CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
I am a Pharmacy graduate from University of Sao Paulo (2001) and have a Master of Science degree and a PhD degree in Cell and Molecular Biology at the same University. I have experience working with protein traffic, mast cell secretion, and generation of transgenic mouse models . During my Post Doctoral Research at University of Sao Paulo (Ribeirão Preto Medical School) and I was focused on the role of proteases and their inhibitors on HNSSC. Recently worked as a collaborative lecturer at FMRP-USP and as a scientist at CREDERE LifeSciences. (Source: Lattes Curriculum)
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Head and Neck Carcinomas (HNSCC) comprise predominantly squamous cell carcinomas of the oral cavity, larynx and pharynx. HNSCCs are the sixth most common type of cancer and affects over 550.000 patients annually. Matriptase, a type 2 transmembrane serine protease, induces malignant transformation when expressed in epithelial stem cells. Proteolytic activation of pro-HGF and the PI3K-Akt-m…
Head and neck cancer comprises predominantly squamous cell carcinomas and affects the oral cavity, larynx, and pharynx. Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with 550.000 new cases every year. Matriptase, a type II transmembrane serine protease, induces malignant transformation when expressed in epithelial stem cells. It has been recently …
Mast cells (MCs) are multifunctional immune cells implicated in inflammation, allergy, tissue repair and angiogenesis. Along with neurons, melanocytes, endocrine and exocrine cells, as well as other immune cells, MCs are specialized secretory cells, which presents regulated secretion. The regulated secretory pathway requires the sorting of proteins to a specific route destined to secretor…
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Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Matriptase, a type II transmembrane serine protease, induces malignant transformation through proteolytic activation of pro-HGF and PAR-2, which leads to activation of PI3K-AKT-mTOR and NFºB signaling, respectively, in epithelial stem cells. Lympho-Epithelial Kazal-Type-related Inhibitor (LEKTI) was s…
| 4 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
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