with respect to regulation of the vascular system. Previous data show that constrictive remodeling after injury is redox-mediated. Recently, we showed that protein disulfide isomerase (a redo chaperone from the endoplasmic reticulum) in its epi/pericellular localization (epcPDI) has an anti-constrictive remodeling effect d...
While vascular remodeling is a key determinant of vascular lumen in (patho)physiological situations, its mediators remain poorly understood. Recently, we showed that the endoplasmic reticulum redox chaperone protein disulfide isomerase-A1 (PDI) is markedly upregulated during vascular repair to injury, while its externalized pool (peri/epicellular PDI=pecPDI) counteracts constrictive rem...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|