CV Lattes
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Universidade de São Paulo (USP). Faculdade de Odontologia de Bauru (FOB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto - USP (1995), master's at IMunologia Básica e Aplicada from Faculdade de Medicina de Ribeirão Preto (1998) and doctorate at Imunologia Básica e Aplicada from Faculdade de Medicina de Ribeirão Preto (2003). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: paraciccidioides brasiliensis, p. brasiliensis, cytokines, cd95, apoptosis, paracoccidiodomicosys and il-4. (Source: Lattes Curriculum)
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Evidence shows that obesity is a risk factor for many cancers, but their contribution in human squamous cell carcinoma is unclear. Cholesterol in the tumor microenvironment induces CD8+ T cell functional exhaustion, and inhibition of cholesterol metabolism enhances CD8+ T cell anti-tumor function. Recently, it has been reported increased CD36 expression in tumor infiltrating CD8+ T cells,…
Inflammation is a component of the tumor microenvironment and represents the 7th hallmark of cancer. Although the evidence suggests that inflammation causes cancer, formal proof is still required. It will be important to define which cellular and molecular components are common to all cancer-promoting inflammatory responses, and which are specific to particular tissues and tumor types. Th…
Squamous cell carcinoma (SCC) is one of the most common human cancers worldwide. Recent studies show that regulatory T cells (Tregs) have a critical role in the modulation of an anti- tumor immune response, and consequently the SCC development. Since the accumulation of Tregs at the tumor site is, in part, due to selective recruitment through CCR5 and CCR5-associated chemokines, we invest…
Squamous cell carcinoma (SCC) is the second most common form of skin cancer and is most commonly observed in photo-exposed areas of the body. SCCs localized in the head and/or neck region are often characterized by lymphatic dissemination but the mechanism(s) involved in the progression of this tumor are unknown. Recent studies have shown that there is a direct association between a Th1-r…
(Only some records are available in English at this moment)
Evidence shows that obesity is a risk factor for many cancers, but their contribution in human squamous cell carcinoma is unclear. Cholesterol in the tumor microenvironment induces CD8+ T cell functional exhaustion, and inhibition of cholesterol metabolism enhances CD8+ T cell anti-tumor function. Recently, it has been reported increased CD36 expression in tumor infiltrating CD8+ T cells,…
Experimental and clinical evidence points to a correlation between chronic inflammation and the development of obesity and/or complications arising from this condition. One of the factors that can lead to the development of disorders and diseases is inflammation; when inflammation and obesity occur simultaneously, we observe more significant changes in the immune system. CD4+ T cells part…
Inflammation is a component of the tumor microenvironment and represents the 7th hallmark of cancer. Although the evidence suggests that inflammation causes cancer, formal proof is still required. It will be important to define which cellular and molecular components are common to all cancer-promoting inflammatory responses, and which are specific to particular tissues and tumor types. Pr…
Periodontal disease is a common, complex disease with a variable clinical presentation. The most prevalent form is chronic periodontitis, which can be further characterized by extent and severity (degree of clinical attachment loss). The development of periodontal disease is dependent on the host response and involves Th1, Th2, Th17, and Treg-related cytokines. The discovery of new Th9 an…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 14 / 10 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 21 / 14 | Completed scholarships in Brazil |
| 37 / 26 | All research grants and scholarships |
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