- Research Grants
Francisco Fávaro de Assis in research grants and scholarships supported by FAPESP.
The research proposal aims to prepare a small library of analogues of Glibenclamide in order to be in vivo evaluated as anti-hyperglicemic agents. Analogues containing the piperazine moiety as a spacer between the amide and phenylsulfonil groups of Glibenclamide will be prepared. The use of flow chemistry methodology will be considered for scaling up the synthesis. (AU)
We propose the synthesis of new tetrabromobacteriochlorins adapting the methodology developed by Lindsey and coworkers. For the preparation of the desired structures are required several reaction steps into a linear pathway which includes the synthesis of different types of functionalized pyrroles, to more complex structures which will serve as precursors in the synthesis of desired bac...
(Only some records are available in English at this moment)
This project is about the synthesis of novel di-hydrocoumarin-C-aryl glucosides as potential anti-hyperglycemic agents for the treatment of type 2 diabetes. Such compounds can be synthesized by means of a asymmetric photochemical beta-arylation of Michael acceptors, using chiral Lewis acids. If this methodology does not provide the desired compounds, a secondary approach is the use of t...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|