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Leandro Ramos Souza Barbosa

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Universidade de São Paulo (USP). Instituto de Física (IF)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Prof. Leandro Barbosa has a degree (2004) and a Ph.D. (2008) in Physics from the University of São Paulo. Has experience in Physics, with emphasis on small angle X-ray scattering (SAXS), transmission electron microscopy (TEM) conventional as well as cryogenic. In recent years he has been dedicated to the study of nanoparticles with cubic structure (cubosomes) for the creation/formulation of Drug Delivery systems. It has also acted in determining the envelope of proteins without resolved structure and in determining the protein structure. It also acts in the study of the effect of denaturing agents on the structure of proteins. Since March 2011 he has been a professor in the Department of General Physics at the Physics Institute of USP, where he coordinates the Laboratory of Biosystems, belonging to the Biophysics Group at FGE. More information can be found at here (Source: Lattes Curriculum)

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FAPESP support in numbers * Updated May 01, 2021
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Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.





Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (16)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

MABANGLO, MARK F.; LEUNG, ELISA; VAHIDI, SIAVASH; SERAPHIM, V, THIAGO; EGER, BRYAN T.; BRYSON, STEVE; BHANDARI, VAIBHAV; ZHOU, JIN LIN; MAO, YU-QIAN; RIZZOLO, KAMRAN; et al. ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. COMMUNICATIONS BIOLOGY, v. 2, . Web of Science Citations: 0. (16/05019-0, 15/15822-1, 12/50161-8, 12/01953-9)

SILVA, NOELI S. M.; SERAPHIM, THIAGO V.; MINARI, KARINE; BARBOSA, LEANDRO R. S.; BORGES, JULIO C.. Comparative studies of the low-resolution structure of two p23 co-chaperones for Hsp90 identified in Plasmodium falciparum genome. International Journal of Biological Macromolecules, v. 108, p. 193-204, . Web of Science Citations: 3. (13/25646-0, 12/50161-8, 14/07206-6, 11/23110-0, 17/07335-9, 15/15822-1, 12/01953-9)

TIROLI-CEPEDA, ANA O.; SERAPHIM, THIAGO V.; PINHEIRO, GLAUCIA M. S.; SOUTO, DENIO E. P.; KUBOTA, LAURO T.; BORGES, JULIO C.; BARBOSA, LEANDRO R. S.; RAMOS, CARLOS H. I.. Studies on the effect of the J-domain on the substrate binding domain (SBD) of Hsp70 using a chimeric human J-SBD polypeptide. International Journal of Biological Macromolecules, v. 124, p. 111-120, . Web of Science Citations: 0. (14/07206-6, 17/07335-9, 15/15822-1, 12/50161-8)

WONG, KEITH S.; MABANGLO, MARK F.; SERAPHIM, THIAGO V.; MOLLICA, ANTONIO; MAO, YU-QIAN; RIZZOLO, KAMRAN; LEUNG, ELISA; MOUTAOUFIK, MOHAMED T.; HOELL, LARISSA; PHANSE, SADHNA; et al. Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death. Cell Chemical Biology, v. 25, n. 8, p. 1017+, . Web of Science Citations: 9. (16/05019-0, 15/15822-1, 12/01953-9)

SERAPHIM, THIAGO V.; ALVES, MARINA M.; SILVA, INDJARA M.; GOMES, FRANCISCO E. R.; SILVA, KELLY P.; MURTA, SILVANE M. F.; BARBOSA, LEANDRO R. S.; BORGES, JULIO C.. Low Resolution Structural Studies Indicate that the Activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis Has an Elongated Shape Which Allows Its Interaction with Both N- and M-Domains of Hsp90. PLoS One, v. 8, n. 6, . Web of Science Citations: 13. (12/50161-8, 10/19242-6, 08/09025-8, 11/23110-0, 12/01953-9)

NANO, NARDIN; UGWU, FRANCISCA; SERAPHIM, V, THIAGO; LI, TANGZHI; AZER, GINA; ISAAC, METHVIN; PRAKESCH, MICHAEL; BARBOSA, LEANDRO R. S.; RAMOS, I, CARLOS H.; DATTI, ALESSANDRO; et al. Sorafenib as an Inhibitor of RUVBL2. BIOMOLECULES, v. 10, n. 4, . Web of Science Citations: 0. (16/05019-0, 15/15822-1, 12/50161-8, 12/01953-9)

GONCALVES, CONRADO DE C.; PINHEIRO, GLAUCIA M. S.; DAHLSTROM, KATHE M.; SOUTO, DENIO E. P.; KUBOTA, LAURO T.; BARBOSA, LEANDRO R. S.; RAMOS, I, CARLOS H.. On the structure and function of Sorghum bicolor CHIP (carboxyl terminus of Hsc70-interacting protein): A link between chaperone and proteasome systems. Plant Science, v. 296, . Web of Science Citations: 0. (16/14228-1, 17/26158-0, 14/00076-0, 17/26058-6, 18/11948-9, 12/50161-8, 15/15822-1)

