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Eneida de Paula

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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Nurse bachelor at Universidade Estadual de Campinas, Unicamp (1985), master in Biochemistry at Unicamp (1988) and Ph.D in Biochemistry at Universidade de São Paulo (1993); Full professor in Biochemistry, Unicamp (2010). Has experience in Byophysics, Biochemistry and pharmacy, focusing on Membranes and Biomimetic systems, acting on the following subjects: local anesthetics, drug delivery, liposomes, nanostructure lipid carriers, membranes, spectroscopic methods. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
Novel formulation of an injectable drug to treat joint inflammation acts for up to ten days 
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FAPESP support in numbers * Updated February 22, 2020
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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (87)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications79
Citations825
Cit./Article10.4
Data from Web of Science

NASCIMENTO, M. H. M.; FRANCO, M. K. K. D.; YOKAICHYIA, F.; DE PAULA, E.; LOMBELLO, C. B.; DE ARAUJO, D. R.. Hyaluronic acid in Pluronic F-127/F-108 hydrogels for postoperative pain in arthroplasties: Influence on physico-chemical properties and structural requirements for sustained drug-release. International Journal of Biological Macromolecules, v. 111, p. 1245-1254, . Web of Science Citations: 11. (14/26200-9, 15/14763-1, 14/14457-5)

RENNO, CAROLINA C.; PAPINI, JULIANA Z. B.; SAIA CEREDA, CINTIA MARIA; MARTINEZ, ELIZABETH; MONTALLI, VICTOR ANGELO; DE PAULA, ENEIDA; PEDRAZZOLI JUNIOR, JOSE; CALAFATTI, SILVANA APARECIDA; TOFOLI, GIOVANA RADOMILLE. Preclinical Evaluation of Ropivacaine in 2 Liposomal Modified Systems. ANESTHESIA AND ANALGESIA, v. 129, n. 2, p. 387-396, . Web of Science Citations: 0. (14/14457-5)

GUILHERME, VIVIANE A.; RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; CASTRO, SIMONE R.; RODRIGUES DA SILVA, GUSTAVO H.; DA SILVA, CAMILA GONCALVES; BREITKREITZ, MARCIA C.; CLEMENTE-NAPIMOGA, JULIANA; MACEDO, CRISTINA G.; ABDALLA, HENRIQUE B.; et al. Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 0. (13/10766-0, 14/14457-5)

OLIVEIRA, JULIANA DAMASCENO; DE MORAIS RIBEIRO, LIGIA NUNES; RODRIGUES DA SILVA, GUSTAVO HENRIQUE; CASADEI, BRUNA RENATA; COUTO, VERONICA MUNIZ; MARTINEZ, ELIZABETH FERREIRA; DE PAULA, ENEIDA. Sustained Release from Ionic-Gradient Liposomes Significantly Decreases ETIDOCAINE Cytotoxicity. PHARMACEUTICAL RESEARCH, v. 35, n. 12, . Web of Science Citations: 2. (14/14457-5)

ALVES, DANILO ANTONINI; MACHADO, DAISY; MELO, ADRIANA; CARNEIRO PEREIRA, RAFAELLA FABIANA; SEVERINO, PATRICIA; DE HOLLANDA, LUCIANA MARIA; ARAUJO, DANIELE RIBEIRO; LANCELLOTTI, MARCELO. Preparation of Thermosensitive Gel for Controlled Release of Levofloxacin and Their Application in the Treatment of Multidrug-Resistant Bacteria. BIOMED RESEARCH INTERNATIONAL, . Web of Science Citations: 1. (11/21822-3, 11/21685-6, 14/14457-5)

RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; RODRIGUES DA SILVA, GUSTAVO H.; FRANZ-MONTAN, MICHELLE; NISTA, SILVIA V. G.; CASTRO, SIMONE R.; COUTO, VERONICA M.; GUILHERME, VIVIANE A.; DE PAULA, ENEIDA. Advances in Hybrid Polymer-Based Materials for Sustained Drug Release. INTERNATIONAL JOURNAL OF POLYMER SCIENCE, . Web of Science Citations: 4. (14/25372-0, 14/14457-5)

MARTINS, PAULA; MACHADO, DAISY; THEIZEN, THAIS HOLTZ; OLIVEIRA GUARNIERI, JOAO PAULO; BERNARDES, BRUNO GAIA; GOMIDE, GABRIEL PICCIRILLO; FINZI CORAT, MARCUS ALEXANDRE; ABBEHAUSEN, CAMILLA; PROENCA MODENA, JOSE LUIZ; ODIR RODRIGUES MELO, CARLOS FERNANDO; et al. Outer Membrane Vesicles from Neisseria Meningitidis (Proteossome) Used for Nanostructured Zika Virus Vaccine Production. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 4. (17/12719-0, 14/14457-5, 16/17066-2)

AKKARI, ALESSANDRA C. S.; BOAVA PAPINI, JULIANA Z.; GARCIA, GABRIELLA K.; DIAS FRANCO, MARGARETH K. K.; CAVALCANTI, LEIDE P.; GASPERINI, ANTONIO; ALKSCHBIRS, MELISSA INGER; YOKAICHYIA, FABIANO; DE PAULA, ENEIDA; TOFOLI, GIOVANA R.; et al. Poloxamer 407/188 binary thermosensitive hydrogels as delivery systems for infiltrative local anesthesia: Physico-chemical characterization and pharmacological evaluation. Materials Science & Engineering C-Materials for Biological Applications, v. 68, p. 299-307, . Web of Science Citations: 20. (14/26200-9, 14/14457-5)

