Full Professor of the Department of Biomaterials and Oral Biology at the University of Sâo Paulo School of Dentistry. Visiting Professor at the Oregon Health & Sciences University, EUA (7/2000 - 7/2002) and at The University of Sydney, Australia (8/2010 - 8/2011). His research is focused on the study of dental restorative composites and the development of remineralizing materials containing calcium orthophosphate particles. (Source: Lattes Curriculum)
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Human dentin represents an important calcified tissue in the body and plays significant roles in withstanding masticatory forces. Current restorative therapies focus on the preservation of demineralized dentin structures and the use of materials that can contribute to their remineralization. The distribution of newly formed mineral determines the recovery of mechanical properties in the r…
Calcium silicate-based cements have proven to be an efficient therapy in the context of minimally invasive restorative dentistry. Although they are promising in the dentin remineralization process, there are limitations regarding their indication as a restorative material due to their low mechanical resistance. The objective of the present study is to evaluate the remineralizing potential…
The objective of this project is to develop a resin-based composite containing DCPD particles (dicalcium phosphate dihydrate, CaHPO4.2H2O) to be used in minimally invasive restorations, and evaluate its efficacy in the functional (or biomimetic) remineralization of artificially demineralized human dentin, combined or not with the PILP process. DCPD particles will be synthesized by co-prec…
Calcium phosphate (CaP) nanoparticles functionalization with ethylene glycol dimethacrylete derivatives does not reduce agglomeration. Therfore, alternative strategies are necessary in order to stabilize the nanoparticles and prevent agglomeration, while creating reactive sites to improve the interaction with the composite resin matrix. Citric acid has been used as nanoparticle stabilizer…
In this project, the synthesis of calcium orthophosphate nanoparticles functionalized with ethylene glycol dimethacrylate derivatives (EGDMA, DEGDMA, TEGDMA and TETDMA) will be investigated with the purpose of obtaining particles with low agglomeration and chemical interaction with dimethacrylate-based resin matrices. The ultimate goal is the development of resin composites associating me…
(Only some records are available in English at this moment)
The objectives of this project are to characterize experimental composites containing different volumetric fractions of bioactive glass ceramic (VCB) or dicalcium phosphate dihydrate (DCPD) in relation to calcium release, degree of conversion, mechanical behavior and optical properties and to evaluate, in vitro, the dentin remineralization achieved with these materials. DCPD particles wil…
The development of bioactive materials aims for the greatest possible release of ions. Reducing the viscosity of the resin matrix may enable the incorporation of greater fractions of calcium-releasing particles. The objective of the present study is to evaluate the effect of the BisGMA:TEGDMA ratio and the volumetric fraction of dicalcium phosphate dihydrate (DCPD) incorporated on the phy…
Calcium silicate-based cements have been shown to be an efficient therapy in the context of minimally invasive restorative dentistry. Although they are promising in the dentin remineralization process, there are limitations regarding their indication as a restorative material due to their low mechanical resistance. The objective of the present study is to evaluate the remineralizing poten…
This project aims to determine the amount of wear and surface roughness of resin composites containing dicalcium phosphate dihydrate particles (DCPD, CaHPO4.2H2O) subjected to wear by toothbrushing. Five materials, two of which commercial controls (a resin composite and a glass ionomer cement), a experimental control (composite containing 50 vol% barium glass) and two experimental composi…
Several studies have verified that the replacement of silanized glass particles by particles capable of releasing calcium ions (for example, calcium orthophosphates) promotes severe reductions in the fracture strength of resin composites. This weakening is attributed to the lack of chemical union between the resin matrix and the functional particles and to the lower intrinsic resistance o…
The incorporation of calcium silicate and calcium orthophosphate particles in resin materials has shown to be a promising strategy to promote dentin remineralization. The aim of the present study is to verify the effect of the addition of these particles on the degree of conversion, mechanical properties, optical properties and calcium release of experimental resin materials. In an organi…
(Only some records are available in English at this moment)
The synthesis of dicalcium phosphate dihydrate (DCPD) functionalized with acidic monomers (DEGDMA, citric acid, acrylic acid and methacryloyloxyethyl phosphate) is being investigated to obtain non-agglomerated nanoparticles with high chemical interaction with dimethacrylate-based resin matrices. Although the use of calcium phosphate particles on dental composites is widely studied, the ap…
The integrity of the bonded interface is a key feature in the clinical performance of composite restorations. The stress generated due to composite polymerization shrinkage may lead to interfacial gap formation and residual stress build-up on the tooth structure, increasing the risk of failure over time. This research proposal aims at investigating the influence of cavity dimensions and t…
| 3 / 3 | Ongoing grants |
| 9 / 5 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 26 / 18 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 44 / 31 | All research grants and scholarships |
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CV Lattes
ORCID