Full Professor of the Nursing School of University of Sao Paulo. Graduated at Nursing from Universidade Federal de Sao Paulo (1987), master's at Biochemistry from Universidade Federal de Sao Paulo (1993) and PhD at Health Scienses, Nephrology, from Universidade Federal de São Paulo (1998). Vice Dean, Vice Mayor of the Campus of Health and Law and Coordinator of the International Cooperation Commission of the School of Nursing of the University of Sao Paulo . Experience in Nursing and the research field is the pathophysiology of acute renal injury and chronic kidney disease, non-pharmacological therapies, antioxidants, radiocontrast and polymyxin B. (Source: Lattes Curriculum)
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Noncommunicable Diseases (NCDs) are the biggest cause of deaths worldwide. Majority of premature deaths from NCDs are linked to tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol. NCDs, like Chronic Kidney Disease (CKD) and Diabetes, are preexisting clinical conditions that are risk factors for complications like drugs nephrotoxicity, as Contrast Nephropathy (CN).…
The contrast-induced nephropathy (CIN) is directly linked to chronic diseases that compromise the oxygenation in the region of the renal medulla. Chronic hyperglycemia changes a hemodynamic in the microvasculature, endothelial dysfunction and activation of inflammatory processes and oxidative injury, incurring decreased in glomerular filtration rate (GFR). The aim of this study is to inve…
(Only some records are available in English at this moment)
Acute kidney injury (AKI) is clinically defined as a 0.3mg/dL or 1.5-fold increase in baseline serum creatinine in 48 hours or a reduction in urinary output to less than 0.5mL/Kg during 6h. Ischemic AKI (iAKI) is predominantly triggered by renal hypoperfusion related to events such as kidney transplantation, unfavorable hemodynamic conditions and even sepsis. Experimental studies demonstr…
The presence of Diabetes Mellitus (DM) increases the susceptibility to acute renal injury caused by ischemia and reperfusion (I / R), which in clinical practice may coexist in diabetic patients under critical conditions. I/R and DM share common physiopathological mechanisms, involving dynamic physiopathology comprehending inflammation and oxidation. Curcumin, present in Curcuma longa L., …
Chronic hyperglycemia promotes the installation of iodinated Contrast-Induced Nephropathy (CIN). Diabetes Mellitus (DM) and CIN involve mechanisms coincident oxidative damage and induction of protective enzymes and cellular adaptation as coenzyme Q10 (CoQ10). The aim of this study is to evaluate the role of CoQ10 on renal function and oxidative profile in diabetic rats submitted to the NI…
(Only some records are available in English at this moment)
| 17 / 10 | Completed research grants |
| 13 / 6 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 31 / 16 | All research grants and scholarships |
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