FRANZ-MONTAN, MICHELLE; SERPE, LUCIANO; MAIA MARTINELLI, CLAUDIA CRISTINA; DA SILVA, CAMILA BATISTA; DOS SANTOS, CLEITON PITA; NOVAES, PEDRO DUARTE; VOLPATO, MARIA CRISTINA; DE PAULA, ENEIDA; VIANNA LOPEZ, RENATA FONSECA; GROPPO, FRANCISCO CARLOS. Evaluation of different pig oral mucosa sites as permeability barrier models for drug permeation studies. European Journal of Pharmaceutical Sciences, v. 81, p. 52-59, . Web of Science Citations: 8. (11/23475-9, 12/06974-4, 11/18113-0, 14/14457-5)

FRANZ-MONTAN, MICHELLE; DE MORAIS RIBEIRO, LIGIA NUNES; VOLPATO, MARIA CRISTINA; SAIA CEREDA, CINTIA MARIA; GROPPO, FRANCISCO CARLOS; TOFOLI, GIOVANA RANDOMILLE; DE ARAUJO, DANIELE RIBEIRO; SANTI, PATRIZIA; PADULA, CRISTINA; DE PAULA, ENEIDA. Recent advances and perspectives in topical oral anesthesia. Expert Opinion on Drug Delivery, v. 14, n. 5, p. 673-684, . Web of Science Citations: 13. (12/06974-4, 14/14457-5)

PRADO, ANDRESSA R.; YOKAICHIYA, FABIANO; KOBAYASHI DIAS FRANCO, MARGARETH KAZUYO; GONCALVES DA SILVA, CAMILA MORAIS; OLIVEIRA-NASCIMENTO, LAURA; FRANZ-MONTAN, MICHELLE; VOLPATO, MARIA C.; CABECA, LUIS F.; DE PAULA, ENEIDA. Complexation of oxethazaine with 2-hydroxypropyl--cyclodextrin: increased drug solubility, decreased cytotoxicity and analgesia at inflamed tissues. Journal of Pharmacy and Pharmacology, v. 69, n. 6, p. 652-662, . Web of Science Citations: 5. (14/14457-5)

GONCALVES DA SILVA, CAMILA MORAIS; FRACETO, LEONARDO FERNANDES; FRANZ-MONTAN, MICHELLE; COUTO, VERONICA MUNIZ; CASADEI, BRUNA RENATA; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA. Development of egg PC/cholesterol/alpha-tocopherol liposomes with ionic gradients to deliver ropivacaine. Journal of Liposome Research, v. 26, n. 1, p. 1-10, . Web of Science Citations: 10. (11/21735-3)

BRAGA, M. A.; MARTINI, M. F.; PICKHOLZ, M.; YOKAICHIYA, F.; FRANCO, M. K. D.; CABECA, L. F.; GUILHERME, V. A.; SILVA, C. M. G.; LIMIA, C. E. G.; DE PAULA, E.. Clonidine complexation with hydroxypropyl-beta-cyclodextrin: From physico-chemical characterization to in vivo adjuvant effect in local anesthesia. Journal of Pharmaceutical and Biomedical Analysis, v. 119, p. 27-36, . Web of Science Citations: 7. (06/00121-9)

RODRIGUES DA SILVA, GUSTAVO HENRIQUE; DE MORAIS RIBEIRO, LIGIA NUNES; GUILHERME, VIVIANE APARECIDA; DE CASTRO, SIMONE RAMOS; BREITKREITZ, MARCIA CRISTINA; DE PAULA, ENEIDA. Bupivacaine (S75:R25) Loaded in Nanostructured Lipid Carriers: Factorial Design, HPLC Quantification Method and Physicochemical Stability Study. CURRENT DRUG DELIVERY, v. 15, n. 3, p. 388-396, . Web of Science Citations: 0. (14/14457-5)

SAIA CEREDA, CINTIA MARIA; MECATTI, DANIEL SEBBE; BOAVA PAPINI, JULIANA ZAMPOLI; BUENO, DIEGO VALERIO; FRANZ-MONTAN, MICHELLE; ROCHA, THALITA; PEDRAZZOLI JUNIOR, JOSE; DE PAULA, ENEIDA; DE ARAUJO, DANIELE RIBEIRO; GRILLO, RENATO; et al. Bupivacaine in alginate and chitosan nanoparticles: an in vivo evaluation of efficacy, pharmacokinetics, and local toxicity. JOURNAL OF PAIN RESEARCH, v. 11, p. 683-691, . Web of Science Citations: 2. (14/14457-5)

RODRIGUES DA SILVA, GUSTAVO H.; RIBEIRO, LIGIA N. M.; MITSUTAKE, HERY; GUILHERME, VIVIANE A.; CASTRO, SIMONE R.; POPPI, RONEI J.; BREITKREITZ, MARCIA C.; DE PAULA, ENEIDA. Optimised NLC: a nanotechnological approach to improve the anaesthetic effect of bupivacaine. International Journal of Pharmaceutics, v. 529, n. 1-2, p. 253-263, . Web of Science Citations: 11. (14/14457-5)

