graduate at Medicina from Faculdade de Medicina da Fundação ABC (1991), master's at Infectious and Parasitic Illnesses from Universidade Federal de São Paulo (1997), ph.d. at Infectious and Parasitic Illnesses from Universidade Federal de São Paulo (2001) and ph.d. at Doutorado Sanduíche - Depto. de Patologia from The University of Iowa (2000). Has experience in Medicine, focusing on Infectious and Parasitic Illnesses, acting on the following subjects: pseudomonas aeruginosa, sentry, metalo-beta-lactamases, staphylococcus aureus and beta-lactamases. (Source: Lattes Curriculum)
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Antimicrobial resistance (AMR) has been considered one of the main threats to the human race in the 21st century. We are facing an unstoppable fast-forward instance of Darwinian adaptation through natural selection, in which microbes are constantly evolving to survive antimicrobials. As part of their natural behavior, they adapt continuously. They will succeed unless we develop effective …
The approval of new antimicrobials for the treatment of infections caused by gram-negative bacteria producing carbapenemases of classes A, C, and D resulted in the need for laboratory tests that are capable of differentiating classes of beta-lactamases. The immunochromatographic test is based on the antigen-antibody binding for the differentiation of several substances, and its use has sh…
The use and misuse of antimicrobial agents in the human medicine, agriculture and animal husbandry have contributed for the emergence of resistant bacteria. Resistant bacteria have been more commonly detected in the hospital setting; however, multi-drug resistant isolates are also currently found in the community. Several studies have demonstrated that migratory birds play an important ro…
Klebsiella pneumoniae isolates are pathogens frequently acquired infections both in the community and in the hospital environment. The production of carbapenemase mainly KPC type (K. pneumoniae carbapenemase) by this bacterium is a major cause for concern, since strains of K. pneumoniae producing KPC are resistant to most classes of antimicrobials. Thus, the therapeutic options available…
(Only some records are available in English at this moment)
The increasing spread and transmission of antibiotic-resistant S. pseudintermedius from pets (especially dogs and cats) to humans threaten animal and human health worldwide. Most importantly, multidrug-resistant S. pseudintermedius (MDRSP), including the methicillin-resistant S. pseudintermedius (MRSP) strains have emerged as a significant public health problem in veterinary medicine and …
We have witnessed a dramatic increase in infections caused by multidrug- resistant (MDR) bacteria in the last decades. Recently, A. baumannii, P. aeruginosa, and Enterobacterales resistant to carbapenems were elected by WHO as critical pathogens to guide research and development of new antimicrobials [Tacconelli et al., 2018]. The use of new therapeutic strategies to control the emergence…
Growing antimicrobial resistance threatens public health, requiring detailed studies toguide effective interventions(Rogers et. al., 2020). With the high incidence of communicable diseasesand scarce data in low- and middle-income countries (Iskandar et.al., 2021; Styczynski et. al., 2023), Brazil lacks updated information on the genomics of blood infections caused by Enterococcus spp. Thi…
(Only some records are available in English at this moment)
Health-care-related infections caused by multidrug-resistant bacteria (MDR) have often been related to a poorer clinical outcome of hospitalized patients. Since the 1990s, hospital infection control services have encountered different barriers to the containment of MDR microorganisms, mainly due to the absence of efficient antimicrobial therapies against such pathogens. The scarcity of ef…
Cystic fibrosis patients usually become colonized by Burkholderia cepacia complex species (Bcc) species. Part of these patients will become infected along their lifetime what has lead to higher mortality rates. The beta-lactams and trimethoprim/sulfamethoxazole are antimicrobials commonly prescribed for treatment of infections caused by Bcc. However, beta-lactam resistance has already eme…
Carbapenems remain the main therapeutic option for treatment of Acinetobacter baumannii infections. Unfortunately, carbapenenem-resistant A. baumannii have emerged worldwide. Control of outbreaks caused by carbapenem-resistant A. baumannii is rarely achieved due to pathogen´s intrinsic characteristics. Among A. baumannii isolates, the production of ²-lactamase constitutes the most frequen…
(Only some records are available in English at this moment)
Escherichia coli are one of the leading worldwide bacterial pathogens, main responsible by urinary and diarrheal infections. Some group of E. coli isolates are well-known to be more virulent and resistant than others, and in the last years, their genetic characterization raises due to use the Whole-genome sequence. As this micro-organism is also present in the human and animal gut, they a…
| 1 / 1 | Ongoing research grants |
| 16 / 11 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 16 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 40 / 24 | All research grants and scholarships |
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CV Lattes
ORCID