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Edecio Cunha Neto

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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Associate Professor and head of the Laboratory of Clinical immunology and Allergy (LIM-60), Division of Clinical Immunology and Allergy, Department of Medicine, and Investigator of the Heart Institute/Fundação Zerbini, University of São Paulo School of Medicine. Investigator class 1A, CNPq (Brazilian National Research Council). Investigator of the INCT for Investigation in Immunology.MD degree, University of Brasília (1988) and PhD on Immunology, University of São Paulo (1994). Post-doctoral/visiting researcher stays in Stanford University (1991), Harvard University (2002) and Istituto Roche Milano Ricerche, Italy (1996). He has experience in translational research on cellular and molecular immunology and immunopathology of human disease, focussing on the following subjects:Chagas disease, chronic Chagas disease cardiomyopathy, autoimmunity, vaccine discovery and development, mechanisms in allergy. Recent emphasis has been on the role of mitochondrial damage, inflammation and genetics, as well as novel treatments for Chagas disease. identification of key energy metabolism changes in Chagas' cardiomyopathy and on development of a COVID-19 vaccine and identification of COVID-19 biomarkers. In June 2020 he had 140 publications in peer-reviewed, indexed journals. The publications had been cited 4150 times, with an h index of 36 (ISI/WoS). One patent on an HIV vaccine was granted by USPTO and EPO (US and European Community) and pending in INPI (Brazil). Awarded with the Roche (1994), Santista-Juventude (1998) e Jairo Ramos (2002) nationwide scientific awards. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
FAPESP support in numbers * Updated July 04, 2020
Total / Available in English
1 / 1 Ongoing research grants
21 / 14 Completed research grants
32 / 14 Completed scholarships in Brazil
1 / 0 Completed scholarships abroad
55 / 29 All research grants and scholarships

Associated processes
Most frequent collaborators in research granted by FAPESP
Contact researcher

Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.


 

 

 

 

Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (13)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications9
Citations120
Cit./Article13.3
Data from Web of Science

LAUGIER, LAURIE; FRADE, AMANDA FARAGE; FERREIRA, FREDERICO MORAES; BARON, MONIQUE ANDRADE; TEIXEIRA, PRISCILA CAMILLO; CABANTOUS, SANDRINE; PINTO FERREIRA, LUDMILA RODRIGUES; LOUIS, LAURENCE; CARVALHO RIGAUD, VAGNER OLIVEIRA; GAIOTTO, FABIO ANTONIO; et al. Whole-Genome Cardiac DNA Methylation Fingerprint and Gene Expression Analysis Provide New Insights in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy. Clinical Infectious Diseases, v. 65, n. 7, p. 1103-1111, . Web of Science Citations: 4. (13/50302-3)

PINTO FERREIRA, LUDMILA RODRIGUES; FRADE, AMANDA FARAGE; BARROS SANTOS, RONALDO HONORATO; TEIXEIRA, PRISCILA CAMILLO; BARON, MONIQUE ANDRADE; NAVARRO, ISABELA CUNHA; BENVENUTI, LUIZ ALBERTO; FIORELLI, ALFREDO INACIO; BOCCHI, EDIMAR ALCIDES; STOLF, NOEDIR ANTONIO; et al. MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 175, n. 3, p. 409-417, . Web of Science Citations: 33. (08/57881-0, 13/50302-3, 12/08107-6)

PINTO FERREIRA, LUDMILA RODRIGUES; FERREIRA, FREDERICO MORAES; LAUGIER, LAURIE; CABANTOUS, SANDRINE; NAVARRO, ISABELA CUNHA; CANDIDO, DARLAN DA SILVA; RIGAUD, VAGNER CARVALHO; REAL, JULIANA MONTE; PEREIRA, GLAUCIA VILAR; PEREIRA, ISABELA RESENDE; et al. Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection. SCIENTIFIC REPORTS, v. 7, . Web of Science Citations: 4. (13/50302-3)

DE CAMPOS, LUCILA; SANTOS GALVAO, CLOVIS EDUARDO; MAIRENA, ELIANE CONTI; VOEGELS, RICHARD; KALIL, JORGE; CASTRO, FABIO MORATO; CUNHA-NETO, EDECIO. Increased gene expression of inflammatory markers in nasal turbinate of patients with persistent allergic rhinitis and chronic obstruction. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, v. 276, n. 11, p. 3247-3249, . Web of Science Citations: 0.