BARBOSA, RAQUEL DE M.; RIBEIRO, LIGIA N. M.; CASADEI, BRUNA R.; DA SILVA, CAMILA M. G.; QUEIROZ, VIVIANE A.; DURAN, NELSON; DE ARAUJO, DANIELE R.; SEVERINO, PATRICIA; DE PAULA, ENEIDA. Solid Lipid Nanoparticles for Dibucaine Sustained Release. PHARMACEUTICS, v. 10, n. 4, . Web of Science Citations: 4. (14/14457-5)

NASCIMENTO VIEIRA, ANA LAIS; FRANZ-MONTAN, MICHELLE; CABECA, LUIS FERNANDO; DE PAULA, ENEIDA. Anaesthetic benefits of a ternary drug delivery system (Ropivacaine-in-Cyclodextrin-in-Liposomes): in-vitro and in-vivo evaluation. Journal of Pharmacy and Pharmacology, . Web of Science Citations: 0. (14/14457-5)

MUNIZ, BRUNO VILELA; BARATELLI, DIEGO; DI CARLA, STEPHANY; SERPE, LUCIANO; DA SILVA, CAMILA BATISTA; GUILHERME, VIVIANE APARECIDA; DE MORAIS RIBEIRO, LIGIA NUNES; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA; VOLPATO, MARIA CRISTINA; et al. Hybrid Hydrogel Composed of Polymeric Nanocapsules Co-Loading Lidocaine and Prilocaine for Topical Intraoral Anesthesia. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 2. (13/22326-5, 12/06974-4, 14/14457-5)

VIGATO, ARYANE ALVES; QUEROBINO, SAMYR MACHADO; DE FARIA, NAIALLY CARDOSO; PINHEIRO DE FREITAS, ANDREA CAROLINA; LEONARDI, GISLAINE RICCI; DE PAULA, ENEIDA; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; DE ARAUJO, DANIELE RIBEIRO. Synthesis and characterization of nanostructured lipid-poloxamer organogels for enhanced skin local anesthesia. European Journal of Pharmaceutical Sciences, v. 128, p. 270-278, . Web of Science Citations: 4. (14/14457-5, 18/02482-6, 18/04036-3)

SAIA CEREDA, CINTIA MARIA; GUILHERME, VIVIANE APARECIDA; ALKSCHBIRS, MELISSA INGER; DE BRITO JUNIOR, RUI BARBOSA; TOFOLI, GIOVANA RADOMILLE; FRANZ-MONTAN, MICHELLE; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. Journal of Liposome Research, v. 27, n. 1, p. 74-82, . Web of Science Citations: 1. (06/00121-9)

ORTEGA, VANESSA; GIORGIO, SELMA; DE PAULA, ENEIDA. Liposomal formulations in the pharmacological treatment of leishmaniasis: a review. Journal of Liposome Research, v. 27, n. 3, p. 234-248, . Web of Science Citations: 2. (13/01536-1, 14/12443-7)

GUILHERME, VIVIANE A.; RIBEIRO, LIGIA N. M.; TOFOLI, GIOVANA RADOMILLE; FRANZ-MONTAN, MICHELLE; DE PAULA, ENEIDA; DE JESUS, MARCELO BISPO. Current Challenges and Future of Lipid Nanoparticles Formulations for Topical Drug Application to Oral Mucosa, Skin, and Eye. CURRENT PHARMACEUTICAL DESIGN, v. 23, n. 43, p. 6659-6675, . Web of Science Citations: 5. (14/03002-7, 14/14457-5)

RIBEIRO, LIGIA N. M.; BREITKREITZ, MARCIA C.; GUILHERME, VIVIANE A.; DA SILVA, GUSTAVO H. R.; COUTO, VERONICA M.; CASTRO, SIMONE R.; DE PAULA, BARBARA O.; MACHADO, DAISY; DE PAULA, ENEIDA. Natural lipids-based NLC containing lidocaine: from pre-formulation to in vivo studies. European Journal of Pharmaceutical Sciences, v. 106, p. 102-112, . Web of Science Citations: 18. (14/25372-0, 14/14457-5)

RIBEIRO COSTA, JULIANA SOUZA; CRUVINEL, KAREN DE OLIVEIRA; OLIVEIRA-NASCIMENTO, LAURA. A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates. JOURNAL OF ADVANCED RESEARCH, v. 20, p. 33-41, . Web of Science Citations: 1. (17/06613-5, 14/14457-5)

CASADEI, BRUNA RENATA; CARVALHO, PATRICIA DE OLIVEIRA; RISKE, KARIN A.; BARBOSA, RAQUEL DE MELO; DE PAULA, ENEIDA; DOMINGUES, CLEYTON CREPALDI. Brij detergents reveal new aspects of membrane microdomain in erythrocytes. MOLECULAR MEMBRANE BIOLOGY, v. 31, n. 6, p. 195-205, . Web of Science Citations: 7. (09/00904-1, 10/18516-5)

DE JESUS, MARCELO BISPO; RADAIC, ALLAN; ZUHORN, INGE S.; DE PAULA, ENEIDA. Microemulsion extrusion technique: a new method to produce lipid nanoparticles. JOURNAL OF NANOPARTICLE RESEARCH, v. 15, n. 10, . Web of Science Citations: 7. (09/13110-3, 12/01038-9)

