Abstract
The Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder manifested primarily in adults over the age of 50 years characterized by a progressive failure of motor neurons in the spinal cord. The etiology of the disease is not yet fully elucidated. However, it is postulated that 90-95% of cases are sporadic origin and 5-10 % of family origin. Among the familial cases, 20-25% o…