QUEL, NATALIA G.; PINHEIRO, GLAUCIA M. S.; RODRIGUES, LUIZ FERNANDO DE C.; BARBOSA, LEANDRO R. S.; HOURY, WALID A.; RAMOS, I, CARLOS H.. Heat shock protein 90 kDa (Hsp90) from Aedes aegypti has an open conformation and is expressed under heat stress. International Journal of Biological Macromolecules, v. 156, p. 522-530, . Web of Science Citations: 0. (17/26131-5, 16/05019-0, 15/15822-1, 14/25967-4, 12/01953-9)

ROMANELLI, MAIARA MARIA; DA COSTA-SILVA, THAIS ALVES; CUNHA-JUNIOR, EDEZIO; DIAS FERREIRA, DAIANE; GUERRA, JULIANA M.; GALISTEO, JR., ANDRES JIMENEZ; PINTO, ERIKA GRACIELLE; BARBOSA, LEANDRO R. S.; TORRES-SANTOS, EDUARDO CAIO; TEMPONE, ANDRE GUSTAVO. Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 9, . Web of Science Citations: 0. (18/10279-6, 15/15822-1, 13/07275-5, 15/23403-9)

FEITOSA, VALKER ARAUJO; DE ALMEIDA, VINICIUS CORDEIRO; MALHEIROS, BARBARA; DE CASTRO, RAPHAEL DIAS; SOUZA BARBOSA, LEANDRO RAMOS; PEREIRA CERIZE, NATALIA NETO; RANGEL-YAGUI, CARLOTA DE OLIVEIRA. Polymeric micelles of pluronic F127 reduce hemolytic potential of amphiphilic drugs. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 180, p. 177-185, . Web of Science Citations: 0. (15/15822-1, 14/01983-0)

MALHEIROS, BARBARA; DE CASTRO, RAPHAEL DIAS; LOTIERZO, MAYRA C. G.; CASADEI, BRUNA R.; BARBOSA, LEANDRO R. S.. Design and manufacturing of monodisperse and malleable phytantriol-based cubosomes for drug delivery applications. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, v. 61, . Web of Science Citations: 0. (15/15822-1)

CARDUCCI, FEDERICA; CASADEI, BRUNA RENATA; MARIANI, PAOLO; BARBOSA, LEANDRO RAMOS SOUZA. X-Ray Characterization of Pharmaceutical and Cosmetic Lipidic Nanoparticles for Cutaneous Application. CURRENT PHARMACEUTICAL DESIGN, v. 25, n. 21, p. 2364-2374, . Web of Science Citations: 2. (15/15822-1)

ADAO, REGINA; ZANPHORLIN, LETICIA M.; LIMA, TATIANI B.; SRIRANGANADANE, DEV; DAHLSTROM, KATHE M.; PINHEIRO, GLAUCIA M. S.; GOZZO, FABIO C.; BARBOSA, LEANDRO R. S.; RAMOS, CARLOS H. I.. Revealing the interaction mode of the highly flexible Sorghum bicolor Hsp70/Hsp90 organizing protein (Hop): A conserved carboxylate clamp confers high affinity binding to Hsp90. JOURNAL OF PROTEOMICS, v. 191, n. SI, p. 191-201, . Web of Science Citations: 0. (14/17264-3, 15/15822-1, 12/50161-8)

DA COSTA-SILVA, THAIS ALVES; GALISTEO, JR., ANDRES JIMENEZ; LAULETTA LINDOSO, JOSE ANGELO; BARBOSA, LEANDRO R. S.; TEMPONE, ANDRE GUSTAVO. Nanoliposomal Buparvaquone Immunomodulates Leishmania infantum-Infected Macrophages and Is Highly Effective in a Murine Model. Antimicrobial Agents and Chemotherapy, v. 61, n. 4, . Web of Science Citations: 8. (15/23403-9, 15/15822-1, 13/07275-5, 13/50228-8)

LOTIERZO, MAYRA C. G.; CASADEI, BRUNA R.; DE CASTRO, RAPHAEL DIAS; MALHEIROS, BARBARA; BARBOSA, LEANDRO R. S.. Cubic-to-inverted micellar and the cubic-to-hexagonal-to-micellar transitions on phytantriol-based cubosomes induced by solvents. DRUG DELIVERY AND TRANSLATIONAL RESEARCH, v. 10, n. 6, SI, . Web of Science Citations: 0. (15/15822-1)

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