DE ARAUJO, DANIELE R.; DA SILVA, DEYSE C.; BARBOSA, RAQUEL M.; FRANZ-MONTAN, MICHELLE; CEREDA, CINTIA M. S.; PADULA, CRISTINA; SANTI, PATRIZIA; DE PAULA, ENEIDA. Strategies for delivering local anesthetics to the skin: focus on liposomes, solid lipid nanoparticles, hydrogels and patches. Expert Opinion on Drug Delivery, v. 10, n. 11, p. 1551-1563, . Web of Science Citations: 31. (10/11475-1, 06/00121-9, 11/05581-6)

SANTOS AKKARI, ALESSANDRA CRISTINA; RAMOS CAMPOS, ESTEFANIA VANGELIE; KEPPLER, ARTUR FRANZ; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA; TOFOLI, GIOVANA RADOMILLE; DE ARAUJO, DANIELE RIBEIRO. Budesonide-hydroxypropyl-beta-cyclodextrin inclusion complex in binary poloxamer 407/403 system for ulcerative colitis treatment: A physico-chemical study from micelles to hydrogels. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 138, p. 138-147, . Web of Science Citations: 12. (14/26200-9, 14/14457-5)

FRANZ-MONTAN, MICHELLE; BARONI, DANIELA; BRUNETTO, GIOVANA; VIEIRA SOBRAL, VIVIANE ROBERTA; GONCALVES DA SILVA, CAMILA MORAIS; VENANCIO, PAULO; ZAGO, PATRICIA WIZIACK; SAIA CEREDA, CINTIA MARIA; VOLPATO, MARIA CRISTINA; DE ARAUJO, DANIELE RIBEIRO; et al. Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans. Journal of Liposome Research, v. 25, n. 1, p. 11-19, . Web of Science Citations: 21. (06/00121-9, 09/08860-3, 07/05734-1)

DE ARAUJO, DANIELE RIBEIRO; PADULA, CRISTINA; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; BRITO, JR., RUI BARBOSA; DE PAULA, ENEIDA; NICOLI, SARA; SANTI, PATRIZIA. Bioadhesive Films Containing Benzocaine: Correlation Between In Vitro Permeation and In Vivo Local Anesthetic Effect. PHARMACEUTICAL RESEARCH, v. 27, n. 8, p. 1677-1686, . Web of Science Citations: 22. (06/00121-9)

GRILLO, RENATO; DE MELO, NATHALIE F. S.; DE ARAUJO, DANIELE R.; DE PAULA, ENEIDA; DIAS FILHO, NEWTON L.; ROSA, ANDRE H.; FRACETO, LEONARDO F.. Validation of an HPLC Method for quantitative Determination of Benzocaine in PHBV-Microparticles and PLA-Nanoparticles. Latin American Journal of Pharmacy, v. 28, n. 3, p. 393-399, . Web of Science Citations: 16. (08/01222-9, 06/00121-9)

GRILLO, RENATO; DE MELO, NATHALIE F. S.; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA; ROSA, ANDRE HENRIQUE; FRACETO, LEONARDO FERNANDES. Polymeric alginate nanoparticles containing the local anesthetic bupivacaine. Journal of Drug Targeting, v. 18, n. 9, p. 688-699, . Web of Science Citations: 44. (08/01222-9, 06/00121-9)

PRETÉ‚ PSC; MALHEIROS‚ SVP; MEIRELLES‚ NC; DE PAULA‚ E.. Quantitative assessment of human erythrocyte membrane solubilization by Triton X-100. Biophysical Chemistry, v. 97, n. 1, p. 1-5, .

PRETÉ‚ PSC; GOMES‚ K.; MALHEIROS‚ SVP; MEIRELLES‚ NC; DE PAULA‚ E.. Solubilization of human erythrocyte membranes by non-ionic surfactants of the polyoxyethylene alkyl ethers series. Biophysical Chemistry, v. 97, n. 1, p. 45-54, .

DE PAULA, ENEIDA; CEREDA, CINTIA M. S.; FRACETO, LEONARDO F.; DE ARAUJO, DANIELE R.; FRANZ-MONTAN, MICHELLE; TOFOLI, GIOVANA R.; RANALI, JOSE; VOLPATO, MARIA C.; GROPPO, FRANCISCO C.. Micro and nanosystems for delivering local anesthetics. Expert Opinion on Drug Delivery, v. 9, n. 12, p. 1505-1524, . Web of Science Citations: 48. (06/00121-9)

VOLOBUEF, CRISTIANE; MORAES, CAROLINA M.; NUNES, LAZARO A. S.; CEREDA, CINTIA M. S.; YOKAICHIYA, FABIANO; FRANCO, MARGARETH K. K. D.; BRAGA, ANGELICA F. A.; DE PAULA, ENEIDA; TOFOLI, GIOVANA RADOMILLE; FRACETO, LEONARDO F.; et al. Sufentanil-2-hydroxypropyl-beta-cyclodextrin inclusion complex for pain treatment: Physicochemical, cytotoxicity, and pharmacological evaluation. Journal of Pharmaceutical Sciences, v. 101, n. 10, p. 3698-3707, . Web of Science Citations: 6. (10/11475-1, 06/00121-9)

FRANCO DE LIMA, ROBERTA ALINE; DE JESUS, MARCELO BISPO; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; CABECA, LUIS FERNANDO; MAZZARO, IRINEU; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA. Improvement of tetracaine antinociceptive effect by inclusion in cyclodextrins. Journal of Drug Targeting, v. 20, n. 1, p. 85-96, . Web of Science Citations: 23. (06/03838-1)

