Silvana Regina Perez Orrico

• Abstract

  The aim of this study is to evaluate, in rats, the effect of bisphosphonate therapy on bone repair process and mineralization around osseointegrated implants. For this, 180 rats will be randomly allocated into two groups: the test group, where the animals will receive subcutaneous administration of alendronate once a week, and the control group, where the animals will receive weekly admin…

  Evaluation of bone repair and mineralization in animals submitted to alendronate treatment, AP.R

• Abstract

  Magnesium plays a relevant role on bone tissue and this mineral deficiency results on systemic bone mass loss. However, there is a lack of studies evaluating the relationship of magnesium deficiency and periodontal bone loss. Therefore, this study will investigate the mechanisms involved on periodontal bone loss in rats with induced magnesium deficiency. For that purpose, this study compr…

  Evaluation of the parameters associated to periodontal bone loss in animals submited to dietary magnesium intake deficiency, AP.R

• Abstract

  This study will be aimed in the evaluation of the period of time after the cessation of the bisphosphonate therapy necessary to the reestablishment of the bone turnover. Seventy rats will be divided into 2 groups: control group (n = 10) and test group (n = 60). The control group will receive weekly subcutaneous injections of a placebo while the test group, alendronate once a week. After 9…

  Bone turnover assessment after bisphosphonate treatment cessation., AP.R

(Only some records are available in English at this moment)

• Abstract

  Periodontitis is a multifactorial inflammatory disease initiated and maintained by microorganisms of the dental biofilm, which affects the supporting structures of the teeth. In spite of its infectious nature, behavioral, genetic, and host-related factors ultimately determine the severity, susceptibility, and progression of the disease. The relevant role played by Mg on bone metabolism ra…

  Influence of magnesium deficiency in the diet on mandibular bone density and on induced periodontal disease: evaluation by computed microtomography, BP.IC
• Immunohistochemical evaluation of the factors associated to bone formation and resorption in animals submitted to magnesium intake deficiency on diet., BP.IC
• Effect of dietary magnesium reduction on bone around osseointegrated titanium implants. Study in rats., BP.DR