Eneida de Paula
CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Nurse bachelor at Universidade Estadual de Campinas, Unicamp (1985), master in Biochemistry at Unicamp (1988) and Ph.D in Biochemistry at Universidade de São Paulo (1993); Full professor in Biochemistry, Unicamp (2010). Has experience in Byophysics, Biochemistry and pharmacy, focusing on Membranes and Biomimetic systems, acting on the following subjects: local anesthetics, drug delivery, liposomes, nanostructure lipid carriers, membranes, spectroscopic methods. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Novel formulation of an injectable drug to treat joint inflammation acts for up to ten days |
- Development of controlled topical release formulations of the antimicrobian ciprofloxacin in ordered mesoporous silica and clays, AP.R
Abstract
The aim of this project is to facilitate the cooperation of 3 different research groups, from UNICAMP, USP and University of Copenhagen, in the quest of developing new antimicrobials, nanoformulated (with different drug-delivery carriers) and encapsulated in mesoporous silica/clays, to generate novel pharmaceutical formulations of increased antimicrobial activity against resistant patho...
- Multiuser equipment approved in grant # 2014/14457-5: PILOT shelf freeze-dryer, AP.EMU
Abstract
The pilot freeze dryer is essential to the development of lyophilized parenteral formulations that are reproducible, traceable, scalable, without contaminants and stable. Currently there is no pilot freeze dryer available for drug development in Unicamp. The main focus of our research group for years is the parenteral drug formulation, aimed not only at academic research but also the pr...
- Multiuser equipment approved in grant # 2014/14457-5: particle tracking analyzer and zeta POTENTIAL/DYNAMIC light scattering, AP.EMU
Abstract
The NanoSight NS300 Nanoparticle Tracking Analyzer and the Zeta sizer Nano ZS90 Dynamic Light Scatter are equipments based in complementary techniques, both being essential in the characterization of micro and nanoparticule systems such as the lipid-based drug-delivery systems for local anesthetics. The parenteral administration of those requires controlled sizes (< 500nm), low polydis...
(Only some records are available in English at this moment)
- Lipid-based nanocarriers for the local anesthetic tetracaine, BP.PD
Abstract
The encapsulation of Local Anesthetics (LA) in ionic gradient liposomes (IGL) has been shown to increase the time of analgesia and decrease the side effects, by maintaining the drug in the site of action for a longer time. Intradermal administration of IGL prepared with (NH4)2SO4 in a human volunteer achieved up to 19, 38, and 48 h of successful anesthesia with 0.5, 1, and 2% bupivacain...
- Citotoxicity and in vivo anesthesia effect of functional nanostructured lipid carriers loaded with S75:R25 bupivacaine, designed for burn treatment, BP.IC
Abstract
Pain control in burn injuries and their treatment remains a difficult challenge. Opioid therapy, although often used, has several limitations. An alternative to meet such demand is the application of local anesthetics, which are potential drugs for the treatment of such injuries. Bupivacaine is the local anesthetic most used worldwide in surgeries and postoperative periods, with a time ...
- Development of functional lipid nanoparticles for the improvement of the anesthetic potency at inflamed tissues, BP.DR
Abstract
Local Anesthetics (LA) are drugs widely used in medical and dental clinics capable of reversibly blocking the painful stimulus without loss of consciousness. However, in some cases AL may not have the desired effects, such as in inflamed tissues. In dental anesthesia, anesthetic failure or a lower degree of analgesia may occur in places with pulpitis or periodontitis processes installed...
(Only some records are available in English at this moment)
- Metabolomics of nanoparticles lipid carriers loaded with local anesthetic in vitro, BE.EP.DR
Abstract
Local anesthetics (AL) are drugs widely used in medical and dental clinics being capable of reversibly blocking the painful stimulus without loss of consciousness. However, in some cases AL may not have the desired effects, such as in inflamed tissues. To circumvent this situation, ALs can be encapsulated in nanostructured lipid carriers (NLC) composed of synthetic or natural excipients...
