Abstract
Spermatogonial stem cell (SSC) niche are specific regions of the testes which regulate stem cell properties, such as, self-renewal, differentiation, apoptosis, quiescence and pluripotency. The regulation of the SSC niche is essential to avoid accumulation of SSC (seminoma), when self-renewal is favored, or spermatogenesis depletion when differentiation is predominant over self-renewal. Ch…