Abstract
The ELT is characterized by selective loss of neurons in the CA1 and CA3 subfields of the hippocampus, glial scar, dispersion in the dentate gyrus granule cells and mossy fiber sprouting. Studies to identify signaling pathways during epileptogenesis has shown that some routes involving both processes of neuronal death as neuroprotective agents, such as caspases. Caspases, Bim and Bax over…