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Fábio Rogério de Moraes

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Ministério da Agricultura, Pecuária e Abastecimento (Brasil). Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA). Embrapa Informática Agropecuária  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Bachelor in Physics from the State University of Campinas (UNICAMP). PhD from the Genetics and Molecular Biology Departament of the Institute of Biology, also from UNICAMP. I have working experience in Biophysics, Molecular Biology, Structural Computational Biology and Bioinformatics. In my PhD, I studied the physico-chemical and structural basis of protein-protein association by using tools from relational databases (MySQL), statistical and machine learning algorithms (neural networks, SVM, random Forest, Bayesian Networks, LDA, etc), including case studies by protein-protein Docking and protein Molecular Dynamics. In the current postion, as a research assistant in the Physics Departament and Multiuser Center for Biomolecular Innovation from the Instituto de Biociências, Letras e Ciências Exatas (IBILCE) da UNESP, I am responsible of the maintenance and operation of a Nuclear Magnetic Resonance spectrometer of 600 MHz, equipped with a triple resonance cryoprobe. I participate in studies of protein-ligand interaction by means of Saturation Transfer Difference effect using NMR (STD-NMR). By using the protein structure and the binding epitopes from STD-NMR, protein-ligand docking and molecular dynamics are carried out in order to get insight in the molecular recognition process. Also, in another research line, NMR-based metabolomics/metabonomics studies are carried out in order to have a more clear picture of the metabolic response of cells under different stimulus. By using statistical and machine learning tools, coupled with metabolic network analysis, it is possible to suggest important pathways affected by mutations, infection or specific treatments. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (2)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

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DE MORAES, FABIO R.; NESHICH, IZABELLA A. P.; MAZONI, IVAN; YANO, INACIO H.; PEREIRA, JOSE G. C.; SALIM, JOSE A.; JARDINE, JOSE G.; NESHICH, GORAN. Improving Predictions of Protein-Protein Interfaces by Combining Amino Acid-Specific Classifiers Based on Structural and Physicochemical Descriptors with Their Weighted Neighbor Averages. PLoS One, v. 9, n. 1, . Web of Science Citations: 4. (09/03108-1, 09/16376-4)

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