- Capsaicin in a local ANESTHETIC-BASED ionic liquid to selectively increase the anesthetic potency, BE.EP.DR
Abstract
Local anesthetics (LAs) are often used in medical practice when it is necessary to numb parts of the body. Although desirable, local anesthetics cannot guarantee the selective blockage of nociceptive fibers causing adverse reaction (motor and autonomic blockage). Recently, it was reported that the application of local anesthetic followed by capsaicin leads to a selective increase in sen...
- Role of hypercholesterolemia in modifying the composition of lipid rafts microdomains in prostate cancer, BE.EP.PD
Abstract
Lipid rafts are functional microdomains enriched in cholesterol and sphingolipids which are present in biological membranes. Operationally rafts are defined as detergent-resistant membranes (DRMs) since they resist to extraction by certain cold detergents. In the last decade, rafts have been described as potentially important organizers of survival signaling in prostate cancer cells, wi...
| 16 / 12 | Completed research grants |
| 44 / 20 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 63 / 35 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 79 |
| Citations | 825 |
| Cit./Article | 10.4 |
| Data from Web of Science | |
NASCIMENTO, M. H. M.; FRANCO, M. K. K. D.; YOKAICHYIA, F.; DE PAULA, E.; LOMBELLO, C. B.; DE ARAUJO, D. R.. Hyaluronic acid in Pluronic F-127/F-108 hydrogels for postoperative pain in arthroplasties: Influence on physico-chemical properties and structural requirements for sustained drug-release. International Journal of Biological Macromolecules, v. 111, p. 1245-1254, MAY 2018. Web of Science Citations: 11. (14/26200-9, 15/14763-1, 14/14457-5)
RENNO, CAROLINA C.; PAPINI, JULIANA Z. B.; SAIA CEREDA, CINTIA MARIA; MARTINEZ, ELIZABETH; MONTALLI, VICTOR ANGELO; DE PAULA, ENEIDA; PEDRAZZOLI JUNIOR, JOSE; CALAFATTI, SILVANA APARECIDA; TOFOLI, GIOVANA RADOMILLE. Preclinical Evaluation of Ropivacaine in 2 Liposomal Modified Systems. ANESTHESIA AND ANALGESIA, v. 129, n. 2, p. 387-396, AUG 2019. Web of Science Citations: 0. (14/14457-5)
GUILHERME, VIVIANE A.; RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; CASTRO, SIMONE R.; RODRIGUES DA SILVA, GUSTAVO H.; DA SILVA, CAMILA GONCALVES; BREITKREITZ, MARCIA C.; CLEMENTE-NAPIMOGA, JULIANA; MACEDO, CRISTINA G.; ABDALLA, HENRIQUE B.; et al. Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration. SCIENTIFIC REPORTS, v. 9, AUG 1 2019. Web of Science Citations: 0. (13/10766-0, 14/14457-5)
OLIVEIRA, JULIANA DAMASCENO; DE MORAIS RIBEIRO, LIGIA NUNES; RODRIGUES DA SILVA, GUSTAVO HENRIQUE; CASADEI, BRUNA RENATA; COUTO, VERONICA MUNIZ; MARTINEZ, ELIZABETH FERREIRA; DE PAULA, ENEIDA. Sustained Release from Ionic-Gradient Liposomes Significantly Decreases ETIDOCAINE Cytotoxicity. PHARMACEUTICAL RESEARCH, v. 35, n. 12, DEC 2018. Web of Science Citations: 2. (14/14457-5)
