Abstract
In the X-chromosome inactivation (XCI), one of the two X chromosomes present in female mammals is silenced, resulting in a dosage compensation mechanism. The XCI can occur in a random fashion, where each cell chooses randomly which is the inactivated X chromosome, paternal (Xp) or maternal (Xm); or dependent on parental origin of X chromosome, ie, imprinted. While in female marsupials, in…