CV Lattes
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ORCID
Universidade Cruzeiro do Sul (UNICSUL). Centro de Ciências Biológicas e da Saúde (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Educação Física from Universidade Estadual de Maringá (2007), master's at Physiology from Universidade de São Paulo (2010) and doctorate at Physiology from Universidade de São Paulo (2014). Has experience in Physiology, focusing on Physiology, acting on the following subjects: diabetes, inflamação, hiperglicemia, epigenética and cell death. (Source: Lattes Curriculum)
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Hyperglycemia causes epigenetic changes associated with persistent activation of inflammatory pathways, a phenomenon known as 'metabolic memory'. Given the nature of the differentiation and the relatively short half-lives of leukocytes, particularly monocytes/macrophages in inflammation, memory of the innate immune system results from epigenetic imprint on bone marrow hematopoietic stem p…
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into chondrocytes, osteocytes, and adipocytes. Although they were originally identified and described as 'marrow stromal cells, they have been identified in many other anatomical sites in the body. MSCs can be isolated from bone marrow, adipose tissue, umbilical cord, and other tissues, but the most abundant ti…
Type 2 diabetes mellitus (T2DM) is one of the prevalent pathologies in modern civilization and has obesity as the main risk factor. However, the prevalence of T2DM has been increasing despite the low prevalence of obesity in some populations, including the Japanese subjects. With or without obesity, non-alcoholic fatty liver disease (NAFLD) is constantly associated with T2DM. NAFLD is cha…
MicroRNAs (miRNAs) are involved in the control of energy metabolism and development of chronic diseases, such as obesity, T2DM, and metabolic syndrome. The identification of miRNAs associated with T2DM development is essential to understand the syndrome etiology and direct futher therapeutic studies. This project aims to characterize the expression profile of circulating exosomal miRNAs i…
(Only some records are available in English at this moment)
Epigenetic modifications are one of the most important means for control of gene activity; in essence to store, retain, and recall past experiences in a way to shape present and future behaviour. Over the last decade we have characterised the key epigenetic changes imprinted following exposure to high glucose levels. In addition, we have shown that this epigenetic programming directly con…
| 2 / 2 | Completed research grants |
| 4 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 7 / 7 | All research grants and scholarships |
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