Abstract
The acute kidney injury (AKI) is one of the major public health problems in the world. In South America, the incidence of AKI is 31%, while in Brazil AKI corresponds to 5% of total number of hospitalizations and 30% of Intensive Care Unit (ICU) admissions. One of the causes of AKI is the ischemia and reperfusion injury (IRI), which is induced by impairment in the delivery of oxygen and nu…