TOFOLI, GIOVANA RADOMILLE; CEREDA, CINTIA M. S.; ARAUJO, DANIELE RIBEIRO; FRANZ-MONTAN, MICHELLE; GROPPO, FRANCISCO CARLOS; QUAGLIO, DAIANE; PEDRAZZOLI JUNIOR, JOSE; CALAFATTI, SILVANA APARECIDA; PROENCA BARROS, FABIO ALESSANDRO; DE PAULA, ENEIDA. Pharmacokinetic study of liposome-encapsulated and plain mepivacaine formulations injected intra-orally in volunteers. Journal of Pharmacy and Pharmacology, v. 64, n. 3, p. 397-403, . Web of Science Citations: 7. (06/00121-9)

FRANZ-MONTAN, M.; DE PAULA, E.; GROPPO, F. C.; SILVA, A. L. R.; RANALI, J.; VOLPATO, M. C.. Liposomal delivery system for topical anaesthesia of the palatal mucosa. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, v. 50, n. 1, p. 60-64, . Web of Science Citations: 19. (06/00121-9)

SILVA DE MELO, NATHALIE FERREIRA; GRILLO, RENATO; GUILHERME, VIVIANE APARECIDA; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA; ROSA, ANDRE HENRIQUE; FRACETO, LEONARDO FERNANDES. Poly(Lactide-co-Glycolide) Nanocapsules Containing Benzocaine: Influence of the Composition of the Oily Nucleus on Physico-Chemical Properties and Anesthetic Activity. PHARMACEUTICAL RESEARCH, v. 28, n. 8, p. 1984-1994, . Web of Science Citations: 29. (06/00121-9)

GONCALVES DA SILVA, CAMILA MORAIS; FRANZ-MONTAN, MICHELLE; GOMEZ LIMIA, CINTIA ELISABETH; DE MORAIS RIBEIRO, LIGIA NUNES; BRAGA, MARIO ANTONIO; GUILHERME, VIVIANE APARECIDA; DA SILVA, CAMILA BATISTA; CASADEI, BRUNA RENATA; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA. Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. PLoS One, v. 12, n. 10, . Web of Science Citations: 9. (14/14457-5, 11/21735-3)

DE MORAIS RIBEIRO, LIGIA NUNES; COUTO, VERONICA MUNIZ; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA. Use of nanoparticle concentration as a tool to understand the structural properties of colloids. SCIENTIFIC REPORTS, v. 8, . Web of Science Citations: 16. (14/25372-0, 14/14457-5)

NASCIMENTO, M. H. M.; FRANCO, M. K. K. D.; YOKAICHYIA, F.; DE PAULA, E.; LOMBELLO, C. B.; DE ARAUJO, D. R.. Hyaluronic acid in Pluronic F-127/F-108 hydrogels for postoperative pain in arthroplasties: Influence on physico-chemical properties and structural requirements for sustained drug-release. International Journal of Biological Macromolecules, v. 111, p. 1245-1254, . Web of Science Citations: 11. (14/26200-9, 15/14763-1, 14/14457-5)

RENNO, CAROLINA C.; PAPINI, JULIANA Z. B.; SAIA CEREDA, CINTIA MARIA; MARTINEZ, ELIZABETH; MONTALLI, VICTOR ANGELO; DE PAULA, ENEIDA; PEDRAZZOLI JUNIOR, JOSE; CALAFATTI, SILVANA APARECIDA; TOFOLI, GIOVANA RADOMILLE. Preclinical Evaluation of Ropivacaine in 2 Liposomal Modified Systems. ANESTHESIA AND ANALGESIA, v. 129, n. 2, p. 387-396, . Web of Science Citations: 0. (14/14457-5)

GUILHERME, VIVIANE A.; RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; CASTRO, SIMONE R.; RODRIGUES DA SILVA, GUSTAVO H.; DA SILVA, CAMILA GONCALVES; BREITKREITZ, MARCIA C.; CLEMENTE-NAPIMOGA, JULIANA; MACEDO, CRISTINA G.; ABDALLA, HENRIQUE B.; et al. Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 0. (13/10766-0, 14/14457-5)

OLIVEIRA, JULIANA DAMASCENO; DE MORAIS RIBEIRO, LIGIA NUNES; RODRIGUES DA SILVA, GUSTAVO HENRIQUE; CASADEI, BRUNA RENATA; COUTO, VERONICA MUNIZ; MARTINEZ, ELIZABETH FERREIRA; DE PAULA, ENEIDA. Sustained Release from Ionic-Gradient Liposomes Significantly Decreases ETIDOCAINE Cytotoxicity. PHARMACEUTICAL RESEARCH, v. 35, n. 12, . Web of Science Citations: 2. (14/14457-5)

ALVES, DANILO ANTONINI; MACHADO, DAISY; MELO, ADRIANA; CARNEIRO PEREIRA, RAFAELLA FABIANA; SEVERINO, PATRICIA; DE HOLLANDA, LUCIANA MARIA; ARAUJO, DANIELE RIBEIRO; LANCELLOTTI, MARCELO. Preparation of Thermosensitive Gel for Controlled Release of Levofloxacin and Their Application in the Treatment of Multidrug-Resistant Bacteria. BIOMED RESEARCH INTERNATIONAL, . Web of Science Citations: 1. (11/21822-3, 11/21685-6, 14/14457-5)

RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; RODRIGUES DA SILVA, GUSTAVO H.; FRANZ-MONTAN, MICHELLE; NISTA, SILVIA V. G.; CASTRO, SIMONE R.; COUTO, VERONICA M.; GUILHERME, VIVIANE A.; DE PAULA, ENEIDA. Advances in Hybrid Polymer-Based Materials for Sustained Drug Release. INTERNATIONAL JOURNAL OF POLYMER SCIENCE, . Web of Science Citations: 4. (14/25372-0, 14/14457-5)

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BARBOSA, RAQUEL DE M.; KLASSEN, ALINE; MARCATO, PRISCYLA D.; FRANZ-MONTAN, MICHELLE; GRILLO, RENATO; FRACETO, LEONARDO F.; DE PAULA, ENEIDA. Validation of an HPLC Method for the Determination of Dibucaine Encapsulated in Solid Lipid Nanoparticles and Nanostructured Lipid Carriers. Latin American Journal of Pharmacy, v. 32, n. 9, p. 1362-1369, . Web of Science Citations: 6. (06/00121-9)

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CARUSO, BENJAMIN; SANCHEZ, JULIETA M.; GARCIA, DANIEL A.; DE PAULA, ENEIDA; PERILLO, MARIA A.. Probing the Combined Effect of Flunitrazepam and Lidocaine on the Stability and Organization of Bilayer Lipid Membranes. A Differential Scanning Calorimetry and Dynamic Light Scattering Study. Cell Biochemistry and Biophysics, v. 66, n. 3, p. 461-475, . Web of Science Citations: 2. (06/00121-9)

RAMOS CAMPOS, ESTEFANIA VANGELIE; SILVA DE MELO, NATHALIE FERREIRA; GUILHERME, VIVIANE APARECIDA; DE PAULA, ENEIDA; ROSA, ANDRE HENRIQUE; DE ARAUJO, DANIELE RIBEIRO; FRACETO, LEONARDO FERNANDES. Preparation and characterization of poly(e-caprolactone) nanospheres containing the local anesthetic lidocaine. Journal of Pharmaceutical Sciences, v. 102, n. 1, p. 215-226, . Web of Science Citations: 24. (06/00121-9)

SAIA CEREDA, CINTIA MARIA; FRANZ-MONTAN, MICHELLE; GONCALVES DA SILVA, CAMILA MORAIS; CASADEI, BRUNA RENATA; DOMINGUES, CLEYTON CREPALDI; TOFOLI, GIOVANA RADOMILLE; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA. Transdermal delivery of butamben using elastic and conventional liposomes. Journal of Liposome Research, v. 23, n. 3, p. 228-234, . Web of Science Citations: 17. (06/00121-9)

FRANZ-MONTAN, MICHELLE; BARONI, DANIELA; BRUNETTO, GIOVANA; VIEIRA SOBRAL, VIVIANE ROBERTA; GONCALVES DA SILVA, CAMILA MORAIS; VENANCIO, PAULO; ZAGO, PATRICIA WIZIACK; SAIA CEREDA, CINTIA MARIA; VOLPATO, MARIA CRISTINA; DE ARAUJO, DANIELE RIBEIRO; et al. Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans. Journal of Liposome Research, v. 25, n. 1, p. 11-19, . Web of Science Citations: 21. (06/00121-9, 09/08860-3, 07/05734-1)

BARBOSA, RAQUEL M.; CASADEI, BRUNA R.; DUARTE, EVANDRO L.; SEVERINO, PATRICIA; BARBOSA, LEANDRO R. S.; DURAN, NELSON; DE PAULA, ENEIDA. Electron Paramagnetic Resonance and Small-Angle X-ray Scattering Characterization of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Dibucaine Encapsulation. Langmuir, v. 34, n. 44, p. 13296-13304, . Web of Science Citations: 7. (14/14457-5)

SCRIBONI, ANDREIA BORGES; COUTO, VERONICA MUNIZ; DE MORAIS RIBEIRO, LIGIA NUNES; FREIRES, IRLAN ALMEIDA; GROPPO, FRANCISCO CARLOS; DE PAULA, ENEIDA; FRANZ-MONTAN, MICHELLE; COGO-MULLER, KARINA. Fusogenic Liposomes Increase the Antimicrobial Activity of Vancomycin Against Staphylococcus aureus Biofilm. FRONTIERS IN PHARMACOLOGY, v. 10, . Web of Science Citations: 0. (14/14457-5)

GRILLO, RENATO; DIAS, V, FABIANA; QUEROBINO, SAMYR M.; ALBERTO-SILVA, CARLOS; FRACETO, LEONARDO F.; DE PAULA, ENEIDA; DE ARAUJOL, DANIELE R.. Influence of hybrid polymeric nanoparticle/thermosensitive hydrogels systems on formulation tracking and in vitro artificial membrane permeation: A promising system for skin drug-delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 174, p. 56-62, . Web of Science Citations: 5. (15/26189-8, 14/14457-5)

