CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associated Professor at the University of Sao Paulo Medical School. Standing Member of the Editorial Board of WHO Classification of tumors (WHO/IARC - Blue books)(2022-2024);Member of the Board of the International Collaboration on Cancer Reporting (ICCR);Councilor for Latin America of International Society of Urological Pathology (ISUP) from 2015 to 2019.President of The Brazilian Society of Pathology (2020-202). Graduation in Medicine at Universidade de São Paulo (1984).PhD at Universidade Federal de São Paulo (2000). Has experience in Uropathology and Molecular Pathology. (Source: Lattes Curriculum)
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In a pilot study, we identified pathogenic variants of uncertain significance and missense variants in representative cases of Gleason pattern 5 and ductal histologic variant, many related to actionable pathways from a therapeutic standpoint. Our purpose for this project is to validate the molecular characterization of pattern 5 and ductal histological variant, which are known to behave m…
Prostate cancer is the most common cancer in men, and most patients have localized disease at the time of diagnosis. However, 4% already present with metastatic disease. Epithelial-mesenchymal transition is a fundamental process in carcinogenesis that has been shown to be involved in prostate cancer progression. The main event in epithelial-mesenchymal transition is the repression of E-ca…
Micro RNA (miRNA) are important regulators of gene expression and its changes are related to the development and progression of cancer. Studies of literature and previous results obtained by our laboratory imply some miRNA in progression and biochemical recurrence of prostate cancer. Are already available miRNA molecules to treat diseases. The purpose of this study is the research of the …
Kidney tumors with oncocytic features encompass widely known entities, such as oncocytomas and chromophobe carcinomas, as well as a variety of subtypes with mid-ground characteristics, formerly called "hybrid oncocytoma-chromophobe tumors". Recently, however, the publication of the 5th edition of the IARC/WHO book established new entities for the classification of this "intermediate zone"…
Prostate Cancer (PCa) is the most common neoplasm in men and the second leading cause of cancer mortality. Patients are diagnosed through biopsy and receive treatment according to the aggressive potential of the neoplasm, with radical prostatectomy and radiotherapy being the treatments considered curative. Among the various causes that contribute to tumorigenesis are mutations in the mism…
Despite the great advances in available treatments for prostate cancer, this condition remains a major health issue, with an alarming incidence and mortality. The increasing knowledge of its molecular characteristics opens allows the development of new therapies that target specific molecules related to the pathogenesis of this disease. The role of microRNAs - not coding small strands of …
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 17 / 2 | Completed research grants |
| 9 / 6 | Completed scholarships in Brazil |
| 27 / 9 | All research grants and scholarships |
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