Abstract
Ohr (organic hydroperoxide resistance) proteins are pivotal players in bacterial response to organic hydroperoxide insults. Our group showed that the Cys based, thiol-dependent peroxidase activity of Ohr underlies the organic hydroperoxide sensitivity phenotype (Cussiol et al., 2003). Elucitation of Ohr crystallographic structure prompts us to propose a mechanism of catalysis, where the t…