ALBANO, JUAN M. R.; DE MORAIS RIBEIRO, LIGIA NUNES; COUTO, VERONICA MUNIZ; MESSIAS, MARIANA BARBOSA; RODRIGUES DA SILVA, GUSTAVO HENRIQUE; BREITKREITZ, MARCIA CRISTINA; DE PAULA, ENEIDA; PICKHOLZ, MONICA. Rational design of polymer-lipid nanoparticles for docetaxel delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 175, p. 56-64, . Web of Science Citations: 4. (14/25372-0, 14/14457-5)

PEDREIRA DE ALMEIDA, ANA CLAUDIA; ALVES PINTO, LUCIANA MATOS; ALVES, GIULIANA PIOVESAN; DE MORAIS RIBEIRO, LIGIA NUNES; ANDRADE SANTANA, MARIA HELENA; SAIA CEREDA, CINTIA MARIA; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA. Liposomal-based lidocaine formulation for the improvement of infiltrative buccal anaesthesia. Journal of Liposome Research, v. 29, n. 1, p. 66-72, . Web of Science Citations: 0. (14/14457-5)

COUTO, VERONICA M.; PRIETO, MARIA J.; IGARTUA, DANIELA E.; FEAS, DANIELA A.; RIBEIRO, LIGIA N. M.; SILVA, CAMILA M. G.; CASTRO, SIMONE R.; GUILHERME, VIVIANE A.; DANTZGER, DARLENE D.; MACHADO, DAISY; et al. Dibucaine in Ionic-Gradient Liposomes: Biophysical, Toxicological, and Activity Characterization. Journal of Pharmaceutical Sciences, v. 107, n. 9, p. 2411-2419, . Web of Science Citations: 3. (13/13965-4, 14/14457-5)

DE MORAIS RIBEIRO, LIGIA NUNES; FRANZ-MONTAN, MICHELLE; BREITKREITZ, MARCIA CRISTINA; RODRIGUES DA SILVA, GUSTAVO HENRIQUE; DE CASTRO, SIMONE RAMOS; GUILHERME, VIVIANE APARECIDA; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA. Nanohybrid hydrogels designed for transbuccal anesthesia. INTERNATIONAL JOURNAL OF NANOMEDICINE, v. 13, p. 6453-6463, . Web of Science Citations: 3. (14/25372-0, 14/14457-5)

SILVA DE MELO, NATHALIE FERREIRA; RAMOS CAMPOS, ESTEFANIA VANGELIE; FRANZ-MONTAN, MICHELLE; DE PAULA, ENEIDA; GONCALVES DA SILVA, CAMILA MORAIS; MARUYAMA, CINTIA RODRIGUES; STIGLIANI, TATIANE PASQUOTO; DE LIMA, RENATA; DE ARAUJO, DANIELE RIBEIRO; FRACETO, LEONARDO FERNANDES. Characterization of Articaine-Loaded Poly(epsilon-caprolactone) Nanocapsules and Solid Lipid Nanoparticles in Hydrogels for Topical Formulations. Journal of Nanoscience and Nanotechnology, v. 18, n. 6, p. 4428-4438, . Web of Science Citations: 9. (10/18529-0)

GONCALVES DA SILVA, CAMILA MORAIS; FRANZ-MONTAN, MICHELLE; GOMEZ LIMIA, CINTIA ELISABETH; DE MORAIS RIBEIRO, LIGIA NUNES; BRAGA, MARIO ANTONIO; GUILHERME, VIVIANE APARECIDA; DA SILVA, CAMILA BATISTA; CASADEI, BRUNA RENATA; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA. Encapsulation of ropivacaine in a combined (donor-acceptor, ionic-gradient) liposomal system promotes extended anesthesia time. PLoS One, v. 12, n. 10, . Web of Science Citations: 9. (14/14457-5, 11/21735-3)

TOFOLI, GIOVANA R.; CEREDA, CINTIA M. S.; GROPPO, FRANCISCO C.; VOLPATO, MARIA C.; FRANZ-MONTAN, MICHELLE; RANALI, JOSE; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA. Efficacy of liposome-encapsulated mepivacaine for infiltrative anesthesia in volunteers. Journal of Liposome Research, v. 21, n. 1, p. 88-94, . Web of Science Citations: 16. (06/00121-9)

PICKHOLZ, MONICA; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA. Preferential location of prilocaine and etidocaine in phospholipid bilayers: A molecular dynamics study. Synthetic Metals, v. 159, n. 21-22, SI, p. 2157-2158, . Web of Science Citations: 4. (06/00121-9, 06/02523-7)

FERNANDES, SERGIO ANTONIO; CABEÇA, LUIZ FERNANDO; MARSAIOLI, ANITA JOCELYNE; PAULA, ENEIDA DE. Investigation of tetracaine complexation with beta-cyclodextrins and p-sulphonic acid calix[6]arenes by nOe and PGSE NMR. Journal of Inclusion Phenomena and Macrocyclic Chemistry, v. 57, n. 1/4, p. 395-401, . (05/00602-4)

DE JESUS, MARCELO BISPO; ALVES PINTO, LUCIANA DE MATOS; FRACETO, LEONARDO FERNANDES; MAGALHAES, LUIZ AUGUSTO; ZANOTTI-MAGALHAES, ELIANA MARIA; DE PAULA, ENEIDA. Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation. Journal of Drug Targeting, v. 18, n. 1, p. 21-26, . Web of Science Citations: 6. (06/03838-1)