CHEVILLARD, CHRISTOPHE; NUNES, JOAO PAULO SILVA; FRADE, AMANDA FARAGE; ALMEIDA, RAFAEL RIBEIRO; PANDEY, RAMENDRA PATI; NASCIMENTO, MARILDA SAVOIA; KALIL, JORGE; CUNHA-NETO, EDECIO. Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy. FRONTIERS IN IMMUNOLOGY, v. 9, . Web of Science Citations: 3. (14/50890-5, 16/15209-0, 13/50302-3)

FONSECA‚ S.G.; COUTINHO-SILVA‚ A.; FONSECA‚ L.A.M.; SEGURADO‚ A.C.; MORAES‚ S.L.; RODRIGUES‚ H.; HAMMER‚ J.; KALLÁS‚ E.G.; SIDNEY‚ J.; SETTE‚ A.; et al. Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients. AIDS, v. 20, n. 18, p. 2263-2273, . (01/00729-3)

PINTO FERREIRA, LUDMILA RODRIGUES; FERREIRA, FREDERICO MORAES; NAKAYA, HELDER IMOTO; DENG, XUTAO; CNDIDO, DARLAN DA SILVA; DE OLIVEIRA, LEA CAMPOS; BILLAUD, JEAN-NOEL; LANTERI, MARION C.; RIGAUD, VAGNER OLIVEIRA-CARVALHO; SEIELSTAD, MARK; et al. Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction. Journal of Infectious Diseases, v. 215, n. 3, p. 387-395, . Web of Science Citations: 11. (13/50302-3)

NAVARRO, ISABELA CUNHA; FERREIRA, FREDERICO MORAES; NAKAYA, HELDER I.; BARON, MONIQUE ANDRADE; VILAR-PEREIRA, GLAUCIA; PEREIRA, ISABELA RESENDE; GONCALVES SILVA, ANA MARIA; REAL, JULIANA MONTE; DE BRITO, THALES; CHEVILLARD, CHRISTOPHE; et al. MicroRNA Transcriptome Profiling in Heart of Trypanosoma cruzi-Infected Mice: Parasitological and Cardiological Outcomes. PLoS Neglected Tropical Diseases, v. 9, n. 6, . Web of Science Citations: 11. (13/50302-3, 12/08107-6)

NOGUEIRA, LUCIANA GABRIEL; BARROS SANTOS, RONALDO HONORATO; IANNI, BARBARA MARIA; FIORELLI, ALFREDO INACIO; MAIRENA, ELIANE CONTI; BENVENUTI, LUIZ ALBERTO; FRADE, AMANDA; DONADI, EDUARDO; DIAS, FABRICIO; SABA, BRUNO; et al. Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10. PLoS Neglected Tropical Diseases, v. 6, n. 10, . Web of Science Citations: 49.

CUNHA-NETO, EDECIO; ROSA, DANIELA S.; HARRIS, PAUL E.; OLSON, TIM; MORROW, ALEX; CIOTLOS, SERBAN; HERST, CHARLES V.; RUBSAMEN, REID MARTIN. An Approach for a Synthetic CTL Vaccine Design against Zika Flavivrus Using Class I and Class II Epitopes Identified by Computer Modeling. FRONTIERS IN IMMUNOLOGY, v. 8, . Web of Science Citations: 5. (13/50302-3)

PINTO FERREIRA, LUDMILA RODRIGUES; FERREIRA, FREDERICO MORAES; LAUGIER, LAURIE; CABANTOUS, SANDRINE; NAVARRO, ISABELA CUNHA; CANDIDO, DARLAN DA SILVA; RIGAUD, VAGNER CARVALHO; REAL, JULIANA MONTE; PEREIRA, GLAUCIA VILAR; PEREIRA, ISABELA RESENDE; et al. Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection. SCIENTIFIC REPORTS, v. 7, . Web of Science Citations: 4. (13/50302-3)

