Abstract
Dengue virus (DENV) is transmitted by mosquitoes of the genus Aedes and was first isolated in 1943. Almost 400 million people are infected every year with the virus, and half of the world population is subject to the geographical distribution of the virus infection. Until now, five virus serotypes (DENV-1, DENV-2, DENV-3, DENV-4 and DENV-5) were described, all of which are found in Brazil…