ALVES, DANILO ANTONINI; MACHADO, DAISY; MELO, ADRIANA; CARNEIRO PEREIRA, RAFAELLA FABIANA; SEVERINO, PATRICIA; DE HOLLANDA, LUCIANA MARIA; ARAUJO, DANIELE RIBEIRO; LANCELLOTTI, MARCELO. Preparation of Thermosensitive Gel for Controlled Release of Levofloxacin and Their Application in the Treatment of Multidrug-Resistant Bacteria. BIOMED RESEARCH INTERNATIONAL, 2016. Web of Science Citations: 1. (11/21822-3, 11/21685-6, 14/14457-5)
RIBEIRO, LIGIA N. M.; ALCANTARA, ANA C. S.; RODRIGUES DA SILVA, GUSTAVO H.; FRANZ-MONTAN, MICHELLE; NISTA, SILVIA V. G.; CASTRO, SIMONE R.; COUTO, VERONICA M.; GUILHERME, VIVIANE A.; DE PAULA, ENEIDA. Advances in Hybrid Polymer-Based Materials for Sustained Drug Release. INTERNATIONAL JOURNAL OF POLYMER SCIENCE, 2017. Web of Science Citations: 4. (14/25372-0, 14/14457-5)
MARTINS, PAULA; MACHADO, DAISY; THEIZEN, THAIS HOLTZ; OLIVEIRA GUARNIERI, JOAO PAULO; BERNARDES, BRUNO GAIA; GOMIDE, GABRIEL PICCIRILLO; FINZI CORAT, MARCUS ALEXANDRE; ABBEHAUSEN, CAMILLA; PROENCA MODENA, JOSE LUIZ; ODIR RODRIGUES MELO, CARLOS FERNANDO; et al. Outer Membrane Vesicles from Neisseria Meningitidis (Proteossome) Used for Nanostructured Zika Virus Vaccine Production. SCIENTIFIC REPORTS, v. 8, MAY 29 2018. Web of Science Citations: 4. (17/12719-0, 14/14457-5, 16/17066-2)
AKKARI, ALESSANDRA C. S.; BOAVA PAPINI, JULIANA Z.; GARCIA, GABRIELLA K.; DIAS FRANCO, MARGARETH K. K.; CAVALCANTI, LEIDE P.; GASPERINI, ANTONIO; ALKSCHBIRS, MELISSA INGER; YOKAICHYIA, FABIANO; DE PAULA, ENEIDA; TOFOLI, GIOVANA R.; et al. Poloxamer 407/188 binary thermosensitive hydrogels as delivery systems for infiltrative local anesthesia: Physico-chemical characterization and pharmacological evaluation. Materials Science & Engineering C-Materials for Biological Applications, v. 68, p. 299-307, NOV 1 2016. Web of Science Citations: 20. (14/26200-9, 14/14457-5)
FRANZ-MONTAN, MICHELLE; SERPE, LUCIANO; MAIA MARTINELLI, CLAUDIA CRISTINA; DA SILVA, CAMILA BATISTA; DOS SANTOS, CLEITON PITA; NOVAES, PEDRO DUARTE; VOLPATO, MARIA CRISTINA; DE PAULA, ENEIDA; VIANNA LOPEZ, RENATA FONSECA; GROPPO, FRANCISCO CARLOS. Evaluation of different pig oral mucosa sites as permeability barrier models for drug permeation studies. European Journal of Pharmaceutical Sciences, v. 81, p. 52-59, JAN 1 2016. Web of Science Citations: 8. (11/23475-9, 12/06974-4, 11/18113-0, 14/14457-5)
FRANZ-MONTAN, MICHELLE; DE MORAIS RIBEIRO, LIGIA NUNES; VOLPATO, MARIA CRISTINA; SAIA CEREDA, CINTIA MARIA; GROPPO, FRANCISCO CARLOS; TOFOLI, GIOVANA RANDOMILLE; DE ARAUJO, DANIELE RIBEIRO; SANTI, PATRIZIA; PADULA, CRISTINA; DE PAULA, ENEIDA. Recent advances and perspectives in topical oral anesthesia. Expert Opinion on Drug Delivery, v. 14, n. 5, p. 673-684, MAY 2017. Web of Science Citations: 13. (12/06974-4, 14/14457-5)
