Abstract
The immune system is able to eliminate infectious process. However, some pathogens, as Leishmania major, Mycobacterium tuberculosis, HIV e Mycobacterium leprae, might elicit latent infections and chronic disease. Significant importance has been given to a distinct subset of T CD4+CD25+ cells, also termed as T regulatory cells (Tregs), which potently abrogate immune response to self or tum…