CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Odontologia (FOAr) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Odontologia Integral from Universidade Estadual Paulista Júlio de Mesquita Filho (1988), master's at Morphology from Universidade Federal de São Paulo (1995) and doctorate at Morphology from Universidade Federal de São Paulo (2000). He is currently orientador - pós-graduação em morfologia at Universidade Federal de São Paulo. Has experience in Morphology, acting on the following subjects: morfometria, imuno-histoquímica, apoptose, biocompatibilidade and materiais endodônticos. (Source: Lattes Curriculum)
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Periodontitis (P), triggered by subgingival bacterial accumulation, causes the periodontal tissues degradation (gingiva, cementum, periodontal ligament and bone alveolar). Bone loss is considered as hallmark of progression of P. Therefore, the bone loss resulting of P is closely associated with osteoclast formation, activity and survival. Cytokines such as interleukin-1 (IL-1), IL-6, tumo…
The degradation of tissues of the eruptive pathway occurs during tooth eruption, including the lamina propria and bone located between tooth germ and oral mucosa. The eruptive pathway degradation depends on a complex cascade of cellular and molecular events that occur at specific sites and time. It is known that TNF-± and IL-1 are involved in osteoclastogenesis and activation of metallopr…
Bone tissue, a specialized connective tissue, is constituted by different cell types (lining cells, osteoblasts, osteocytes and osteoclasts) and a mineralized extracellular matrix. The periodontium comprises the structures responsible for maintaining the tooth in the maxillary and mandibular bones and consists of: cementum, periodontal ligament, alveolar bone and gingiva. The alveolar pro…
Estrogen plays important functions on osteocytes viability and its deficiency leads to decrease in the number of these cells and subsequent increase in bone resorption. There are evidences that autophagy also plays important roles on osteocyte viability and that estrogen plays a role in the regulation of autophagy in some cell types; in osteocytes, however, this mechanism is still unknown…
(Only some records are available in English at this moment)
Periodontitis (P) and type 2 diabetes mellitus (T2DM) are complex and multifactorial chronic diseases, characterized by a hyper-inflammatory state. The immunoinflammatory state promotes the recruitment of specific cells that release mediators, such as interleukin-1² (IL-1²), IL-6, IL-7, tumor necrosis factor-alpha (TNF-±), and matrix metalloproteinases (MMPs). Therefore, the modulation of…
Periodontitis (P) is a multifactorial disease triggered by the host response to the accumulation of bacteria in the gingival sulcus, which can be influenced by several factors, among them systemic, environmental, trauma and drugs. The periodontitis progression is mediated by some bioactive agents such as interleukins (IL), matrix metalloproteinases (MMP) and transcription factors that int…
Periodontal disease (PD), triggered by subgingival bacterial accumulation, causes the periodontal tissues degradation (gingiva, cementum, periodontal ligament and bone alveolar). Bone loss is considered as hallmark of progression of PD. Therefore, the bone loss resulting of PD is closely associated with osteoclast formation and cytokines released by cells of inflamed periodontal. Cytokine…
Repair sealers must have ideal physicochemical and biological properties as well as the potential for osteoinduction. MTA is considered the most effective material in tissue repair due to good sealing ability, biocompatibility, and bioactivity. New MTA-containing materials have been launched on the market in an attempt to improve the physicochemical properties of the White MTA (W-MTA). Th…
The aim of this study will be to evaluate the systemic response, biocompatibility, and bioactive potential and physicochemical properties of a bioceramic-based intracanal medication, BIO-C TEMP in comparison with the Calen paste. Polyethylene tubes will be filled with BIO-C TEMP or Calen paste and will be implanted in the dorsal subcutaneous of sixty male adult rats distributed into 3 gro…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 5 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 15 / 12 | Completed scholarships in Brazil |
| 23 / 19 | All research grants and scholarships |
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