PRADO, ANDRESSA R.; YOKAICHIYA, FABIANO; KOBAYASHI DIAS FRANCO, MARGARETH KAZUYO; GONCALVES DA SILVA, CAMILA MORAIS; OLIVEIRA-NASCIMENTO, LAURA; FRANZ-MONTAN, MICHELLE; VOLPATO, MARIA C.; CABECA, LUIS F.; DE PAULA, ENEIDA. Complexation of oxethazaine with 2-hydroxypropyl--cyclodextrin: increased drug solubility, decreased cytotoxicity and analgesia at inflamed tissues. Journal of Pharmacy and Pharmacology, v. 69, n. 6, p. 652-662, JUN 2017. Web of Science Citations: 5. (14/14457-5)
GONCALVES DA SILVA, CAMILA MORAIS; FRACETO, LEONARDO FERNANDES; FRANZ-MONTAN, MICHELLE; COUTO, VERONICA MUNIZ; CASADEI, BRUNA RENATA; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA. Development of egg PC/cholesterol/alpha-tocopherol liposomes with ionic gradients to deliver ropivacaine. Journal of Liposome Research, v. 26, n. 1, p. 1-10, JAN 2 2016. Web of Science Citations: 10. (11/21735-3)
BRAGA, M. A.; MARTINI, M. F.; PICKHOLZ, M.; YOKAICHIYA, F.; FRANCO, M. K. D.; CABECA, L. F.; GUILHERME, V. A.; SILVA, C. M. G.; LIMIA, C. E. G.; DE PAULA, E.. Clonidine complexation with hydroxypropyl-beta-cyclodextrin: From physico-chemical characterization to in vivo adjuvant effect in local anesthesia. Journal of Pharmaceutical and Biomedical Analysis, v. 119, p. 27-36, FEB 5 2016. Web of Science Citations: 7. (06/00121-9)
RODRIGUES DA SILVA, GUSTAVO HENRIQUE; DE MORAIS RIBEIRO, LIGIA NUNES; GUILHERME, VIVIANE APARECIDA; DE CASTRO, SIMONE RAMOS; BREITKREITZ, MARCIA CRISTINA; DE PAULA, ENEIDA. Bupivacaine (S75:R25) Loaded in Nanostructured Lipid Carriers: Factorial Design, HPLC Quantification Method and Physicochemical Stability Study. CURRENT DRUG DELIVERY, v. 15, n. 3, p. 388-396, 2018. Web of Science Citations: 0. (14/14457-5)
SAIA CEREDA, CINTIA MARIA; MECATTI, DANIEL SEBBE; BOAVA PAPINI, JULIANA ZAMPOLI; BUENO, DIEGO VALERIO; FRANZ-MONTAN, MICHELLE; ROCHA, THALITA; PEDRAZZOLI JUNIOR, JOSE; DE PAULA, ENEIDA; DE ARAUJO, DANIELE RIBEIRO; GRILLO, RENATO; et al. Bupivacaine in alginate and chitosan nanoparticles: an in vivo evaluation of efficacy, pharmacokinetics, and local toxicity. JOURNAL OF PAIN RESEARCH, v. 11, p. 683-691, 2018. Web of Science Citations: 2. (14/14457-5)
RODRIGUES DA SILVA, GUSTAVO H.; RIBEIRO, LIGIA N. M.; MITSUTAKE, HERY; GUILHERME, VIVIANE A.; CASTRO, SIMONE R.; POPPI, RONEI J.; BREITKREITZ, MARCIA C.; DE PAULA, ENEIDA. Optimised NLC: a nanotechnological approach to improve the anaesthetic effect of bupivacaine. International Journal of Pharmaceutics, v. 529, n. 1-2, p. 253-263, AUG 30 2017. Web of Science Citations: 11. (14/14457-5)
BARBOSA, RAQUEL DE M.; RIBEIRO, LIGIA N. M.; CASADEI, BRUNA R.; DA SILVA, CAMILA M. G.; QUEIROZ, VIVIANE A.; DURAN, NELSON; DE ARAUJO, DANIELE R.; SEVERINO, PATRICIA; DE PAULA, ENEIDA. Solid Lipid Nanoparticles for Dibucaine Sustained Release. PHARMACEUTICS, v. 10, n. 4, DEC 2018. Web of Science Citations: 4. (14/14457-5)
NASCIMENTO VIEIRA, ANA LAIS; FRANZ-MONTAN, MICHELLE; CABECA, LUIS FERNANDO; DE PAULA, ENEIDA. Anaesthetic benefits of a ternary drug delivery system (Ropivacaine-in-Cyclodextrin-in-Liposomes): in-vitro and in-vivo evaluation. Journal of Pharmacy and Pharmacology, DEC 2019. Web of Science Citations: 0. (14/14457-5)
