Bachelor in Dentistry at Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP (1993) Master in Oral and Dental Biology and Pathology at Universidade Estadual de Campinas UNICAMP (1995) PhD in Oral and Dental Biology and Pathology at Universidade Estadual de Campinas UNICAMP (1997) Post-doc at University of Turim, Italy (1997-1999) Medical Mycology Post-doc at Universidade Federal de Belo Horizonte UFMG, Brazil (2000-2002) Mycology and Molecular Biology Formation in Management in Higher Education (INPEAU/UFSC/Interamerican Organization for Higher Education and visit to University of Laval)- 2015 Visitor Researcher at Hong Kong University, Faculty of Dentistry (2010)- Biofilms and confocal microscopy Invited visitor researcher at The Leibniz Institute for Plasma Science and Technology (Germany, 2016 Applications of Plasma) Technic-scientific visits to Instituto Carlos Malbran (Buenos Aires, 2003 Antifungals), University of Oxfor, Department of Education (UK, 2014 English as a medium of instruction), Kansas State University (US, 2015 Studies in Leadership) Coordinator of UNESP Leadership and Management School (2021-2016) Former Coordinator of Oral Biopathology Graduate Program (2007-2013) Full Professor at Institute of Science and Technology, São Paulo State University/Unesp from 2002 in undergraduate and graduate courses (Applied Microbiology) Advisor at Unesp Office for Graduate Studies (2021- ) Coordinator of Area (Health II) at FAPESP (The São Paulo Research Foundation) Researcher at CNPq (National Counsel of Technological and Scientific Development, Brazilian Ministry of Science and Technology) Coordinator of Research Group Alternative Methods for Microbial Control Associate Editor for BMC Complementary Medicine and Therapies and member of the Editorial Advisory Board, Journal of Investigative and Clinical Dentistry Research interests: Candida, caries, biosecurity, opportunistic microorganisms, infection control and development of alternative methods. Experience in human resources formation: 4 post-doc, 12 PhD, 10 Masters and 72 undergraduation students in scientific activities. Ad hoc advisor/reviewer: FAPESP , CNPq, Arch Oral Biol, Future Microbiol, Molecules, BMC Infectious Dis, BMC Oral Health, Acta Odontol Latinoam, Braz Oral Res, Mycoses, Mycopathol, Microbial Pathog, Rev Instit Adolfo Lutz, Eur J Dent, Int J Diabetes Mellitus, Gerodontol, African J Biotechnol, Rev Instit Med Trop São Paulo, Braz J Microbiol, Rev UNESP, e Oral Dis. (Source: Lattes Curriculum)
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This proposal aims to investigate the use of low temperature atmospheric pressure plasma (LTAPP) in Dentistry. The general aim is to develop protocols for the application of plasma and plasma activated liquid in vivo and ex vivo for diseases of dental interest and a portable equipment for clinical use. The specific aims are to develop effective protocols to the following relevant patholog…
Some infectious diseases represent a great challenge in Dentistry due to their increasing prevalence, low number of therapeutic options and/or increase in the antimicrobial resistance. Considering that the searching for new therapies is highly needed, this project aims to prospect innovative therapeutic alternatives, evaluating the applicability of low temperature atmospheric plasma (LTAP…
The searching for new therapeutic alternatives for oral candidosis is of utmost importance. In this context, the aim of this study will be to evaluate the in vitro antifungal effectiveness of the phenolics enriched fraction (FE) of Buchenavia tomentosa leaves and isolates substances galic acid, corilagin, kaempferol and vitexin detected in the bioactive crude aquous extract of B. tomentos…
Defining the oral microbioma of infants and how it changes over time would be of great importance for the prevention, diagnosis and treatment of oral diseases at an early stage. The aim of this study is to evaluate the microbial colonization of children attending an oral health program for infants at 6, 12, 18 and 24 months and the microbial diversity associated with diet, oral hygiene, p…
(Only some records are available in English at this moment)
The antimicrobial, anti-inflammatory and tissue repair-inducing actions promoted by reactive species generated by the plasma and its low toxicity are promising characteristics that can be applied in the treatment of diseases in the dental areas. In this context, this proposal aims to investigate the applications of cold atmospheric pressure plasma (LTAPP) in Dentistry. The general objecti…
This work plan aims the characterization and optimization of a cold plasma jet operating in atmospheric pressure for microbial sterilization and application in live tissues. For achieving the goal the development of a robust, versatile, easily operated and totally safe device is needed in order to be used in patients without risk of electrical shock or burning. The group of plasma in Guar…
The aim of this project is to evaluate the association between the ascorbic acid and cold atmospheric pressure plasma (CAP) for the treatment of oral candidiasis. The study begin with in vitro experiments to establish the ideal conditions of interaction. The effect of association of CAP and different concentrations of L-ascorbic acid will be evaluated on planktonic cells of reference stra…
Oral Mucositis is a clinical condition that frequently affects patients under antineoplasic therapy for head and neck cancer. The disease is correlated with oral mucosa ulcerations and intense pain, odynophagia, increase in the risk for infections, use of antibiotics and period of hospitalization. The correlation among Oral Mucositis, fungemia and the potential of systemic fungal dissemin…
The main objective of the present study is to evaluate the application of low temperature plasma at atmospheric pressure (LTAPP) for the control of cariogenic biofilms. To this end, the effective physical parameters of LTAPP against polymicrobial biofilms composed of combinations of the species Streptococcus mutans, Streptococcus gordonii, Streptococcus sanguinis, Lactobacillus casei, Can…
(Only some records are available in English at this moment)
The aim of this study is to evaluate the application of low temperature atmospheric pressure plasma (LTAPP) in the treatment of chemotherapy-induced mucositis. Commercially available plasma generating equipment (Kinpen") will be used for this, which is available at Indiana School of Dentistry. Organotypic models of oral mucositis will be treated with LTAPP for the determination of an effe…
Candida albicans is an opportunistic fungus that may cause disease in the presence of predisposing factors, leading to local or invasive candidiasis. The aim of this study is to evaluate if the pretreatment with vitamin C could improve the antifungal effect of low temperature plasma (LTP) against C. albicans, which could lead to reduced LTP exposure time. For this, a reconstituted oral ti…
The aim of this study is to evaluate the application of low temperature plasma atatmospheric pressure (LTAPP) in the control of cariogenic biofilms. A commerciallyavailable plasma-generating equipment (Kinpen®) will be evaluated at IUPUI. Physicalparameters of LTAPP effective against polymicrobial biofilms composed ofcombinations of the species Streptococcus mutans, Streptococcus gordonii…
The purpose of the research project to be developed during the international internship is to investigate the impacts of cystic fibrosis (CF) on the salivary composition of pediatric patients by salivary proteome analyses. Hundred children aged from 3 to 20 years will be included in the study and will be divided into 3 groups: G1- 25 pediatric patients with CF, CFTR mutation detected and …
The purpose of this study will be to investigate the effects of hydroxyurea (HU) used in the treatment of sickle cell anemia (SCA) on the oral microbioma. Forty children aged 6 to 14 years divided into 4 groups: G1 (10 patients with SCA at the beginning of treatment with HU), G2 (10 patients with SCA and under treatment with HU for 3 months), G3 (10 patients with SCA and under treatment w…
| 1 / 1 | Ongoing research grants |
| 16 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 53 / 22 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 77 / 34 | All research grants and scholarships |
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