- Research Grants
graduate at Biomedicina from Universidade Estadual de Santa Cruz (2007). Has experience in Genetics, focusing on Genetics (Source: Lattes Curriculum)
TP53 is considered the most important tumor suppressor gene and acts as a potent transcription factor, playing a key role in maintaining genomic stability. The p53 protein consists of 393 amino acids and contains three structural domains, an N-terminal activation domain, a central DNA binding domain and a C-terminal oligomerization domain. A mutation in the p53 C-terminal domain is asso...
The human adult adrenal cortex is composed of the zona glomerulosa (zG), zona fasciculata (zF), and zona reticularis (zR), which are responsible for production of mineralocorticoids, glucocorticoids, and adrenal androgens, respectively. Starting shortly after birth, a rapid, dramatic remodeling of adrenal cortex structure takes place, with massive shrinkage of the gland due to apoptosis...
CDKN1C (p57KIP2) is a cyclin-dependent kinase inhibitor, member of the CIP/KIP family, which includes p21 and p27. CDKN1C and is located at the chromosomal locus 11p15. p57KIP2 presents higher expression levels during organogenesis, however its expression disappears after birth, except for adrenal cortex. In this case, its expression is maintained in the adult organ and its silencing is...
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
|Data from Web of Science|
(References retrieved automatically from State of São Paulo Research Institutions)
BORGES, Kleiton Silva. Mecanismos Envolvidos com a Inibição de Aurora-Quinases em Carcinoma de Adrenal. 2014. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (10/08699-5)