CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor and head of the Laboratory of Clinical immunology and Allergy (LIM-60), Division of Clinical Immunology and Allergy, Department of Medicine, and Investigator of the Heart Institute/Fundação Zerbini, University of São Paulo School of Medicine (FMUSP). Investigator class 1B, CNPq (Brazilian National Research Council). Coordinator of the Graduate Program of Allergy and Immunopathology at FMUSP. Investigator of the INCT for Investigation in Immunology.MD degree, University of Brasília (1988) and PhD on Immunology, University of São Paulo (1994). Visiting researcher in Stanford University (USA, 1991), Harvard University (USA, 2002), Istituto Roche Milano Ricerche, Italy (1996) and Aix-Marseille Université/INSERM, France ( 2012, 2017). He has experience in translational research on cellular and molecular immunology and immunopathology of human disease, focussing on the following subjects:Chagas disease, chronic Chagas disease cardiomyopathy, vaccine discovery, HIV, COVID-19. Recent emphasis has been on the role of mitochondrial damage, inflammation and genetics, as well as novel treatments for Chagas disease, and identification of biomarkers and vaccine development for COVID-19. In March 2025 I had 201 publications in peer-reviewed, indexed journals. The publications had been cited 7255 times, with an h index of 48 (Scopus). According th the Research.com ranking site, Edecio is among the 20 most prolific immunologists in Brazil. He has mentored 17 post-doctoral fellows, 16 PhD students, 15 M.Sci. students, and 30 undergraduate students. One patent on an HIV vaccine was granted by USPTO and EPO (US and European Community) and pending in INPI (Brazil). Awarded with the Roche (1994), Santista-Juventude (1998) e Jairo Ramos (2002) nationwide scientific awards. (Source: Lattes Curriculum)
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In the last decade, advances in the area of automated microscopy have revealed new possibilities for functional assays, allowing the analysis of a broad spectrum of phenotypic changes at the cellular level. High Content Screening (HCS) is an approach to cell biology that combines automated multicolor fluorescence imaging and quantitative data analysis in a high-throughput format suitable …
Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, is a neglected disease affecting around 6 million people, with no effective antiparasitic drugs or vaccines. About 30% of CD patients develop chronic Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy that occurs decades after the initial infection, while most infected patients (60%) remain asymptoma…
Chagas Disease, caused by the protozoan parasite Trypanosoma cruzi, affects 5-8 million people worldwide. Only a fraction of infected patients develop chronic cardiac or digestive disease. The factors underlying the differential susceptibility to developing either of the symptomatic forms of chronic Chagas Disease are incompletely understood. During the chronic phase of infection, 30% of …
Dr Christophe Chevillard's scientific visit is crucial for the collaborative scientific program, which so far has shown to be very productive. It allowed publication of 14 scientific papers, 5 in various steps of writing; 7 supported grant proposals (two currently submitted and awaiting review). We will perform additional analysis and processing of data obtained in FAPESP/ANR collaborat…
Chagas disease, caused by the protozoan Trypanosoma cruzi, affects 15 million people. About 30% of Chagas disease patients develop Chronic Chagas disease cardiomyopathy (CCC), an particularly lethal inflammatory cardiomyopathy that occurs decades after the initial infection, while most patients remain asymptomatic (ASY;60%). Clinical severity in Chagas disease is correlated with the occur…
(Only some records are available in English at this moment)
It is estimated that 6 to 7 million people are infected with Trypanosoma cruzi worldwide. Chagas disease, caused by this parasite, is endemic in Latin America, where it is a major cause of hospitalization for heart failure. About 30% of those infected progress in the chronic phase of the infection to chronic Chagas' heart disease (CCC), characterized by persistent destructive myocarditis,…
About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy that occurs decades after the initial infection, while most infected patients (60%) remain asymptomatic in the so-called indeterminate form (IF). Myocardial fibrosis, inflammation and mitochondrial dysfunction are involved in the arrhythmia substrate and triggering even…
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, affects around 6 million people, with no effective antiparasitic medications or vaccines. About 30% of CD patients develop chronic Chagasic cardiomyopathy (CCC), an inflammatory myocardial disease that occurs decades after infection. Death results from heart failure or arrhythmia in a subset of CCC patients. Myocardial fibros…
About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy that occurs decades after the initial infection, while most infected patients (60%) remain asymptomatic in the so-called indeterminate form (IF). Myocardial fibrosis, inflammation and mitochondrial dysfunction are involved in the arrhythmia substrate and triggering even…
About 30% of Chagas disease patients develop chronic Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy that occurs decades after the initial infection, while most infected patients (60%) remain asymptomatic in the so-called indeterminate form (IF). Myocardial fibrosis, inflammation and mitochondrial dysfunction are involved in the arrhythmia substrate and triggering even…
(Only some records are available in English at this moment)
The pandemic of coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, has affected millions of people worldwide since its beginning in 2019. Even with the current availability of different vaccines and new antivirals and immunomodulatory interventions, thousands of infection cases and deaths are still registered daily. Although most infected individuals present mild to moderate …
| 2 / 2 | Ongoing grants |
| 23 / 16 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 37 / 19 | Completed scholarships in Brazil |
| 2 / 1 | Completed scholarships abroad |
| 67 / 41 | All research grants and scholarships |
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