CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Hospital da Mulher Professor Doutor José Aristodemo Pinotti. Centro de Atenção Integral à Saúde da Mulher (CAISM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Pontifícia Universidade Católica de Campinas (1986), master's at Ciências Biológicas na Área de Biologia Celular from Universidade Estadual de Campinas (1990) and doctorate at Biochemistry from Universidade Estadual de Campinas (2000). He is currently responsável pelo biobanco caism at Universidade Estadual de Campinas. , acting on the following subjects: imunidade inata, células nk, imunoterapia, leucemia and imunoseleção de células tumorais. (Source: Lattes Curriculum)
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Natural killer lymphocytes (NK) are known for the ability to kill neoplastic cells and fight the metastatic spread of cancer. Metastatic dissemination is the main cause of death associated with cancer, especially in advanced epithelial ovarian cancer (EOC). We have recently shown that functional performance of NK cells is significantly higher in EOC associated-ascites without malignant ce…
The natural killer (NK) cells are cytotoxic lymphocytes that act innately in defending the body against viral infections and neoplasms. Recently, we have demonstrated that it is possible to obtain enriched NK cell preparations from patients with ovarian cancer by long-term in vitro culture of peripheral blood mononuclear cells (PBMC). The effector cells thus obtained possess significantly…
We have shown recently the possibility of generating effector cell preparations enriched with CD56+ lymphocytes, NK and NKT-like, by ex vivo expansion of peripheral blood mononuclear cells (PBMC) from patients with ovarian cancer (FAPESP 2006/04900-2). The current project proposes to evaluate the receptor repertoire (inhibitory receptors: KIR2DL1, KIR2DL2/3 and KIR3DL1 and activating rece…
(Only some records are available in English at this moment)
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