- Research Grants
graduation at Ciências Biológicas - Bacharelado from Universidade Estadual de Campinas (2009), master's at Genetics from Universidade Estadual de Campinas (2012) and doctorate at Genetics from Universidade Estadual de Campinas (2016). Has experience in Genetics, focusing on Human and Medical Genetics, acting on the following subjects: pedf, retinopathy, sickle and icam. (Source: Lattes Curriculum)
Although sickle cell anemia results from homozygosity for a single mutation at position 6 of gamma-hemoglobin locus, this disease presents high heterogenity in phenotype, so that different patients may have significantly different clinical outcomes. Virtually all organs may be affected by vascular occlusion, with emphasis on the Central Nervous System (CNS), where are observed transient...
Sickle cell disease are characterized by the presence of hemoglobin S (HbS), which favors the formation of sickled red cells through its polymerization in deoxygenated state. Homozygous individuals for the allele of hemoglobin S are affected by sickle cell anemia, while heterozygotes individuals may develop other sickle cell diseases (especially hemoglobin SC) or on sickle cell trait (H...
Although sickle cell anemia (SCA) results from the homozygosity of a single mutation in amino acid 6 of the ²-globin locus, this disease presents high phenotypic heterogeneity, so that different patients may have significantly different clinical outcomes. Vascular occlusion occurs systemically, and transient ischemic attacks, stroke and cerebral hemorrhage affect approximately 25% of pa...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
CRUZ, Pedro Rodrigues Sousa da. Avaliação das variações no número de cópias (CNVs) na susceptibilidade ao acidente vascular cerebral em pacientes com anemia falciforme = Copy number variations (CNVs) in the assessment of stroke susceptibility in patients with sickle cell anemia. 2016. Tese (Doutorado) – Universidade Estadual de Campinas, Instituto de Biologia.
CRUZ, Pedro Rodrigues Sousa da. Análise bioquímica e genética das vias de adesão celular e crescimento vascular : associação com o desenvolvimento de retinopatia falciforme. 2012. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).