Education: Oral and Maxillofacial Surgery (OMFS), School of Dentistry at Ribeirão Preto, University of Sao Paulo (USP) (2000-2002) and General Hospital "Vila Penteado" (2003-2005) Inhalation Conscious Sedation (2009), School of Dentistry, Federal University of Rio de Janeiro (UFRJ) Masters and Doctorate in OMFS, School of Dentistry at Ribeirão Preto-USP (2010-2016) and School of Dentistry, University of Alabama at Birmingham (2014) Laser Therapy (2022), School of Dentistry-USP. Employment History: OMF surgeon, 1st lieutenant at Brazilian Navy (2006-2010). Professor, Department of Surgery, Prosthesis and Traumatology, Faculty of Dentistry -USP (2018-2022). Professor, Department of Oral and Maxillofacial Surgery and Traumatology and Periodontics at the Faculty of Dentistry of Ribeirão Preto - USP (2022- ) Research interests Regenerative bone therapies Anxiety and post operative pain (Source: Lattes Curriculum)
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In order to improve bone regeneration, the use of mesenchymal stem cells (MSC) from different sources have been widely explored. MSCs from adipose tissue (MSC-AT) are an attractive alternative since a higher number of cells are easily harvested at lesser morbidity compared to cells obtained from other sources. However, their use is limited due to their lower less osteogenic potential. To …
Cell-based therapy has been used as a promising strategy for bone regeneration purposes, an approach of interest in the filed of maxillofacial and orthopedics surgeries. Among the cell types, the mesenchymal stem cells derived from adipose tissue (AT-MSC) emerge as a good alternative once they are easily harvested with lower morbidity, compared to the cells obtained from bone marrow (BM-M…
Experimental models using rodents are critical to evaluating the efficacy of bone tissue regeneration therapies. Our research group have been investigating the effect of injection of mesenchymal stem cells (MSCs) on the repair of defects in rat calvaria, with interesting results, although regeneration has not yet been achieved. Therefore, it is necessary to investigate the molecular, cell…
Despite technological and scientific advances in bone regeneration, there is still no biomaterial with the ideal characteristics to replace large bone defects, and the association of biomaterials has been developed. The effects of bioactive glass (BG) incorporated with protein nanotubes (NT), in bone repair have been investigated; however, bone remodeling involves synergistic and controll…
To enhance the osteoblastic differentiation of mesenchymal stem cells (MSCs) derived from adipose tissue, photobiomodulation (FBM) emerges as a non-invasive therapy that has been related to the acceleration of the repair process. However, the mechanisms by which these effects occur have not been elucidated. We hypothesize that the medium conditioned by MSCs treated with PBM increases oste…
Bone defect treatments remain a challenge faced by professionals from different areas. Among the therapeutic strategies, the use of biomaterials associated or not with cells and/or growth factors Isa promising therapy. Up to now, no one material is suitable for use as a bone substitute, and the association of biomaterials has been investigated. In this context, our research group has been…
Bone tissue engineering is a therapeutic approach based on the combination of scaffolds, growth factors, and cells. Regarding the cells, adipose tissue-derived mesenchymal stem cells (AT-MSC) can be easily harvested at lesser morbidity. However, its use is limited due to its lower less osteogenic potential. In this context, strategies to increase the therapeutic potential of MSCs or "Cell…
Diabetes Mellitus (DM) is a chronic metabolic disease that impairs bone repair. DM is characterized by hyperglycemia that results in an increase in osteoclast activity associated with a decrease in osteoblast differentiation and activity, increasing the risk of bone fractures and impairing functional aesthetic rehabilitation of the bone defects. The mechanisms by which diabetes affects bo…
(Only some records are available in English at this moment)
Bone tissue engineering uses the combination of cells, biochemical factors and scaffolds to replace bone tissue and recover its biological functions. Among the biomaterials that have been employed as scaffolds, bioactive glasses emerge as a promising alternative, due to their ability to stimulate in vitro osteogenesis. This process may be regulated by post-transcriptional mechanisms invol…
| 1 / 1 | Ongoing research grants |
| 2 / 1 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 9 / 9 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 16 / 15 | All research grants and scholarships |
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CV Lattes
ORCID