Bruno Vilela Muniz

• Abstract

  One of the great achievements in dentistry was the development of local anesthetics, which allow the accomplishment of painless dental treatment in most cases. However, administration of the anesthetic involves puncture of the tissue with needles and injection of the solution, which are painful procedures and strongly induce stress to patients. To minimize this discomfort, topical anesthe…

  Thermoreversible hydrogel containing tetracaine loaded in nanostructured lipid carriers for topical intranasal delivery, BP.PD

• Abstract

  The local anesthetic toxicity has been shown in many cell types and may be associated to the production of proinflammatory cytokines. Articaine has been implicated in many cases of paresthesia after inferior alveolar nerve block; this occurrence seems to be concentration-dependent. The association to carriers (objective of the project "temático" associated), such as liposomes, has been sh…

  Modulatory effects of 2%, 3% and 4% plain articaine and articaine encapsulated into liposomes on citocine production by human gingival fibroblasts., BP.MS
• Modulatory effects of articaine 4%, with or without liposomes on cytokine production in human oral epithelial cells., BP.IC

(Only some records are available in English at this moment)