Abstract
The combination of metronidazole (MTZ) and systemic amoxicillin (AMX) for scaling and root planing (SRP) has been shown to be a promising protocol for the treatment of Stages III and IV, Grades B and C periodontitis. However, 30 to 40% of patients treated with this therapeutic approach do not achieve the clinical endpoint for the periodontal treatment suggested by Feres et al. (2012). Bes…