Abstract
Naive CD4+ and CD8+ T cells develop into Th9 and Tc9 cells in the presence of IL-4 and TGF-b. Tc9 cells support Th2-mediated experimental lung inflammation by increasing the symptoms. Recently, it was demonstrated that animals fed with a rich-fiber diet were protected from experimental lung inflammation due to the modulation of short chain fatty acid (SCFA)-producing microbiota. Additiona…