MUNIZ, BRUNO VILELA; BARATELLI, DIEGO; DI CARLA, STEPHANY; SERPE, LUCIANO; DA SILVA, CAMILA BATISTA; GUILHERME, VIVIANE APARECIDA; DE MORAIS RIBEIRO, LIGIA NUNES; SAIA CEREDA, CINTIA MARIA; DE PAULA, ENEIDA; VOLPATO, MARIA CRISTINA; et al. Hybrid Hydrogel Composed of Polymeric Nanocapsules Co-Loading Lidocaine and Prilocaine for Topical Intraoral Anesthesia. SCIENTIFIC REPORTS, v. 8, DEC 19 2018. Web of Science Citations: 2. (13/22326-5, 12/06974-4, 14/14457-5)
VIGATO, ARYANE ALVES; QUEROBINO, SAMYR MACHADO; DE FARIA, NAIALLY CARDOSO; PINHEIRO DE FREITAS, ANDREA CAROLINA; LEONARDI, GISLAINE RICCI; DE PAULA, ENEIDA; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; DE ARAUJO, DANIELE RIBEIRO. Synthesis and characterization of nanostructured lipid-poloxamer organogels for enhanced skin local anesthesia. European Journal of Pharmaceutical Sciences, v. 128, p. 270-278, FEB 1 2019. Web of Science Citations: 4. (14/14457-5, 18/02482-6, 18/04036-3)
SAIA CEREDA, CINTIA MARIA; GUILHERME, VIVIANE APARECIDA; ALKSCHBIRS, MELISSA INGER; DE BRITO JUNIOR, RUI BARBOSA; TOFOLI, GIOVANA RADOMILLE; FRANZ-MONTAN, MICHELLE; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. Journal of Liposome Research, v. 27, n. 1, p. 74-82, MAR 2017. Web of Science Citations: 1. (06/00121-9)
ORTEGA, VANESSA; GIORGIO, SELMA; DE PAULA, ENEIDA. Liposomal formulations in the pharmacological treatment of leishmaniasis: a review. Journal of Liposome Research, v. 27, n. 3, p. 234-248, 2017. Web of Science Citations: 2. (13/01536-1, 14/12443-7)
GUILHERME, VIVIANE A.; RIBEIRO, LIGIA N. M.; TOFOLI, GIOVANA RADOMILLE; FRANZ-MONTAN, MICHELLE; DE PAULA, ENEIDA; DE JESUS, MARCELO BISPO. Current Challenges and Future of Lipid Nanoparticles Formulations for Topical Drug Application to Oral Mucosa, Skin, and Eye. CURRENT PHARMACEUTICAL DESIGN, v. 23, n. 43, p. 6659-6675, 2017. Web of Science Citations: 5. (14/03002-7, 14/14457-5)
RIBEIRO, LIGIA N. M.; BREITKREITZ, MARCIA C.; GUILHERME, VIVIANE A.; DA SILVA, GUSTAVO H. R.; COUTO, VERONICA M.; CASTRO, SIMONE R.; DE PAULA, BARBARA O.; MACHADO, DAISY; DE PAULA, ENEIDA. Natural lipids-based NLC containing lidocaine: from pre-formulation to in vivo studies. European Journal of Pharmaceutical Sciences, v. 106, p. 102-112, AUG 30 2017. Web of Science Citations: 18. (14/25372-0, 14/14457-5)
RIBEIRO COSTA, JULIANA SOUZA; CRUVINEL, KAREN DE OLIVEIRA; OLIVEIRA-NASCIMENTO, LAURA. A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates. JOURNAL OF ADVANCED RESEARCH, v. 20, p. 33-41, NOV 2019. Web of Science Citations: 1. (17/06613-5, 14/14457-5)
CASADEI, BRUNA RENATA; CARVALHO, PATRICIA DE OLIVEIRA; RISKE, KARIN A.; BARBOSA, RAQUEL DE MELO; DE PAULA, ENEIDA; DOMINGUES, CLEYTON CREPALDI. Brij detergents reveal new aspects of membrane microdomain in erythrocytes. MOLECULAR MEMBRANE BIOLOGY, v. 31, n. 6, p. 195-205, SEP 2014. Web of Science Citations: 7. (09/00904-1, 10/18516-5)
