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Marciane Milanski Ferreira

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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

1993 1997 B.S. in Nutrition, Federal University of Mato Grosso, UFMT, Brazil; 1997 1998 Specialization in Public Health, University of Ribeirão Preto, UNAERP, Brazil; 2003 2005 M.S. in Health Sciences, Federal University of Mato Grosso, UFMT, Brazil; 2007 2008 Ph.D. in Biochemistry, University of Barcelona, Spain; 2005 2009 Ph.D. in Medical Clinic University of Campinas, UNICAMP, Brazil; 2009 2011 Postdoctoral Training in Medical Clinic University of Campinas, UNICAMP, Brazil; 2016 - 2017 Visiting Professor Cell Biology Program SickKids Research Institute/Toronto-CA; 2017 2017 Visiting Professor - Université PARIS- DIDEROT 7/França MAIN INTEREST IN RESEARCH - Role of lipid excess (saturated fat acids and interesterified lipids) in the development of obesity and type 2 diabetes. Metabolic and molecular aspects. Significant scientific contributions: - Characterization of the role of high-fat diets in body energy homeostasis and the mechanisms involved in hypothalamic resistance to leptin and insulin. - Identification of TLR4 activation and subsequent induction of endoplasmic reticulum stress as mechanisms involved in hypothalamic resistance to leptin and insulin. Central inhibition of inflammation in DIO animals, by blocking the activation of TLR4 or ER stress was able to reverse the glucose homeostasis in part by inhibition of hepatic glucose production. - Role of hypothalamic autophagy in the regulation of glucose homeostasis induced by obesity - Characterization of the role of interesterified fat in metabolism. Interesterified soybean oil promotes weight, impaired glucose tolerance and increase liver cellular stress markers in Swiss mice. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications5
Citations26
Cit./Article5.2
Data from Web of Science

PORTOVEDO, MARIANA; IGNACIO-SOUZA, LETICIA M.; BOMBASSARO, BRUNA; COOPE, ANDRESSA; REGINATO, ANDRESSA; RAZOLLI, DANIELA S.; TORSONI, MARCIO A.; TORSONI, ADRIANA S.; LEAL, RAQUEL F.; VELLOSO, LICIO A.; et al. Saturated Fatty Acids Modulate Autophagy's Proteins in the Hypothalamus. PLoS One, v. 10, n. 3, . Web of Science Citations: 23. (11/14565-4)

MIYAMOTO, JOSIANE ERICA; FERRAZ, ANA CAROLINA G.; PORTOVEDO, MARIANA; REGINATO, ANDRESSA; STAHL, MARCELLA APARECIDA; IGNACIO-SOUZA, LETICIA MARTINS; CHAN, KENNY L.; TORSONI, ADRIANA SOUZA; TORSONI, MARCIO ALBERTO; BADAN RIBEIRO, ANA PAULA; et al. Interesterified soybean oil promotes weight gain, impaired slucose tolerance and increased liver cellular stress markers. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, v. 59, p. 153-159, . Web of Science Citations: 1.

PORTOVEDO, M.; REGINATO, A.; MIYAMOTO, J. E.; SIMINO, L. A.; HAKIM, M. P.; CAMPANA, M.; LEAL, R. F.; IGNACIO-SOUZA, L. M.; TORSONI, M. A.; MAGNAN, C.; et al. Lipid excess affects chaperone-mediated autophagy in hypothalamus. Biochimie, v. 176, p. 110-116, . Web of Science Citations: 1. (14/11751-0, 13/10911-0)

MIYAMOTO, JOSIANE ERICA; REGINATO, ANDRESSA; PORTOVEDO, MARIANA; DOS SANTOS, RAISA MAGNO; STAHL, MARCELLA APARECIDA; LE STUNFF, HERVE; LATORRACA, MARCIA QUEIROZ; DE BARROS REIS, MARISE AUXILIADORA; ARANTES, VANESSA CRISTINA; DONEDA, DIEGO LUIZ; et al. Interesterified palm oil impairs glucose homeostasis and induces deleterious effects in liver of Swiss mice. METABOLISM-CLINICAL AND EXPERIMENTAL, v. 112, . Web of Science Citations: 1. (16/24768-3)

REGINATO, ANDRESSA; SIQUEIRA, BEATRIZ PIATEZZI; MIYAMOTO, JOSIANE ERICA; PORTOVEDO, MARIANA; COSTA, SULEYMA DE OLIVEIRA; DE FANTE, THAIS; RODRIGUES, HOSANA GOMES; IGNACIO-SOUZA, LETICIA MARTINS; TORSONI, MARCIO ALBERTO; TORSONI, ADRIANA SOUZA; et al. Acute effects of fatty acids on autophagy in NPY neurones. Journal of Neuroendocrinology, v. 32, n. 10, . Web of Science Citations: 0. (15/25710-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ARAÚJO, Mariana Portovedo de Oliveira. A regulação da autofagia mediada por chaperonas no hipotálamo em resposta ao excesso de lipídeos = Regulation of hypothalamic chaperone-mediated autophagy in response to lipid overload. Tese (Doutorado) -  Universidade Estadual de Campinas, Faculdade de Ciências Aplicadas.  (13/10911-0

ARAÚJO, Mariana Portovedo de Oliveira. Modulação da autofagia hipotalâmica em camundongos alimentados com dieta hiperlipídica. Dissertação (Mestrado) -  Faculdade de Ciências Aplicadas.  Universidade Estadual de Campinas (UNICAMP).  (11/14565-4

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