RADAIC, ALLAN; DE PAULA, ENEIDA; DE JESUS, MARCELO BISPO. Factorial Design and Development of Solid Lipid Nanoparticles (SLN) for Gene Delivery. Journal of Nanoscience and Nanotechnology, v. 15, n. 2, p. 1793-1800, . Web of Science Citations: 10. (09/13110-3, 12/01038-9)

RODRIGUES DA SILVA, GUSTAVO HENRIQUE; DE MORAIS RIBEIRO, LIGIA NUNES; GUILHERME, VIVIANE APARECIDA; DE CASTRO, SIMONE RAMOS; BREITKREITZ, MARCIA CRISTINA; DE PAULA, ENEIDA. Bupivacaine (S75:R25) Loaded in Nanostructured Lipid Carriers: Factorial Design, HPLC Quantification Method and Physicochemical Stability Study. CURRENT DRUG DELIVERY, v. 15, n. 3, p. 388-396, . Web of Science Citations: 0. (14/14457-5)

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Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

FRACETO, Leonardo Fernandes. Anestésicos locais: interação com membranas e fragmento do canal de sódio voltagem dependente. 2003. 120f. Tese (Doutorado) – Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). Campinas.

PAULA, Eneida de. Preparo e caracterização de carreadores lipídicos nanoestruturados para bupivacaína em excesso enantiomérico (S75:R25) : Development and characterization of nanostructured lipid carriers for enantiomeric excess (S75:R25) of bupivacaine. 2017. Dissertação (Mestrado) -

FRACETO, Leonardo Fernandes. Localização de anestesicos locais do tipo amino-amida em lipossomas uni e multilamelares. 2000. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas.

PINTO, Luciana de Matos Alves. Interação dos anestesicos locais benzocaina, lidocaina e tetracaina com membranas modelo. 1998. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas.

GAONA, Vicky Vanessa Ortega. Desenvolvimento de um sistema de liberação sustentada de antimoniato de meglumina em lipossomas e avaliação de sua atividade em macrófagos DH82 infectados com "Leishmania infantum". 2016. Dissertação (Mestrado) -

RADAIC, Allan. Desenvolvimento de nanopartículas lipídicas para o carreamento conjunto do gene para PTEN e mitoxantrona em células de câncer de mama e de próstata. 2012. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).

JESUS, Marcelo Bispo de. Utilização de ferramentas nanotecnologicas para a indução de morte em celulas de cancer de prostata. 2009. Tese (Doutorado) – Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).

ARAUJO, Daniele Ribeiro de. Desenvolvimento e avaliação farmacologica de formulações de liberação controlada com anestesicos locais amino-amidas ciclicos : bupivacaina, mepivacaina e ropivacaina. 2005. Tese (Doutorado) – Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).

DAMASIO, Viviane Aparecida Guilherme. Naproxeno encapsulado em carreadores lipídicos nanoestruturados para administração parenteral = do preparo aos testes farmacológicos = Naproxen encapsulated in nanostructureted lipid carries for parenteral administration : from preparation to pharmacological tests. 2017. Dissertação (Mestrado) - Universidade Estadual de Campinas, Instituto de Biologia.

COUTO, Verônica Muniz. Encapsulação da dibucaína em lipossomas com gradiente iônico transmembranar. 2015. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).

GAONA, Vicky Vanessa Ortega. Desenvolvimento de um sistema de liberação sustentada de antimoniato de meglumina em lipossomas e avaliação de sua atividade em macrófagos DH82 infectados com "Leishmania infantum". 2016. Dissertação (Mestrado) -

RADAIC, Allan. Desenvolvimento de nanopartículas lipídicas para o carreamento conjunto do gene para PTEN e mitoxantrona em células de câncer de mama e de próstata. 2012. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP).

Patent applications

MÉTODO POR EXTRUSÃO DE MICROEMULSÃO À QUENTE PARA OBTENÇÃO DE NANOPARTICULAS LIPÍDICAS SÓLIDAS E CARREADORES LIPÍDICOS NANOESTRUTURADOS ASSIM OBTIDOS E USOS BR1020120273306 - Universidade Estadual de Campinas (UNICAMP). Eneida de Paula; Marcelo Bispo de Jesus; Allan Radaic - October 2012, 25

PROCESSO DE PRODUÇÃO DE NANOPARTÍCULAS DE QUITOSANA-TRIPOLIFOSFATO DISPERSAS EM HIDROGÉIS TERMORREVERSÍVEIS PARA LIBERAÇÃO INTRA-ARTICULAR DE FÁRMACOS, PRODUTO OBTIDO E APLICAÇÃO BR1020160181801 - Universidade Estadual de Campinas (UNICAMP); Universidade Estadual Paulista (UNESP); Universidade Federal do ABC (UFABC). Daniele Ribeiro De Araújo; Kelli Cristina Freitas Mariano; Leonardo Fernandes Fraceto; ; Estefânia Vangelie Ramos Campos; Jhones Luiz De Oliveira; Eneida De Paula - August 2016, 05

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COMPOSTO DE INCLUSÃO ENTRE B-CICLODEXTRINA E PRAZIQUANTEL PARA TRATAMENTO DE ESQUISTOSSOMOSE PI0401621-1 - Universidade Estadual de Campinas (UNICAMP). Leonardo Fernandes Fraceto; Luciana de Matos Alves Pinto; Eneida de Paula; Antonio Carlos Senges Lino; Marcelo Bispo de Jesus; Yuji Takahata - April 2004, 20

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