- Research Grants
graduate at Ciências Biologicas from Centro de Ensino Superior de Juiz de Fora (2008). Has experience in Physiology, focusing on Comparative Physiology, acting on the following subjects: murídeos, superovulação, heterose, embriões, sinalização celular, gene ob, obesidade and leptina. (Source: Lattes Curriculum)
The retina, through melanopsin-positive ganglion cells, constitutes the main input of light information to entrain the mammalian central oscillator, the suprachiasmatic nuclei (SCN). The clock molecular mechanism in SCN is responsible for the generation of rhythmic function, which is transmitted to other organs, allowing the whole organism to align the internal time in harmony with the ...
In mammals, there is a network of central and peripheral circadian clocks, regulating behavioral and biochemical processes in the organism. Light information travels through the retina and activates a series of opsins, among which is the photopigment melanopsin (OPN4) present in intrinsically photosensitive cells (ipRGCs) which constitute about 2% of the ganglion cell layer. Melanopsin ...
Daily cycles of light and temperature are two major signals of environmental time for the organisms. It is important to emphasize, however, that ambient temperature does not alter body temperature of endothermic animals, as the inner temperature is controlled by the master clock, through light signaling via the retina. As the suprachiasmatic nuclei are entrained by the light-dark cycles...
The pigment cells of heterothermic vertebrates respond with pigment migration to a variety of agents, including ETs and SRTXs. In teleost fish, ETs e S6c induce pigment aggregation in melanophores, this effect is blocked by ETb antagonists (Fujii et al., 1993; Hayashi et al., 1996; Ramanzini et al., 2006). In amphibians, ET-3 is more potent than ET-1 and ET-2 in promoting pigment granul...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
BORGES, Maria Nathália de Carvalho Magalhães Moraes Figueira. Efeito da endotelina sobre a expressão gênica das melanopsinas (Opn4x e Opn4m) e do receptor de endotelina, subtipo ETc, em melanóforo de Xenopus laevis. 2010. Dissertação (Mestrado) - Instituto de Biociências. Universidade de São Paulo (USP). São Paulo.
BORGES, Maria Nathália de Carvalho Magalhães Moraes Figueira. Efeito da luz e endotelina no mecanismo molecular do relógio em melanóforos de Xenopus laevis. 2014. Tese (Doutorado) – Instituto de Biociências. Universidade de São Paulo (USP). São Paulo.