DE JESUS, MARCELO BISPO; RADAIC, ALLAN; ZUHORN, INGE S.; DE PAULA, ENEIDA. Microemulsion extrusion technique: a new method to produce lipid nanoparticles. JOURNAL OF NANOPARTICLE RESEARCH, v. 15, n. 10, SEP 3 2013. Web of Science Citations: 7. (09/13110-3, 12/01038-9)
DE ARAUJO, DANIELE R.; DA SILVA, DEYSE C.; BARBOSA, RAQUEL M.; FRANZ-MONTAN, MICHELLE; CEREDA, CINTIA M. S.; PADULA, CRISTINA; SANTI, PATRIZIA; DE PAULA, ENEIDA. Strategies for delivering local anesthetics to the skin: focus on liposomes, solid lipid nanoparticles, hydrogels and patches. Expert Opinion on Drug Delivery, v. 10, n. 11, p. 1551-1563, NOV 2013. Web of Science Citations: 31. (10/11475-1, 06/00121-9, 11/05581-6)
SANTOS AKKARI, ALESSANDRA CRISTINA; RAMOS CAMPOS, ESTEFANIA VANGELIE; KEPPLER, ARTUR FRANZ; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA; TOFOLI, GIOVANA RADOMILLE; DE ARAUJO, DANIELE RIBEIRO. Budesonide-hydroxypropyl-beta-cyclodextrin inclusion complex in binary poloxamer 407/403 system for ulcerative colitis treatment: A physico-chemical study from micelles to hydrogels. COLLOIDS AND SURFACES B-BIOINTERFACES, v. 138, p. 138-147, FEB 1 2016. Web of Science Citations: 12. (14/26200-9, 14/14457-5)
FRANZ-MONTAN, MICHELLE; BARONI, DANIELA; BRUNETTO, GIOVANA; VIEIRA SOBRAL, VIVIANE ROBERTA; GONCALVES DA SILVA, CAMILA MORAIS; VENANCIO, PAULO; ZAGO, PATRICIA WIZIACK; SAIA CEREDA, CINTIA MARIA; VOLPATO, MARIA CRISTINA; DE ARAUJO, DANIELE RIBEIRO; et al. Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans. Journal of Liposome Research, v. 25, n. 1, p. 11-19, MAR 2015. Web of Science Citations: 21. (06/00121-9, 09/08860-3, 07/05734-1)
DE ARAUJO, DANIELE RIBEIRO; PADULA, CRISTINA; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; BRITO, JR., RUI BARBOSA; DE PAULA, ENEIDA; NICOLI, SARA; SANTI, PATRIZIA. Bioadhesive Films Containing Benzocaine: Correlation Between In Vitro Permeation and In Vivo Local Anesthetic Effect. PHARMACEUTICAL RESEARCH, v. 27, n. 8, p. 1677-1686, AUG 2010. Web of Science Citations: 22. (06/00121-9)
GRILLO, RENATO; DE MELO, NATHALIE F. S.; DE ARAUJO, DANIELE R.; DE PAULA, ENEIDA; DIAS FILHO, NEWTON L.; ROSA, ANDRE H.; FRACETO, LEONARDO F.. Validation of an HPLC Method for quantitative Determination of Benzocaine in PHBV-Microparticles and PLA-Nanoparticles. Latin American Journal of Pharmacy, v. 28, n. 3, p. 393-399, MAY-JUN 2009. Web of Science Citations: 16. (08/01222-9, 06/00121-9)
GRILLO, RENATO; DE MELO, NATHALIE F. S.; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA; ROSA, ANDRE HENRIQUE; FRACETO, LEONARDO FERNANDES. Polymeric alginate nanoparticles containing the local anesthetic bupivacaine. Journal of Drug Targeting, v. 18, n. 9, p. 688-699, NOV 2010. Web of Science Citations: 44. (08/01222-9, 06/00121-9)
PRETÉ‚ PSC; MALHEIROS‚ SVP; MEIRELLES‚ NC; DE PAULA‚ E.. Quantitative assessment of human erythrocyte membrane solubilization by Triton X-100. Biophysical Chemistry, v. 97, n. 1, p. 1-5, 2002.
