- Research Grants
Graduated in Biology at the State University of Campinas (2010), master's (2013) and PhD (2018) in Cell and Structural Biology from the University of Campinas. Studies the involvement of immune molecules on glial reaction and synaptic plasticity after lesions in the CNS / PNS interface. (Source: Lattes Curriculum)
Peripheral nerve lesions are followed by an increase in expression of immune molecules, such as the Major Histocompatibility Complex Class I (MHC-I). The MHC-I upregulation is directly related to the synaptic plasticity process, glial cell activity modulation and functional recovery. Knockout mice for the MHC-I obligatory chain ²2 microglobulin (²2m), show increased reduction in synapti...
The interaction between motoneurons and the circunjacent microenvironment has a crucial function for survival and regulation of functional state and synaptic connectivity. After trauma, indicative changes of dysfunction and degeneration initiate proximal and distal to lesion, however, the regenerative capacity of nervous system result in compensatory structural and functional remodeling...
The interaction between motoneurons and glial cells has a crucial role for survival, regulation of functional state and synaptic connectivity in the spinal cord. Understanding the basic functions of glial cells and motoneuron interaction will contribute to the development of new strategies in order to promote regeneration after injury. After lesion, glial cells also undergo a series of ...
For analysis of the progression of regeneration in the central and peripheral nervous system usually are used techniques from histological sections that provide a two-dimensional image of the regenerating axons, showing only fragments, and may thus lead to misinterpretations. In order to overcome this obstacle, the tetrahydrofuran (THF)-based clearing technique was proposed. Through thi...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
CARTAROZZI, Luciana Politti. Utilização do selante de fibrina combinado com células tronco mesenquimais no reparo de nervos periféricos através da técnica de tubulização= : Use of fibrin sealant combined with mesenchymal stem cells in the repair of peripheral nerves through tubulization technique. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). (11/02889-0)
CARTAROZZI, Luciana Politti. Immunomodulatory mechanisms of mesenchymal stem cells in glial reactivity and correlation with regenerative capacity after lumbar root axotomy : Estudo dos mecanismos imunomoduladores exercidos pelas células tronco mesenquimais sobre a reatividade das células gliais e correlação com a capacidade regenerativa após axotomia de raízes lombares. Tese (Doutorado) - Universidade Estadual de Campinas, Instituto de Biologia. (13/16134-6)