PINTO FERREIRA, LUDMILA RODRIGUES; FERREIRA, FREDERICO MORAES; NAKAYA, HELDER IMOTO; DENG, XUTAO; CNDIDO, DARLAN DA SILVA; DE OLIVEIRA, LEA CAMPOS; BILLAUD, JEAN-NOEL; LANTERI, MARION C.; RIGAUD, VAGNER OLIVEIRA-CARVALHO; SEIELSTAD, MARK; et al. Blood Gene Signatures of Chagas Cardiomyopathy With or Without Ventricular Dysfunction. Journal of Infectious Diseases, v. 215, n. 3, p. 387-395, . Web of Science Citations: 11. (13/50302-3)

PINTO FERREIRA, LUDMILA RODRIGUES; FRADE, AMANDA FARAGE; BARROS SANTOS, RONALDO HONORATO; TEIXEIRA, PRISCILA CAMILLO; BARON, MONIQUE ANDRADE; NAVARRO, ISABELA CUNHA; BENVENUTI, LUIZ ALBERTO; FIORELLI, ALFREDO INACIO; BOCCHI, EDIMAR ALCIDES; STOLF, NOEDIR ANTONIO; et al. MicroRNAs miR-1, miR-133a, miR-133b, miR-208a and miR-208b are dysregulated in Chronic Chagas disease Cardiomyopathy. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 175, n. 3, p. 409-417, . Web of Science Citations: 33. (08/57881-0, 13/50302-3, 12/08107-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ALMEIDA, Rafael Ribeiro. Reconhecimento entre clados e efeito supressor induzido por vacinas de DNA codificando peptídeos conservados e promíscuos do grupo M do HIV-1. Tese (Doutorado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (12/03760-3

SANTANA, Vinicius Canato. Desenvolvimento de estratégias para aumento da imunogenicidade da vacina de DNA HIVBr18 baseadas na fusão com a glicoproteína D do herpes vírus humano tipo 1 e na coadministração de citocinas. Tese (Doutorado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (11/02815-6

ALMEIDA, Rafael Ribeiro. Imunogenicidade de vacinas de DNA codificando peptídeos conservados e promíscuos do HIV-1,  em camundongos BALB/c. Dissertação (Mestrado) -  Faculdade de Medicina.  Universidade de São Paulo (USP).  São Paulo.  (09/03141-9

Patent applications

EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION EP20060775031 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto; Jorge Elias Kalil Filho; Simone Gonçalves da Fonseca - April 2006, 09

EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION PCT/BR2006/000175 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto; Jorge Elias Kalil Filho; Simone Gonçalves da Fonseca - April 2006, 09

EPÍTOPOS, COMBINAÇÃO DE EPÍTOPOS, USOS DE EPÍTOPOS OU SUA COMBINAÇÃO, COMPOSIÇÃO, USOS DA COMPOSIÇÃO, VACINAS PROFILÁTICAS ANTI-HIV-1, VACINAS TERAPÊUTICAS, MÉTODO PARA A IDENTIFICAÇÃO DE EPÍTOPOS E MÉTODOS PARA O TRATAMENTO OU PREVENÇÃO PI0504117-1 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto; Jorge Elias Kalil Filho; Simone Gonçalves da Fonseca - September 2005, 05

EPITOPES, COMBINED EPITOPES, USE OF EPITOPES OR THEIR COMBINATION, COMPOSITION, USES OF THE COMPOSITION, ANTI- HIV-I PROPHYLACTIC VACCINES, THERAPEUTIC VACCINES, METHOD FOR THE IDENTIFICATION OF EPITOPES AND METHODS FOR TREATMENT AND PREVENTION US12/073,401 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação Zerbini; Universidade de São Paulo (USP). Edecio Cunha Neto; Jorge Elias Kalil Filho; Simone Gonçalves da Fonseca - March 2008, 05

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