PRETÉ‚ PSC; GOMES‚ K.; MALHEIROS‚ SVP; MEIRELLES‚ NC; DE PAULA‚ E.. Solubilization of human erythrocyte membranes by non-ionic surfactants of the polyoxyethylene alkyl ethers series. Biophysical Chemistry, v. 97, n. 1, p. 45-54, 2002.
DE PAULA, ENEIDA; CEREDA, CINTIA M. S.; FRACETO, LEONARDO F.; DE ARAUJO, DANIELE R.; FRANZ-MONTAN, MICHELLE; TOFOLI, GIOVANA R.; RANALI, JOSE; VOLPATO, MARIA C.; GROPPO, FRANCISCO C.. Micro and nanosystems for delivering local anesthetics. Expert Opinion on Drug Delivery, v. 9, n. 12, p. 1505-1524, DEC 2012. Web of Science Citations: 48. (06/00121-9)
VOLOBUEF, CRISTIANE; MORAES, CAROLINA M.; NUNES, LAZARO A. S.; CEREDA, CINTIA M. S.; YOKAICHIYA, FABIANO; FRANCO, MARGARETH K. K. D.; BRAGA, ANGELICA F. A.; DE PAULA, ENEIDA; TOFOLI, GIOVANA RADOMILLE; FRACETO, LEONARDO F.; et al. Sufentanil-2-hydroxypropyl-beta-cyclodextrin inclusion complex for pain treatment: Physicochemical, cytotoxicity, and pharmacological evaluation. Journal of Pharmaceutical Sciences, v. 101, n. 10, p. 3698-3707, OCT 2012. Web of Science Citations: 6. (10/11475-1, 06/00121-9)
FRANCO DE LIMA, ROBERTA ALINE; DE JESUS, MARCELO BISPO; SAIA CEREDA, CINTIA MARIA; TOFOLI, GIOVANA RADOMILLE; CABECA, LUIS FERNANDO; MAZZARO, IRINEU; FRACETO, LEONARDO FERNANDES; DE PAULA, ENEIDA. Improvement of tetracaine antinociceptive effect by inclusion in cyclodextrins. Journal of Drug Targeting, v. 20, n. 1, p. 85-96, JAN 2012. Web of Science Citations: 23. (06/03838-1)
TOFOLI, GIOVANA RADOMILLE; CEREDA, CINTIA M. S.; ARAUJO, DANIELE RIBEIRO; FRANZ-MONTAN, MICHELLE; GROPPO, FRANCISCO CARLOS; QUAGLIO, DAIANE; PEDRAZZOLI JUNIOR, JOSE; CALAFATTI, SILVANA APARECIDA; PROENCA BARROS, FABIO ALESSANDRO; DE PAULA, ENEIDA. Pharmacokinetic study of liposome-encapsulated and plain mepivacaine formulations injected intra-orally in volunteers. Journal of Pharmacy and Pharmacology, v. 64, n. 3, p. 397-403, MAR 2012. Web of Science Citations: 7. (06/00121-9)
FRANZ-MONTAN, M.; DE PAULA, E.; GROPPO, F. C.; SILVA, A. L. R.; RANALI, J.; VOLPATO, M. C.. Liposomal delivery system for topical anaesthesia of the palatal mucosa. BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, v. 50, n. 1, p. 60-64, JAN 2012. Web of Science Citations: 19. (06/00121-9)
SILVA DE MELO, NATHALIE FERREIRA; GRILLO, RENATO; GUILHERME, VIVIANE APARECIDA; DE ARAUJO, DANIELE RIBEIRO; DE PAULA, ENEIDA; ROSA, ANDRE HENRIQUE; FRACETO, LEONARDO FERNANDES. Poly(Lactide-co-Glycolide) Nanocapsules Containing Benzocaine: Influence of the Composition of the Oily Nucleus on Physico-Chemical Properties and Anesthetic Activity. PHARMACEUTICAL RESEARCH, v. 28, n. 8, p. 1984-1994, AUG 2011. Web of Science Citations: 29. (06/00121-9)
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